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- W2026422068 abstract "Contents We investigated the use of a commercial gonadotropin‐releasing hormone ( G n RH ) vaccine as a method of temporary and reversible immunocastration in intact male dogs. Four privately owned dogs were vaccinated twice at 4‐week intervals. Blood samples were collected at 0, 4, 12 and 20 weeks following the initial vaccination. These samples were analysed for G n RH antibody titres, luteinizing hormone ( LH ) and testosterone concentrations. Scrotal measurements were made at the time of sample collection, and testicular volume was calculated using the formula of an ellipsoid. As a result of vaccination, dogs displayed an elevated G n RH antibody titre, decreased LH and testosterone concentrations and decreased testicular volume, which reversed by the end of the study period. Therefore, these results suggest that immunizing against G n RH may be a possible choice for temporary and reversible immunocastration." @default.
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- W2026422068 date "2012-12-01" @default.
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- W2026422068 title "Physiologic Responses Following Gonadotropin-Releasing Hormone Immunization in Intact Male Dogs" @default.
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- W2026422068 doi "https://doi.org/10.1111/rda.12017" @default.
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