FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026596113> ?p ?o ?g. }

• W2026596113 endingPage "S202" @default.
• W2026596113 startingPage "S202" @default.
• W2026596113 abstract "Purpose/Objective(s)To evaluate the effect of the surgery-radiotherapy interval (SRI) on local control in node-negative breast cancer patients treated with breast conserving surgery and adjuvant radiotherapy without chemotherapy.Materials/MethodsFrom February 1992 to January 2002, 171 patients with node-negative breast cancer underwent breast conserving surgery and adjuvant radiotherapy without chemotherapy. Whole breast was irradiated up to 50.4 Gy in 28 fractions followed by 10 Gy boost to tumor bed. Forty-nine patients received tamoxifen, as well. Patients were divided into 2 groups according to SRI: SRI <6 wks (128 patients) versus SRI ≥6 wks (43 patients). Median follow-up period was 87 months (range; 22-167).ResultsThe 8-year local control rates of patients with SRI <6 wks and ≥6 wks were 94.5% and 92.7%, respectively (p = 0.1140). When age, tumor size, resection margin status, the combination of hormonal therapy, and SRI were incorporated into Cox proportional hazard model, SRI <6 wks and age at diagnosis ≥40 yrs were associated with increased local control (p = 0.0343 and 0.0264, respectively). In the subgroup analysis, SRI <6 wks was correlated with higher local control rate for patients younger than 40 yrs (p = 0.0142). Among older patients, however, there was no statistical difference of local control according to SRI (p = 0.6655). Treatment interval had no impact on overall and distant metastasis-free survival.ConclusionsEarly radiotherapy within 6 wks after breast conserving surgery is associated with increased local control in patients with node-negative breast cancer not undergoing chemotherapy, especially in patients younger than 40 yrs old. Earlier treatment should be considered in this group of patients. Purpose/Objective(s)To evaluate the effect of the surgery-radiotherapy interval (SRI) on local control in node-negative breast cancer patients treated with breast conserving surgery and adjuvant radiotherapy without chemotherapy. To evaluate the effect of the surgery-radiotherapy interval (SRI) on local control in node-negative breast cancer patients treated with breast conserving surgery and adjuvant radiotherapy without chemotherapy. Materials/MethodsFrom February 1992 to January 2002, 171 patients with node-negative breast cancer underwent breast conserving surgery and adjuvant radiotherapy without chemotherapy. Whole breast was irradiated up to 50.4 Gy in 28 fractions followed by 10 Gy boost to tumor bed. Forty-nine patients received tamoxifen, as well. Patients were divided into 2 groups according to SRI: SRI <6 wks (128 patients) versus SRI ≥6 wks (43 patients). Median follow-up period was 87 months (range; 22-167). From February 1992 to January 2002, 171 patients with node-negative breast cancer underwent breast conserving surgery and adjuvant radiotherapy without chemotherapy. Whole breast was irradiated up to 50.4 Gy in 28 fractions followed by 10 Gy boost to tumor bed. Forty-nine patients received tamoxifen, as well. Patients were divided into 2 groups according to SRI: SRI <6 wks (128 patients) versus SRI ≥6 wks (43 patients). Median follow-up period was 87 months (range; 22-167). ResultsThe 8-year local control rates of patients with SRI <6 wks and ≥6 wks were 94.5% and 92.7%, respectively (p = 0.1140). When age, tumor size, resection margin status, the combination of hormonal therapy, and SRI were incorporated into Cox proportional hazard model, SRI <6 wks and age at diagnosis ≥40 yrs were associated with increased local control (p = 0.0343 and 0.0264, respectively). In the subgroup analysis, SRI <6 wks was correlated with higher local control rate for patients younger than 40 yrs (p = 0.0142). Among older patients, however, there was no statistical difference of local control according to SRI (p = 0.6655). Treatment interval had no impact on overall and distant metastasis-free survival. The 8-year local control rates of patients with SRI <6 wks and ≥6 wks were 94.5% and 92.7%, respectively (p = 0.1140). When age, tumor size, resection margin status, the combination of hormonal therapy, and SRI were incorporated into Cox proportional hazard model, SRI <6 wks and age at diagnosis ≥40 yrs were associated with increased local control (p = 0.0343 and 0.0264, respectively). In the subgroup analysis, SRI <6 wks was correlated with higher local control rate for patients younger than 40 yrs (p = 0.0142). Among older patients, however, there was no statistical difference of local control according to SRI (p = 0.6655). Treatment interval had no impact on overall and distant metastasis-free survival. ConclusionsEarly radiotherapy within 6 wks after breast conserving surgery is associated with increased local control in patients with node-negative breast cancer not undergoing chemotherapy, especially in patients younger than 40 yrs old. Earlier treatment should be considered in this group of patients. Early radiotherapy within 6 wks after breast conserving surgery is associated with increased local control in patients with node-negative breast cancer not undergoing chemotherapy, especially in patients younger than 40 yrs old. Earlier treatment should be considered in this group of patients." @default.
• W2026596113 created "2016-06-24" @default.
• W2026596113 creator A5005022842 @default.
• W2026596113 creator A5013664294 @default.
• W2026596113 creator A5018868292 @default.
• W2026596113 creator A5049125652 @default.
• W2026596113 creator A5062459156 @default.
• W2026596113 creator A5089784777 @default.
• W2026596113 date "2009-11-01" @default.
• W2026596113 modified "2023-10-16" @default.
• W2026596113 title "Impact of Delayed Radiotherapy on Local Control in Node-negative Breast Cancer Patients Treated with Breast Conserving Surgery and Adjuvant Radiotherapy without Chemotherapy" @default.
• W2026596113 cites W1977536988 @default.
• W2026596113 cites W1979300931 @default.
• W2026596113 cites W2000926931 @default.
• W2026596113 cites W2001431530 @default.
• W2026596113 cites W2010831895 @default.
• W2026596113 cites W2018568783 @default.
• W2026596113 cites W2044138832 @default.
• W2026596113 cites W2047375857 @default.
• W2026596113 cites W2052230111 @default.
• W2026596113 cites W2063327753 @default.
• W2026596113 cites W2066920146 @default.
• W2026596113 cites W2070388789 @default.
• W2026596113 cites W2145863615 @default.
• W2026596113 cites W2167952584 @default.
• W2026596113 cites W2169031890 @default.
• W2026596113 doi "https://doi.org/10.1016/j.ijrobp.2009.07.468" @default.
• W2026596113 hasPublicationYear "2009" @default.
• W2026596113 type Work @default.
• W2026596113 sameAs 2026596113 @default.
• W2026596113 citedByCount "0" @default.
• W2026596113 crossrefType "journal-article" @default.
• W2026596113 hasAuthorship W2026596113A5005022842 @default.
• W2026596113 hasAuthorship W2026596113A5013664294 @default.
• W2026596113 hasAuthorship W2026596113A5018868292 @default.
• W2026596113 hasAuthorship W2026596113A5049125652 @default.
• W2026596113 hasAuthorship W2026596113A5062459156 @default.
• W2026596113 hasAuthorship W2026596113A5089784777 @default.
• W2026596113 hasBestOaLocation W20265961131 @default.
• W2026596113 hasConcept C121608353 @default.
• W2026596113 hasConcept C126322002 @default.
• W2026596113 hasConcept C141071460 @default.
• W2026596113 hasConcept C143998085 @default.
• W2026596113 hasConcept C146357865 @default.
• W2026596113 hasConcept C151730666 @default.
• W2026596113 hasConcept C207103383 @default.
• W2026596113 hasConcept C2776694085 @default.
• W2026596113 hasConcept C2777176818 @default.
• W2026596113 hasConcept C2777757722 @default.
• W2026596113 hasConcept C2781467025 @default.
• W2026596113 hasConcept C44249647 @default.
• W2026596113 hasConcept C509974204 @default.
• W2026596113 hasConcept C530470458 @default.
• W2026596113 hasConcept C71924100 @default.
• W2026596113 hasConcept C86803240 @default.
• W2026596113 hasConceptScore W2026596113C121608353 @default.
• W2026596113 hasConceptScore W2026596113C126322002 @default.
• W2026596113 hasConceptScore W2026596113C141071460 @default.
• W2026596113 hasConceptScore W2026596113C143998085 @default.
• W2026596113 hasConceptScore W2026596113C146357865 @default.
• W2026596113 hasConceptScore W2026596113C151730666 @default.
• W2026596113 hasConceptScore W2026596113C207103383 @default.
• W2026596113 hasConceptScore W2026596113C2776694085 @default.
• W2026596113 hasConceptScore W2026596113C2777176818 @default.
• W2026596113 hasConceptScore W2026596113C2777757722 @default.
• W2026596113 hasConceptScore W2026596113C2781467025 @default.
• W2026596113 hasConceptScore W2026596113C44249647 @default.
• W2026596113 hasConceptScore W2026596113C509974204 @default.
• W2026596113 hasConceptScore W2026596113C530470458 @default.
• W2026596113 hasConceptScore W2026596113C71924100 @default.
• W2026596113 hasConceptScore W2026596113C86803240 @default.
• W2026596113 hasIssue "3" @default.
• W2026596113 hasLocation W20265961131 @default.
• W2026596113 hasOpenAccess W2026596113 @default.
• W2026596113 hasPrimaryLocation W20265961131 @default.
• W2026596113 hasRelatedWork W1970677298 @default.
• W2026596113 hasRelatedWork W2009869235 @default.
• W2026596113 hasRelatedWork W2049566046 @default.
• W2026596113 hasRelatedWork W2057553101 @default.
• W2026596113 hasRelatedWork W2091599823 @default.
• W2026596113 hasRelatedWork W2106734666 @default.
• W2026596113 hasRelatedWork W2161568138 @default.
• W2026596113 hasRelatedWork W2462066450 @default.
• W2026596113 hasRelatedWork W2759031936 @default.
• W2026596113 hasRelatedWork W3029766897 @default.
• W2026596113 hasVolume "75" @default.
• W2026596113 isParatext "false" @default.
• W2026596113 isRetracted "false" @default.
• W2026596113 magId "2026596113" @default.
• W2026596113 workType "article" @default.