FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026410273> ?p ?o ?g. }

• W2026410273 endingPage "923" @default.
• W2026410273 startingPage "919" @default.
• W2026410273 abstract "Chronic kidney disease is associated with an increased risk of ischemic and bleeding events after percutaneous coronary intervention (PCI). The direct thrombin inhibitor bivalirudin reduces these combined events. We sought to assess whether this benefit was influenced by renal function. A meta-analysis of 3 randomized trials (n = 5,035) comparing bivalirudin with heparin during PCI, stratified by estimated creatinine clearance using the Cockcroft-Gault equation (>90 [n = 1,578], 90 to 60 [n = 2,163], 59 to 30 [n = 1,255], and <30 ml/min [n = 39]), was conducted. The composite end points of death, myocardial infarction or revascularization, hemorrhage, and combined ischemic or bleeding events were assessed. A common odds ratio for each creatinine clearance strata was estimated with a random-effects model. The interaction between renal impairment and benefit from bivalirudin was assessed. Adverse ischemic and bleeding events increased with decreasing renal function. The relative benefit of bivalirudin with respect to ischemic and bleeding events was maintained within each stratum. The absolute benefit in terms of ischemic and bleeding complications increased with decreasing creatinine clearance (normal 2.2%, mild 5.8%, moderate 7.7%, severe 14.4%; p trend <0.001, interaction p = 0.044). Renal dysfunction remains a prevalent risk factor for ischemic and bleeding events in patients who undergo PCI. Bivalirudin provides greater absolute benefit in patients with impaired renal function." @default.
• W2026410273 created "2016-06-24" @default.
• W2026410273 creator A5001994412 @default.
• W2026410273 creator A5008382551 @default.
• W2026410273 creator A5010240121 @default.
• W2026410273 creator A5010571732 @default.
• W2026410273 creator A5050863307 @default.
• W2026410273 creator A5078207171 @default.
• W2026410273 creator A5080398948 @default.
• W2026410273 creator A5086611754 @default.
• W2026410273 creator A5087016151 @default.
• W2026410273 date "2003-10-01" @default.
• W2026410273 modified "2023-09-26" @default.
• W2026410273 title "Bivalirudin provides increasing benefit with decreasing renal function: a meta-analysis of randomized trials" @default.
• W2026410273 cites W1550111394 @default.
• W2026410273 cites W1894514973 @default.
• W2026410273 cites W1971372861 @default.
• W2026410273 cites W1985992748 @default.
• W2026410273 cites W1990705137 @default.
• W2026410273 cites W2017509342 @default.
• W2026410273 cites W2025954547 @default.
• W2026410273 cites W2030371097 @default.
• W2026410273 cites W2036669264 @default.
• W2026410273 cites W2055875089 @default.
• W2026410273 cites W2058740428 @default.
• W2026410273 cites W2076917048 @default.
• W2026410273 cites W2077813066 @default.
• W2026410273 cites W2082333685 @default.
• W2026410273 cites W2087250914 @default.
• W2026410273 cites W2099882339 @default.
• W2026410273 cites W2107328434 @default.
• W2026410273 cites W2113456576 @default.
• W2026410273 cites W2119696625 @default.
• W2026410273 cites W2128661749 @default.
• W2026410273 cites W2130652855 @default.
• W2026410273 cites W2143147344 @default.
• W2026410273 cites W2145725837 @default.
• W2026410273 cites W2335915210 @default.
• W2026410273 doi "https://doi.org/10.1016/s0002-9149(03)00970-6" @default.
• W2026410273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14556866" @default.
• W2026410273 hasPublicationYear "2003" @default.
• W2026410273 type Work @default.
• W2026410273 sameAs 2026410273 @default.
• W2026410273 citedByCount "91" @default.
• W2026410273 countsByYear W20264102732012 @default.
• W2026410273 countsByYear W20264102732013 @default.
• W2026410273 countsByYear W20264102732014 @default.
• W2026410273 countsByYear W20264102732015 @default.
• W2026410273 countsByYear W20264102732016 @default.
• W2026410273 countsByYear W20264102732017 @default.
• W2026410273 countsByYear W20264102732019 @default.
• W2026410273 countsByYear W20264102732020 @default.
• W2026410273 countsByYear W20264102732021 @default.
• W2026410273 crossrefType "journal-article" @default.
• W2026410273 hasAuthorship W2026410273A5001994412 @default.
• W2026410273 hasAuthorship W2026410273A5008382551 @default.
• W2026410273 hasAuthorship W2026410273A5010240121 @default.
• W2026410273 hasAuthorship W2026410273A5010571732 @default.
• W2026410273 hasAuthorship W2026410273A5050863307 @default.
• W2026410273 hasAuthorship W2026410273A5078207171 @default.
• W2026410273 hasAuthorship W2026410273A5080398948 @default.
• W2026410273 hasAuthorship W2026410273A5086611754 @default.
• W2026410273 hasAuthorship W2026410273A5087016151 @default.
• W2026410273 hasConcept C126322002 @default.
• W2026410273 hasConcept C156957248 @default.
• W2026410273 hasConcept C159641895 @default.
• W2026410273 hasConcept C164705383 @default.
• W2026410273 hasConcept C168563851 @default.
• W2026410273 hasConcept C2776301958 @default.
• W2026410273 hasConcept C2776710957 @default.
• W2026410273 hasConcept C2777565915 @default.
• W2026410273 hasConcept C2778653478 @default.
• W2026410273 hasConcept C2778810321 @default.
• W2026410273 hasConcept C2779161974 @default.
• W2026410273 hasConcept C2780306776 @default.
• W2026410273 hasConcept C2780400711 @default.
• W2026410273 hasConcept C45393284 @default.
• W2026410273 hasConcept C500558357 @default.
• W2026410273 hasConcept C71924100 @default.
• W2026410273 hasConceptScore W2026410273C126322002 @default.
• W2026410273 hasConceptScore W2026410273C156957248 @default.
• W2026410273 hasConceptScore W2026410273C159641895 @default.
• W2026410273 hasConceptScore W2026410273C164705383 @default.
• W2026410273 hasConceptScore W2026410273C168563851 @default.
• W2026410273 hasConceptScore W2026410273C2776301958 @default.
• W2026410273 hasConceptScore W2026410273C2776710957 @default.
• W2026410273 hasConceptScore W2026410273C2777565915 @default.
• W2026410273 hasConceptScore W2026410273C2778653478 @default.
• W2026410273 hasConceptScore W2026410273C2778810321 @default.
• W2026410273 hasConceptScore W2026410273C2779161974 @default.
• W2026410273 hasConceptScore W2026410273C2780306776 @default.
• W2026410273 hasConceptScore W2026410273C2780400711 @default.
• W2026410273 hasConceptScore W2026410273C45393284 @default.
• W2026410273 hasConceptScore W2026410273C500558357 @default.
• W2026410273 hasConceptScore W2026410273C71924100 @default.
• W2026410273 hasIssue "8" @default.
• W2026410273 hasLocation W20264102731 @default.
• W2026410273 hasLocation W20264102732 @default.

• next