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- W2026710337 abstract "Purpose/Objective(s): Pencil-beam (PB) based dose calculation for treatment planning is limited by inaccuracies in regions of tissue inhomogeneities, particularly in situations with lateral electron disequilibrium as is present at tissue/lung interfaces. To overcome these limitations, a new ’’lateral disequilibrium inclusive’’ (LDI) PB based dose calculation algorithm was introduced. In this study we evaluated the accuracy of the new model by film and ionization chamber measurements and Monte Carlo simulations. Materials/Methods: To validate the performance of the new LDI algorithm implemented in Corvus 09, eight test plans were generated on inhomogeneous thorax and pelvis phantoms. In addition, three plans were calculated with a simple effective path length (EPL) algorithm on the inhomogeneous thorax phantom. To simulate homogeneous tissues, four test plans were evaluated in homogeneous phantoms (Homogeneous dose calculation (HOM)). Results:Themeanpixelpassrates andstandarddeviationsofthegamma4%/4mmtestfor thefilmmeasurementswere(96±3)% for the plans calculated with LDI, (70 ± 5)% for the plans calculated with EPL and (99 ± 1)% for the homogeneous plans. Ionization chamber measurements and Monte Carlo simulations confirmed the high accuracy of the new algorithm (dose deviations smaller or equal 4%, gamma 3%/3mm pass rates larger or equal 96%)." @default.
- W2026710337 created "2016-06-24" @default.
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- W2026710337 date "2011-10-01" @default.
- W2026710337 modified "2023-09-27" @default.
- W2026710337 title "Verification Of A Novel Pencil-beam Based Dose Calculation Algorithm With Heterogeneity Correction For Situations Of Lateral Electron Disequilibrium And Comparison With Monte Carlo Calculations" @default.
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- W2026710337 doi "https://doi.org/10.1016/j.ijrobp.2011.06.1621" @default.
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