Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026621036> ?p ?o ?g. }
- W2026621036 endingPage "487" @default.
- W2026621036 startingPage "476" @default.
- W2026621036 abstract "Methicillin-resistant Staphylococcus aureus is an increasingly important cause of nosocomial bacterial infections worldwide. S. aureus is responsible for several pathologies, including skin infections, endocarditis, meningitis, deep-tissue ulcers, and sepsis. S. aureus biofilm formation on catheters and other medical devices is a major post-operative concern, because biofilms are often the source of persistent and difficult to treat bacterial infections. While catheter-related S. aureus infections have been reported, the strains responsible for these infections have not been genetically characterized. We genetically characterized S. aureus strains isolated from hemodialysis catheters in Mexican patients. The frequency of 35 genes coding for adhesins, toxins, and other virulence-associated products in the 55 isolated S. aureus strains was determined using PCR, while real-time PCR was used to examine the level of gene expression. Of the 55 S. aureus strains isolated from 109 patients, 45 (81.8%) were determined to be methicillin-resistant. The icaA, rbf, sarA, and agr genes are involved in biofilm formation and bacterial dispersion and were detected in 96.3%, 40.0%, 74.5%, and 100% of S. aureus strains, respectively, and 70.9% of the strains formed a detectable biofilm. Interestingly, 67.2% of the strains contained the icaA, agr, spa, clfA, sdrC, sdrD, sdrE, seg, seh, and sei genes, suggesting that this gene combination is important for successful catheter colonization. The results of this study provide significant insight into the virulence gene make-up of catheter-colonizing S. aureus strains, and will assist in developing a more targeted treatment approach for persistent S. aureus biofilm contamination of medical devices." @default.
- W2026621036 created "2016-06-24" @default.
- W2026621036 creator A5009466489 @default.
- W2026621036 creator A5043463772 @default.
- W2026621036 creator A5043843937 @default.
- W2026621036 creator A5054809536 @default.
- W2026621036 creator A5059866696 @default.
- W2026621036 creator A5079640524 @default.
- W2026621036 creator A5083905106 @default.
- W2026621036 date "2012-01-01" @default.
- W2026621036 modified "2023-10-18" @default.
- W2026621036 title "Virulence Markers in <i>Staphylococcus aureus</i> Strains Isolated from Hemodialysis Catheters of Mexican Patients" @default.
- W2026621036 cites W1866282443 @default.
- W2026621036 cites W1965809073 @default.
- W2026621036 cites W1974668730 @default.
- W2026621036 cites W1991334413 @default.
- W2026621036 cites W1995729033 @default.
- W2026621036 cites W2008053020 @default.
- W2026621036 cites W2015400027 @default.
- W2026621036 cites W2023630011 @default.
- W2026621036 cites W2031188173 @default.
- W2026621036 cites W2033719139 @default.
- W2026621036 cites W2037918377 @default.
- W2026621036 cites W2047070344 @default.
- W2026621036 cites W2071123327 @default.
- W2026621036 cites W2073287858 @default.
- W2026621036 cites W2087937367 @default.
- W2026621036 cites W2087967982 @default.
- W2026621036 cites W2091364075 @default.
- W2026621036 cites W2093675450 @default.
- W2026621036 cites W2102360445 @default.
- W2026621036 cites W2103312297 @default.
- W2026621036 cites W2108754827 @default.
- W2026621036 cites W2112785877 @default.
- W2026621036 cites W2113426539 @default.
- W2026621036 cites W2117160013 @default.
- W2026621036 cites W2119011878 @default.
- W2026621036 cites W2121897239 @default.
- W2026621036 cites W2134508800 @default.
- W2026621036 cites W2170024040 @default.
- W2026621036 doi "https://doi.org/10.4236/aim.2012.24061" @default.
- W2026621036 hasPublicationYear "2012" @default.
- W2026621036 type Work @default.
- W2026621036 sameAs 2026621036 @default.
- W2026621036 citedByCount "22" @default.
- W2026621036 countsByYear W20266210362013 @default.
- W2026621036 countsByYear W20266210362014 @default.
- W2026621036 countsByYear W20266210362016 @default.
- W2026621036 countsByYear W20266210362017 @default.
- W2026621036 countsByYear W20266210362018 @default.
- W2026621036 countsByYear W20266210362019 @default.
- W2026621036 countsByYear W20266210362020 @default.
- W2026621036 countsByYear W20266210362021 @default.
- W2026621036 countsByYear W20266210362023 @default.
- W2026621036 crossrefType "journal-article" @default.
- W2026621036 hasAuthorship W2026621036A5009466489 @default.
- W2026621036 hasAuthorship W2026621036A5043463772 @default.
- W2026621036 hasAuthorship W2026621036A5043843937 @default.
- W2026621036 hasAuthorship W2026621036A5054809536 @default.
- W2026621036 hasAuthorship W2026621036A5059866696 @default.
- W2026621036 hasAuthorship W2026621036A5079640524 @default.
- W2026621036 hasAuthorship W2026621036A5083905106 @default.
- W2026621036 hasBestOaLocation W20266210361 @default.
- W2026621036 hasConcept C104317684 @default.
- W2026621036 hasConcept C179470777 @default.
- W2026621036 hasConcept C203014093 @default.
- W2026621036 hasConcept C2777334864 @default.
- W2026621036 hasConcept C2778384902 @default.
- W2026621036 hasConcept C2779489039 @default.
- W2026621036 hasConcept C523546767 @default.
- W2026621036 hasConcept C54355233 @default.
- W2026621036 hasConcept C55493867 @default.
- W2026621036 hasConcept C58123911 @default.
- W2026621036 hasConcept C60987743 @default.
- W2026621036 hasConcept C86803240 @default.
- W2026621036 hasConcept C89423630 @default.
- W2026621036 hasConceptScore W2026621036C104317684 @default.
- W2026621036 hasConceptScore W2026621036C179470777 @default.
- W2026621036 hasConceptScore W2026621036C203014093 @default.
- W2026621036 hasConceptScore W2026621036C2777334864 @default.
- W2026621036 hasConceptScore W2026621036C2778384902 @default.
- W2026621036 hasConceptScore W2026621036C2779489039 @default.
- W2026621036 hasConceptScore W2026621036C523546767 @default.
- W2026621036 hasConceptScore W2026621036C54355233 @default.
- W2026621036 hasConceptScore W2026621036C55493867 @default.
- W2026621036 hasConceptScore W2026621036C58123911 @default.
- W2026621036 hasConceptScore W2026621036C60987743 @default.
- W2026621036 hasConceptScore W2026621036C86803240 @default.
- W2026621036 hasConceptScore W2026621036C89423630 @default.
- W2026621036 hasIssue "04" @default.
- W2026621036 hasLocation W20266210361 @default.
- W2026621036 hasOpenAccess W2026621036 @default.
- W2026621036 hasPrimaryLocation W20266210361 @default.
- W2026621036 hasRelatedWork W1970984238 @default.
- W2026621036 hasRelatedWork W1994707247 @default.
- W2026621036 hasRelatedWork W2087552300 @default.
- W2026621036 hasRelatedWork W2130763979 @default.
- W2026621036 hasRelatedWork W2332685989 @default.