Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026524681> ?p ?o ?g. }
- W2026524681 endingPage "266" @default.
- W2026524681 startingPage "253" @default.
- W2026524681 abstract "A novel series of symmetrically substituted 3,3-dibenzyl-4-hydroxy-3,4-dihydro-1H-quinolin-2-ones was synthesized and tested as antimicrobials. The minimum inhibitory concentration (MIC) values of the most active heterocycles were slightly higher than those exhibited by levofloxacin, employed as comparator. Structural factors affecting the activity were explored along three diversification points, including the substituents of the aromatic rings of the 3-benzyl moieties, as well as the functionalization of both, the homocyclic ring of the heterocycle and the quinolonic nitrogen atom. 6-Chloro and 3,3-bis(4′-chlorobenzyl) derivatives showed the lower MIC values. Optimally substituted heterocycles were synthesized, which exhibited enhanced activity." @default.
- W2026524681 created "2016-06-24" @default.
- W2026524681 creator A5002182058 @default.
- W2026524681 creator A5020255403 @default.
- W2026524681 creator A5026395564 @default.
- W2026524681 creator A5028967934 @default.
- W2026524681 creator A5044450162 @default.
- W2026524681 date "2014-06-01" @default.
- W2026524681 modified "2023-10-09" @default.
- W2026524681 title "Synthesis of symmetrically substituted 3,3-dibenzyl-4-hydroxy-3,4-dihydro-1H-quinolin-2-ones, as novel quinoline derivatives with antibacterial activity" @default.
- W2026524681 cites W1969111642 @default.
- W2026524681 cites W1971188751 @default.
- W2026524681 cites W1971364592 @default.
- W2026524681 cites W1988894485 @default.
- W2026524681 cites W1992217552 @default.
- W2026524681 cites W1993918831 @default.
- W2026524681 cites W1997292923 @default.
- W2026524681 cites W1999307075 @default.
- W2026524681 cites W2000816933 @default.
- W2026524681 cites W2001284093 @default.
- W2026524681 cites W2005194725 @default.
- W2026524681 cites W2005303900 @default.
- W2026524681 cites W2005683797 @default.
- W2026524681 cites W2014605200 @default.
- W2026524681 cites W2014989916 @default.
- W2026524681 cites W2015668673 @default.
- W2026524681 cites W2021497410 @default.
- W2026524681 cites W2027214692 @default.
- W2026524681 cites W2027771387 @default.
- W2026524681 cites W2030526966 @default.
- W2026524681 cites W2031594074 @default.
- W2026524681 cites W2031880511 @default.
- W2026524681 cites W2032430882 @default.
- W2026524681 cites W2035057717 @default.
- W2026524681 cites W2036503873 @default.
- W2026524681 cites W2036576974 @default.
- W2026524681 cites W2038587125 @default.
- W2026524681 cites W2042017868 @default.
- W2026524681 cites W2043055892 @default.
- W2026524681 cites W2044262596 @default.
- W2026524681 cites W2045127125 @default.
- W2026524681 cites W2045614240 @default.
- W2026524681 cites W2048711380 @default.
- W2026524681 cites W2058293146 @default.
- W2026524681 cites W2066404978 @default.
- W2026524681 cites W2068144709 @default.
- W2026524681 cites W2068915554 @default.
- W2026524681 cites W2069292267 @default.
- W2026524681 cites W2070791397 @default.
- W2026524681 cites W2075310280 @default.
- W2026524681 cites W2082019128 @default.
- W2026524681 cites W2086757793 @default.
- W2026524681 cites W2088447274 @default.
- W2026524681 cites W2091950907 @default.
- W2026524681 cites W2094280711 @default.
- W2026524681 cites W2095499904 @default.
- W2026524681 cites W2098615700 @default.
- W2026524681 cites W2101273146 @default.
- W2026524681 cites W2103023476 @default.
- W2026524681 cites W2107230974 @default.
- W2026524681 cites W2108197429 @default.
- W2026524681 cites W2108384965 @default.
- W2026524681 cites W2108604622 @default.
- W2026524681 cites W2109310238 @default.
- W2026524681 cites W2115530270 @default.
- W2026524681 cites W2118063364 @default.
- W2026524681 cites W2124908525 @default.
- W2026524681 cites W2139560724 @default.
- W2026524681 cites W2139845013 @default.
- W2026524681 cites W2140219077 @default.
- W2026524681 cites W2147652807 @default.
- W2026524681 cites W2154136959 @default.
- W2026524681 cites W2170737518 @default.
- W2026524681 cites W2324424520 @default.
- W2026524681 cites W2585579890 @default.
- W2026524681 cites W2949362445 @default.
- W2026524681 cites W2949822999 @default.
- W2026524681 cites W2950363788 @default.
- W2026524681 doi "https://doi.org/10.1016/j.ejmech.2014.05.024" @default.
- W2026524681 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24852274" @default.
- W2026524681 hasPublicationYear "2014" @default.
- W2026524681 type Work @default.
- W2026524681 sameAs 2026524681 @default.
- W2026524681 citedByCount "32" @default.
- W2026524681 countsByYear W20265246812015 @default.
- W2026524681 countsByYear W20265246812016 @default.
- W2026524681 countsByYear W20265246812017 @default.
- W2026524681 countsByYear W20265246812018 @default.
- W2026524681 countsByYear W20265246812019 @default.
- W2026524681 countsByYear W20265246812020 @default.
- W2026524681 countsByYear W20265246812021 @default.
- W2026524681 countsByYear W20265246812022 @default.
- W2026524681 countsByYear W20265246812023 @default.
- W2026524681 crossrefType "journal-article" @default.
- W2026524681 hasAuthorship W2026524681A5002182058 @default.
- W2026524681 hasAuthorship W2026524681A5020255403 @default.
- W2026524681 hasAuthorship W2026524681A5026395564 @default.
- W2026524681 hasAuthorship W2026524681A5028967934 @default.