Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026599042> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2026599042 endingPage "e40" @default.
- W2026599042 startingPage "e37" @default.
- W2026599042 abstract "Molecular testing is the current standard of care for nonesmall-cell lung cancer particularly adenocarcinoma (ADC). Novel tyrosine kinase inhibitors are currently available to target aberrations in epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) in these tumors. Often, this testing is performed using diagnostic fine needle aspiration (FNA) or core biopsy. Pathologists use immunohistochemistry to identify biomarkers to distinguish histologic types and to triage tumors for molecular studies. Here, we report a case of an adenosquamous carcinoma initially diagnosed as a squamous cell carcinoma in a FNA biopsy that was found on resection to have an ADC component and harbor an ALK rearrangement. Using current guidelines, this ALK rearrangement might have not been identified and the patient would not have been considered for crizotinib therapy. A small biopsy might not be representative of a lung cancer with mixed histologies; in instances when an ADC component cannot be excluded, testing for EGFR or ALK might be warranted and clinical criteria could be used to select patients for testing." @default.
- W2026599042 created "2016-06-24" @default.
- W2026599042 creator A5017932012 @default.
- W2026599042 creator A5040432994 @default.
- W2026599042 creator A5049504429 @default.
- W2026599042 creator A5052728393 @default.
- W2026599042 date "2014-05-01" @default.
- W2026599042 modified "2023-10-07" @default.
- W2026599042 title "ALK-Rearranged Adenosquamous Lung Cancer Presenting as Squamous Cell Carcinoma: A Potential Challenge to Histologic Type Triaging of NSCLC Biopsies for Molecular Studies" @default.
- W2026599042 cites W1974410799 @default.
- W2026599042 cites W1978236936 @default.
- W2026599042 cites W1982267649 @default.
- W2026599042 cites W2002960454 @default.
- W2026599042 cites W2009178666 @default.
- W2026599042 cites W2013733453 @default.
- W2026599042 cites W2015984642 @default.
- W2026599042 cites W2025156982 @default.
- W2026599042 cites W2028501011 @default.
- W2026599042 cites W2031494655 @default.
- W2026599042 cites W2069455693 @default.
- W2026599042 cites W2091312158 @default.
- W2026599042 cites W2119994930 @default.
- W2026599042 cites W2125514375 @default.
- W2026599042 cites W2156454208 @default.
- W2026599042 cites W2170744484 @default.
- W2026599042 cites W2329625383 @default.
- W2026599042 doi "https://doi.org/10.1016/j.cllc.2014.01.003" @default.
- W2026599042 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24524823" @default.
- W2026599042 hasPublicationYear "2014" @default.
- W2026599042 type Work @default.
- W2026599042 sameAs 2026599042 @default.
- W2026599042 citedByCount "14" @default.
- W2026599042 countsByYear W20265990422014 @default.
- W2026599042 countsByYear W20265990422015 @default.
- W2026599042 countsByYear W20265990422016 @default.
- W2026599042 countsByYear W20265990422018 @default.
- W2026599042 countsByYear W20265990422019 @default.
- W2026599042 countsByYear W20265990422021 @default.
- W2026599042 countsByYear W20265990422022 @default.
- W2026599042 countsByYear W20265990422023 @default.
- W2026599042 crossrefType "journal-article" @default.
- W2026599042 hasAuthorship W2026599042A5017932012 @default.
- W2026599042 hasAuthorship W2026599042A5040432994 @default.
- W2026599042 hasAuthorship W2026599042A5049504429 @default.
- W2026599042 hasAuthorship W2026599042A5052728393 @default.
- W2026599042 hasConcept C121608353 @default.
- W2026599042 hasConcept C126322002 @default.
- W2026599042 hasConcept C142724271 @default.
- W2026599042 hasConcept C143998085 @default.
- W2026599042 hasConcept C2776256026 @default.
- W2026599042 hasConcept C2776512503 @default.
- W2026599042 hasConcept C2777546739 @default.
- W2026599042 hasConcept C2781182431 @default.
- W2026599042 hasConcept C3019992690 @default.
- W2026599042 hasConcept C502942594 @default.
- W2026599042 hasConcept C71924100 @default.
- W2026599042 hasConceptScore W2026599042C121608353 @default.
- W2026599042 hasConceptScore W2026599042C126322002 @default.
- W2026599042 hasConceptScore W2026599042C142724271 @default.
- W2026599042 hasConceptScore W2026599042C143998085 @default.
- W2026599042 hasConceptScore W2026599042C2776256026 @default.
- W2026599042 hasConceptScore W2026599042C2776512503 @default.
- W2026599042 hasConceptScore W2026599042C2777546739 @default.
- W2026599042 hasConceptScore W2026599042C2781182431 @default.
- W2026599042 hasConceptScore W2026599042C3019992690 @default.
- W2026599042 hasConceptScore W2026599042C502942594 @default.
- W2026599042 hasConceptScore W2026599042C71924100 @default.
- W2026599042 hasIssue "3" @default.
- W2026599042 hasLocation W20265990421 @default.
- W2026599042 hasLocation W20265990422 @default.
- W2026599042 hasOpenAccess W2026599042 @default.
- W2026599042 hasPrimaryLocation W20265990421 @default.
- W2026599042 hasRelatedWork W1748335368 @default.
- W2026599042 hasRelatedWork W1964681864 @default.
- W2026599042 hasRelatedWork W2018380129 @default.
- W2026599042 hasRelatedWork W2070385249 @default.
- W2026599042 hasRelatedWork W2093736401 @default.
- W2026599042 hasRelatedWork W2359279895 @default.
- W2026599042 hasRelatedWork W2473322630 @default.
- W2026599042 hasRelatedWork W2475257193 @default.
- W2026599042 hasRelatedWork W2962961055 @default.
- W2026599042 hasRelatedWork W2150001289 @default.
- W2026599042 hasVolume "15" @default.
- W2026599042 isParatext "false" @default.
- W2026599042 isRetracted "false" @default.
- W2026599042 magId "2026599042" @default.
- W2026599042 workType "article" @default.