FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026707917> ?p ?o ?g. }

• W2026707917 endingPage "24" @default.
• W2026707917 startingPage "10" @default.
• W2026707917 abstract "β-blockers are the first-line therapeutic agents for treating cardiovascular diseases and also a class of prohibited substances in athletic competitions. In this work, a smart strategy that combines three-way liquid chromatography–mass spectrometry (LC–MS) data with second-order calibration method based on alternating trilinear decomposition (ATLD) algorithm was developed for simultaneous determination of ten β-blockers in human urine and plasma samples. This flexible strategy proved to be a useful tool to solve the problems of overlapped peaks and uncalibrated interferences encountered in quantitative LC–MS, and made the multi-targeted interference-free qualitative and quantitative analysis of β-blockers in complex matrices possible. The limits of detection were in the range of 2.0 × 10−5–6.2 × 10−3 μg mL−1, and the average recoveries were between 90 and 110% with standard deviations and average relative prediction errors less than 10%, indicating that the strategy could provide satisfactory prediction results for ten β-blockers in human urine and plasma samples only using liquid chromatography hyphenated single–quadrupole mass spectrometer in full scan mode. To further confirm the feasibility and reliability of the proposed method, the same batch samples were analyzed by multiple reaction monitoring (MRM) method. T-test demonstrated that there are no significant differences between the prediction results of the two methods. Considering the advantages of fast, low-cost, high sensitivity, and no need of complicated chromatographic and tandem mass spectrometric conditions optimization, the proposed strategy is expected to be extended as an attractive alternative method to quantify analyte(s) of interest in complex systems such as cells, biological fluids, food, environment, pharmaceuticals and other complex samples." @default.
• W2026707917 created "2016-06-24" @default.
• W2026707917 creator A5011547109 @default.
• W2026707917 creator A5013054784 @default.
• W2026707917 creator A5029843517 @default.
• W2026707917 creator A5031502955 @default.
• W2026707917 creator A5031777663 @default.
• W2026707917 creator A5038528725 @default.
• W2026707917 creator A5046881907 @default.
• W2026707917 creator A5047135919 @default.
• W2026707917 creator A5057539657 @default.
• W2026707917 creator A5067057402 @default.
• W2026707917 creator A5071530636 @default.
• W2026707917 creator A5072580346 @default.
• W2026707917 date "2014-10-01" @default.
• W2026707917 modified "2023-10-15" @default.
• W2026707917 title "Multi-targeted interference-free determination of ten β-blockers in human urine and plasma samples by alternating trilinear decomposition algorithm-assisted liquid chromatography–mass spectrometry in full scan mode: Comparison with multiple reaction monitoring" @default.
• W2026707917 cites W1504006766 @default.
• W2026707917 cites W1541417542 @default.
• W2026707917 cites W1964121443 @default.
• W2026707917 cites W1964829577 @default.
• W2026707917 cites W1967787298 @default.
• W2026707917 cites W1969328859 @default.
• W2026707917 cites W1970207974 @default.
• W2026707917 cites W1970499519 @default.
• W2026707917 cites W1973268396 @default.
• W2026707917 cites W1978721413 @default.
• W2026707917 cites W1980504885 @default.
• W2026707917 cites W1984053258 @default.
• W2026707917 cites W1984259768 @default.
• W2026707917 cites W1984638142 @default.
• W2026707917 cites W1985858551 @default.
• W2026707917 cites W1996535019 @default.
• W2026707917 cites W1997081812 @default.
• W2026707917 cites W1997735390 @default.
• W2026707917 cites W1997778761 @default.
• W2026707917 cites W1999517677 @default.
• W2026707917 cites W1999712064 @default.
• W2026707917 cites W2006065087 @default.
• W2026707917 cites W2017023866 @default.
• W2026707917 cites W2017552160 @default.
• W2026707917 cites W2017573339 @default.
• W2026707917 cites W2017886620 @default.
• W2026707917 cites W2019868759 @default.
• W2026707917 cites W2023286685 @default.
• W2026707917 cites W2026062301 @default.
• W2026707917 cites W2027898208 @default.
• W2026707917 cites W2029248762 @default.
• W2026707917 cites W2030263603 @default.
• W2026707917 cites W2032117051 @default.
• W2026707917 cites W2038614908 @default.
• W2026707917 cites W2042712923 @default.
• W2026707917 cites W2044373039 @default.
• W2026707917 cites W2046772800 @default.
• W2026707917 cites W2047328214 @default.
• W2026707917 cites W2047680880 @default.
• W2026707917 cites W2049048974 @default.
• W2026707917 cites W2049924881 @default.
• W2026707917 cites W2052775306 @default.
• W2026707917 cites W2065104900 @default.
• W2026707917 cites W2066926844 @default.
• W2026707917 cites W2069753895 @default.
• W2026707917 cites W2071029974 @default.
• W2026707917 cites W2079860161 @default.
• W2026707917 cites W2084814453 @default.
• W2026707917 cites W2093512816 @default.
• W2026707917 cites W2093767384 @default.
• W2026707917 cites W2096975486 @default.
• W2026707917 cites W2102714696 @default.
• W2026707917 cites W2106376891 @default.
• W2026707917 cites W2119741678 @default.
• W2026707917 cites W2136282086 @default.
• W2026707917 cites W2145705669 @default.
• W2026707917 cites W2146938689 @default.
• W2026707917 cites W2158932271 @default.
• W2026707917 cites W2167838035 @default.
• W2026707917 cites W2334253103 @default.
• W2026707917 cites W2335684698 @default.
• W2026707917 cites W2917462181 @default.
• W2026707917 cites W7687383 @default.
• W2026707917 doi "https://doi.org/10.1016/j.aca.2014.08.052" @default.
• W2026707917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25263112" @default.
• W2026707917 hasPublicationYear "2014" @default.
• W2026707917 type Work @default.
• W2026707917 sameAs 2026707917 @default.
• W2026707917 citedByCount "44" @default.
• W2026707917 countsByYear W20267079172015 @default.
• W2026707917 countsByYear W20267079172016 @default.
• W2026707917 countsByYear W20267079172017 @default.
• W2026707917 countsByYear W20267079172018 @default.
• W2026707917 countsByYear W20267079172019 @default.
• W2026707917 countsByYear W20267079172020 @default.
• W2026707917 countsByYear W20267079172021 @default.
• W2026707917 countsByYear W20267079172022 @default.
• W2026707917 countsByYear W20267079172023 @default.
• W2026707917 crossrefType "journal-article" @default.
• W2026707917 hasAuthorship W2026707917A5011547109 @default.
• W2026707917 hasAuthorship W2026707917A5013054784 @default.

• next