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- W2026366922 endingPage "669" @default.
- W2026366922 startingPage "660" @default.
- W2026366922 abstract "To develop a rational approach to outpatient management, we review the pharmacologic properties of low-molecular-weight heparins and their efficacy in clinical trials of deep vein thrombosis treatment. Low-molecular-weight heparins have better bioavailability and more predictable anticoagulant activity than standard heparin and thus can be administered without routine laboratory monitoring. Randomized trials comparing subcutaneous low-molecular-weight heparin administered primarily at home with inpatient intravenous standard heparin have established the safety and efficacy of outpatient treatment of selected patients. However, many patients were excluded from these studies. The benefits demonstrated in carefully controlled clinical trials of outpatient treatment of deep vein thrombosis required a complex multidisciplinary organization of medical care that is not readily achievable in routine practice. A structured protocol is necessary to ensure that patient care is optimal. The essential components of an outpatient program include appropriate patient selection, adequate patient education, daily follow-up during therapy with low-molecular-weight heparin, and easy access to health-care professionals." @default.
- W2026366922 created "2016-06-24" @default.
- W2026366922 creator A5032830120 @default.
- W2026366922 creator A5039564788 @default.
- W2026366922 date "1999-06-01" @default.
- W2026366922 modified "2023-09-27" @default.
- W2026366922 title "Outpatient treatment of deep vein thrombosis: translating clinical trials into practice" @default.
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- W2026366922 doi "https://doi.org/10.1016/s0002-9343(99)00129-1" @default.
- W2026366922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10378625" @default.
- W2026366922 hasPublicationYear "1999" @default.