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• W2026464868 abstract "Despite the availability of efficacious treatments for bipolar disorder, their effectiveness in general clinical practice is greatly attenuated, resulting in what has been called an 'efficacy-effectiveness gap'. In designing VA Cooperative Studies Program (CSP) Study #430 to address this gap, nine principles for conducting an effectiveness (in contrast to an efficacy) study were identified. These principles are presented and discussed, with specific aspects of CSP #430 serving as illustrations of how they can be implemented in an actual study. CSP #430 hypothesizes that an integrated, clinic-based treatment delivery system that emphasizes (1) algorithm-driven somatotherapy, (2) standardized patient education, and (3) easy access to a single primary mental health care provider to maximize continuity-of-care, will address the efficacy-effectiveness gap and improve disease, functional, and economic outcome. It is an 11-site, randomized controlled clinical trial of this multi-modal, clinic-based intervention versus usual VA care running from 1997 to 2003. The trial has enrolled 191 subjects in each arm, using minimal exclusion criteria to maximize the external validity of the study. Subjects are followed for 3 years. The intervention is highly specified in a series of operations manuals for each of the three components. Several continuous quality improvement (CQI) interventions, process measures, and statistical techniques deal with drift of care in both the intervention and usual care arms to ensure the internal validity of the study. CSP #430 is designed to have impact well beyond the VA, since it evaluates a basic health care operational principle: that augmenting ambulatory access for major mental illness will improve outcome and reduce overall treatment costs. If results are positive, this study will provide a reason to reconsider the prevailing trend toward limitation of ambulatory services that is characteristic of many managed care systems today." @default.
• W2026464868 created "2016-06-24" @default.
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• W2026464868 date "2001-12-01" @default.
• W2026464868 modified "2023-09-24" @default.
• W2026464868 title "Principles of effectiveness trials and their implementation in VA Cooperative Study #430: ‘Reducing the Efficacy-Effectiveness Gap in Bipolar Disorder’" @default.
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• W2026464868 cites W1717510248 @default.
• W2026464868 cites W1761627804 @default.
• W2026464868 cites W1968850752 @default.
• W2026464868 cites W1971624262 @default.
• W2026464868 cites W1973433117 @default.
• W2026464868 cites W1975271960 @default.
• W2026464868 cites W1977227623 @default.
• W2026464868 cites W1977870154 @default.
• W2026464868 cites W1979166893 @default.
• W2026464868 cites W198005599 @default.
• W2026464868 cites W1980167446 @default.
• W2026464868 cites W1989464237 @default.
• W2026464868 cites W1997285597 @default.
• W2026464868 cites W1998942924 @default.
• W2026464868 cites W1999464554 @default.
• W2026464868 cites W2001695803 @default.
• W2026464868 cites W2009312581 @default.
• W2026464868 cites W2009927289 @default.
• W2026464868 cites W2016052456 @default.
• W2026464868 cites W2018237572 @default.
• W2026464868 cites W2021182031 @default.
• W2026464868 cites W2025811560 @default.
• W2026464868 cites W2026826487 @default.
• W2026464868 cites W2030855299 @default.
• W2026464868 cites W2033413157 @default.
• W2026464868 cites W2034697959 @default.
• W2026464868 cites W2045687969 @default.
• W2026464868 cites W2048654012 @default.
• W2026464868 cites W2051806956 @default.
• W2026464868 cites W2054484585 @default.
• W2026464868 cites W2060190592 @default.
• W2026464868 cites W2068817959 @default.
• W2026464868 cites W2069887098 @default.
• W2026464868 cites W2069959657 @default.
• W2026464868 cites W2071830609 @default.
• W2026464868 cites W2076758360 @default.
• W2026464868 cites W2080234065 @default.
• W2026464868 cites W2083031898 @default.
• W2026464868 cites W2089091745 @default.
• W2026464868 cites W2092170176 @default.
• W2026464868 cites W2096506809 @default.
• W2026464868 cites W2101318396 @default.
• W2026464868 cites W2102460856 @default.
• W2026464868 cites W2104279565 @default.
• W2026464868 cites W2111388389 @default.
• W2026464868 cites W2112820198 @default.
• W2026464868 cites W2115584738 @default.
• W2026464868 cites W2117556837 @default.
• W2026464868 cites W2124769195 @default.
• W2026464868 cites W2130261986 @default.
• W2026464868 cites W2131936372 @default.
• W2026464868 cites W2137374976 @default.
• W2026464868 cites W2155066293 @default.
• W2026464868 cites W2155180100 @default.
• W2026464868 cites W2159403238 @default.
• W2026464868 cites W2159859896 @default.
• W2026464868 cites W2171185979 @default.
• W2026464868 cites W2177979388 @default.
• W2026464868 cites W2330069695 @default.
• W2026464868 cites W2335691039 @default.
• W2026464868 cites W2338142856 @default.
• W2026464868 cites W2345733617 @default.
• W2026464868 cites W2395095588 @default.
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• W2026464868 cites W4254877772 @default.
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• W2026464868 doi "https://doi.org/10.1016/s0165-0327(01)00440-2" @default.
• W2026464868 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11869753" @default.
• W2026464868 hasPublicationYear "2001" @default.
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