FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026579654> ?p ?o ?g. }

• W2026579654 endingPage "2953" @default.
• W2026579654 startingPage "2947" @default.
• W2026579654 abstract "Ferritins from microorganisms to man are known to contain varying amounts of phosphate which has a pronounced effect on the structural and magnetic properties of their iron mineral cores. The present study was undertaken to gain insight into the role of phosphate in the early stages of iron accumulation by ferritin. The influence of phosphate on the initial deposition of iron in apoferritin (12 Fe/protein) was investigated by EPR, 57Fe Mössbauer spectroscopy, and equilibrium dialysis. The results indicate that phosphate has a significant influence on iron deposition. The presence of 1 mM phosphate during reconstitution of ferritin from apoferritin, Fe(II), and O2 accelerates the rate of oxidation of the iron 2-fold at pH 7.5. In the presence or absence of phosphate, the rate of oxidation at 0 degrees C follows simple first-order kinetics with respect to Fe(II) with half-lives of 1.5 +/- 0.3 or 2.8 +/- 0.2 min, respectively, consistent with a single pathway for iron oxidation when low levels of iron are added to the apoprotein. This pathway may involve a protein ferroxidase site where phosphate may bind iron(II), shifting its redox potential to a more negative value and thus facilitating its oxidation. Following oxidation, an intermediate mononuclear Fe(III)-protein complex is formed which exhibits a transient EPR signal at g' = 4.3. Phosphate accelerates the rate of decay of the signal by a factor of 3-4, producing EPR-silent oligonuclear or polynuclear Fe(III) clusters. In 0.5 mM Pi, the signal decays according to a single phase first-order process with a half-life near 1 min.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2026579654 created "2016-06-24" @default.
• W2026579654 creator A5030409732 @default.
• W2026579654 creator A5056671277 @default.
• W2026579654 date "1991-03-19" @default.
• W2026579654 modified "2023-09-26" @default.
• W2026579654 title "Role of phosphate in initial iron deposition in apoferritin" @default.
• W2026579654 cites W1486686751 @default.
• W2026579654 cites W1501427854 @default.
• W2026579654 cites W1520572643 @default.
• W2026579654 cites W1540335395 @default.
• W2026579654 cites W1545086647 @default.
• W2026579654 cites W1610265054 @default.
• W2026579654 cites W188669543 @default.
• W2026579654 cites W1979635074 @default.
• W2026579654 cites W1982216387 @default.
• W2026579654 cites W1987119816 @default.
• W2026579654 cites W1993798891 @default.
• W2026579654 cites W2002189548 @default.
• W2026579654 cites W2046903482 @default.
• W2026579654 cites W2050581004 @default.
• W2026579654 cites W2055869951 @default.
• W2026579654 cites W2060621094 @default.
• W2026579654 cites W2062220603 @default.
• W2026579654 cites W2065080919 @default.
• W2026579654 cites W2068225953 @default.
• W2026579654 cites W2069314445 @default.
• W2026579654 cites W2074206586 @default.
• W2026579654 cites W2076190961 @default.
• W2026579654 cites W2081465711 @default.
• W2026579654 cites W2087344937 @default.
• W2026579654 cites W2087386233 @default.
• W2026579654 cites W2090090513 @default.
• W2026579654 cites W2091913250 @default.
• W2026579654 cites W2092818123 @default.
• W2026579654 cites W2153839710 @default.
• W2026579654 cites W2156605690 @default.
• W2026579654 cites W2344967257 @default.
• W2026579654 cites W2396000603 @default.
• W2026579654 cites W964266781 @default.
• W2026579654 doi "https://doi.org/10.1021/bi00225a031" @default.
• W2026579654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2007131" @default.
• W2026579654 hasPublicationYear "1991" @default.
• W2026579654 type Work @default.
• W2026579654 sameAs 2026579654 @default.
• W2026579654 citedByCount "50" @default.
• W2026579654 countsByYear W20265796542013 @default.
• W2026579654 countsByYear W20265796542018 @default.
• W2026579654 countsByYear W20265796542019 @default.
• W2026579654 countsByYear W20265796542020 @default.
• W2026579654 countsByYear W20265796542022 @default.
• W2026579654 crossrefType "journal-article" @default.
• W2026579654 hasAuthorship W2026579654A5030409732 @default.
• W2026579654 hasAuthorship W2026579654A5056671277 @default.
• W2026579654 hasConcept C121332964 @default.
• W2026579654 hasConcept C148898269 @default.
• W2026579654 hasConcept C179104552 @default.
• W2026579654 hasConcept C185592680 @default.
• W2026579654 hasConcept C187961010 @default.
• W2026579654 hasConcept C2777132085 @default.
• W2026579654 hasConcept C2778319317 @default.
• W2026579654 hasConcept C2778620993 @default.
• W2026579654 hasConcept C28452662 @default.
• W2026579654 hasConcept C46141821 @default.
• W2026579654 hasConcept C55493867 @default.
• W2026579654 hasConcept C55904794 @default.
• W2026579654 hasConcept C62520636 @default.
• W2026579654 hasConceptScore W2026579654C121332964 @default.
• W2026579654 hasConceptScore W2026579654C148898269 @default.
• W2026579654 hasConceptScore W2026579654C179104552 @default.
• W2026579654 hasConceptScore W2026579654C185592680 @default.
• W2026579654 hasConceptScore W2026579654C187961010 @default.
• W2026579654 hasConceptScore W2026579654C2777132085 @default.
• W2026579654 hasConceptScore W2026579654C2778319317 @default.
• W2026579654 hasConceptScore W2026579654C2778620993 @default.
• W2026579654 hasConceptScore W2026579654C28452662 @default.
• W2026579654 hasConceptScore W2026579654C46141821 @default.
• W2026579654 hasConceptScore W2026579654C55493867 @default.
• W2026579654 hasConceptScore W2026579654C55904794 @default.
• W2026579654 hasConceptScore W2026579654C62520636 @default.
• W2026579654 hasIssue "11" @default.
• W2026579654 hasLocation W20265796541 @default.
• W2026579654 hasLocation W20265796542 @default.
• W2026579654 hasOpenAccess W2026579654 @default.
• W2026579654 hasPrimaryLocation W20265796541 @default.
• W2026579654 hasRelatedWork W2036234641 @default.
• W2026579654 hasRelatedWork W2041865621 @default.
• W2026579654 hasRelatedWork W2046958130 @default.
• W2026579654 hasRelatedWork W2056164057 @default.
• W2026579654 hasRelatedWork W2061484893 @default.
• W2026579654 hasRelatedWork W2091544255 @default.
• W2026579654 hasRelatedWork W2119023262 @default.
• W2026579654 hasRelatedWork W2364476463 @default.
• W2026579654 hasRelatedWork W2387117274 @default.
• W2026579654 hasRelatedWork W4250194437 @default.
• W2026579654 hasVolume "30" @default.
• W2026579654 isParatext "false" @default.
• W2026579654 isRetracted "false" @default.

• next