FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026573527> ?p ?o ?g. }

• W2026573527 endingPage "029501" @default.
• W2026573527 startingPage "029501" @default.
• W2026573527 abstract "Here we fabricate and characterize bioactive composite scaffolds for bone tissue engineering applications. 45S5 Bioglass R © (45S5) or strontium-substituted bioactive glass (SrBG) were incorporated into polycaprolactone (PCL) and fabricated into 3D bioactive composite scaffolds utilizing additive manufacturing technology. We show that composite scaffolds (PCL/45S5 and PCL/SrBG) can be reproducibly manufactured with a scaffold morphology highly resembling that of PCL scaffolds. Additionally, micro-CT analysis reveals BG particles were homogeneously distributed throughout the scaffolds. Mechanical data suggested that PCL/45S5 and PCL/SrBG composite scaffolds have higher compressive Young’s modulus compared to PCL scaffolds at similar porosity (∼75%). After 1 day in accelerated degradation conditions using 5M NaOH, PCL/SrBG, PCL/45S5 and PCL lost 48.6 ± 3.8%, 12.1 ± 1% and 1.6 ± 1% of the original mass, respectively. In vitro studies were conducted using MC3T3 cells under normal and osteogenic conditions. All scaffolds were shown to be non-cytotoxic, and supported cell attachment and proliferation. Our results also indicate that the inclusion of bioactive glass (BG) promotes precipitation of calcium phosphate on the scaffold surfaces which leads to earlier cell differentiation and matrix mineralization when compared to PCL scaffolds. However, as indicated by alkaline phosphatase activity, no significant difference in osteoblast differentiation was found between PCL/45S5 and PCL/SrBG scaffolds. These results suggest that PCL/45S5 and PCL/SrBG composite scaffolds show potential as next generation bone scaffolds. (Some figures may appear in colour only in the online journal)" @default.
• W2026573527 created "2016-06-24" @default.
• W2026573527 creator A5003215109 @default.
• W2026573527 creator A5014672796 @default.
• W2026573527 creator A5080001779 @default.
• W2026573527 creator A5087574116 @default.
• W2026573527 date "2014-04-14" @default.
• W2026573527 modified "2023-09-26" @default.
• W2026573527 title "Corrigendum: Fabrication and <i>in vitro</i> characterization of bioactive glass composite scaffolds for bone regeneration (2013 <i>Biofabrication</i> <b>5</b> 045005)" @default.
• W2026573527 cites W2096898280 @default.
• W2026573527 cites W2126863855 @default.
• W2026573527 doi "https://doi.org/10.1088/1758-5082/6/2/029501" @default.
• W2026573527 hasPublicationYear "2014" @default.
• W2026573527 type Work @default.
• W2026573527 sameAs 2026573527 @default.
• W2026573527 citedByCount "14" @default.
• W2026573527 countsByYear W20265735272014 @default.
• W2026573527 countsByYear W20265735272015 @default.
• W2026573527 countsByYear W20265735272017 @default.
• W2026573527 countsByYear W20265735272018 @default.
• W2026573527 countsByYear W20265735272019 @default.
• W2026573527 countsByYear W20265735272020 @default.
• W2026573527 countsByYear W20265735272022 @default.
• W2026573527 crossrefType "journal-article" @default.
• W2026573527 hasAuthorship W2026573527A5003215109 @default.
• W2026573527 hasAuthorship W2026573527A5014672796 @default.
• W2026573527 hasAuthorship W2026573527A5080001779 @default.
• W2026573527 hasAuthorship W2026573527A5087574116 @default.
• W2026573527 hasBestOaLocation W20265735271 @default.
• W2026573527 hasConcept C104779481 @default.
• W2026573527 hasConcept C136229726 @default.
• W2026573527 hasConcept C136525101 @default.
• W2026573527 hasConcept C142724271 @default.
• W2026573527 hasConcept C159985019 @default.
• W2026573527 hasConcept C171056886 @default.
• W2026573527 hasConcept C171250308 @default.
• W2026573527 hasConcept C185592680 @default.
• W2026573527 hasConcept C192562407 @default.
• W2026573527 hasConcept C202751555 @default.
• W2026573527 hasConcept C204787440 @default.
• W2026573527 hasConcept C2778519171 @default.
• W2026573527 hasConcept C2780609957 @default.
• W2026573527 hasConcept C2780841128 @default.
• W2026573527 hasConcept C49892992 @default.
• W2026573527 hasConcept C55493867 @default.
• W2026573527 hasConcept C71924100 @default.
• W2026573527 hasConcept C86803240 @default.
• W2026573527 hasConcept C95444343 @default.
• W2026573527 hasConceptScore W2026573527C104779481 @default.
• W2026573527 hasConceptScore W2026573527C136229726 @default.
• W2026573527 hasConceptScore W2026573527C136525101 @default.
• W2026573527 hasConceptScore W2026573527C142724271 @default.
• W2026573527 hasConceptScore W2026573527C159985019 @default.
• W2026573527 hasConceptScore W2026573527C171056886 @default.
• W2026573527 hasConceptScore W2026573527C171250308 @default.
• W2026573527 hasConceptScore W2026573527C185592680 @default.
• W2026573527 hasConceptScore W2026573527C192562407 @default.
• W2026573527 hasConceptScore W2026573527C202751555 @default.
• W2026573527 hasConceptScore W2026573527C204787440 @default.
• W2026573527 hasConceptScore W2026573527C2778519171 @default.
• W2026573527 hasConceptScore W2026573527C2780609957 @default.
• W2026573527 hasConceptScore W2026573527C2780841128 @default.
• W2026573527 hasConceptScore W2026573527C49892992 @default.
• W2026573527 hasConceptScore W2026573527C55493867 @default.
• W2026573527 hasConceptScore W2026573527C71924100 @default.
• W2026573527 hasConceptScore W2026573527C86803240 @default.
• W2026573527 hasConceptScore W2026573527C95444343 @default.
• W2026573527 hasIssue "2" @default.
• W2026573527 hasLocation W20265735271 @default.
• W2026573527 hasOpenAccess W2026573527 @default.
• W2026573527 hasPrimaryLocation W20265735271 @default.
• W2026573527 hasRelatedWork W2005496670 @default.
• W2026573527 hasRelatedWork W2082293200 @default.
• W2026573527 hasRelatedWork W2137307547 @default.
• W2026573527 hasRelatedWork W2380293314 @default.
• W2026573527 hasRelatedWork W2479038466 @default.
• W2026573527 hasRelatedWork W2619507405 @default.
• W2026573527 hasRelatedWork W2943188944 @default.
• W2026573527 hasRelatedWork W3048672776 @default.
• W2026573527 hasRelatedWork W3082440218 @default.
• W2026573527 hasRelatedWork W4285802202 @default.
• W2026573527 hasVolume "6" @default.
• W2026573527 isParatext "false" @default.
• W2026573527 isRetracted "false" @default.
• W2026573527 magId "2026573527" @default.
• W2026573527 workType "article" @default.