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- W2026387680 abstract "The single-strand-RNA binding protein KSRP is able to negatively regulate gene expression operating with at least two distinct and integrated postranscriptional mechanisms: (i) by promoting decay of unstable mRNAs and (ii) by favoring maturation from precursors of select microRNAs (miRNAs) including the prototypical tumor suppressor let-7. Studies performed in primary and cultured cells as well as in mice proved that the ability of KSRP to integrate different levels of gene expression is required for proper immune response, lipid metabolism, cell-fate decisions, tissue regeneration, and DNA damage response." @default.
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- W2026387680 date "2014-10-01" @default.
- W2026387680 modified "2023-10-16" @default.
- W2026387680 title "KSRP Controls Pleiotropic Cellular Functions" @default.
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- W2026387680 doi "https://doi.org/10.1016/j.semcdb.2014.05.004" @default.
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