FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026711247> ?p ?o ?g. }

• W2026711247 endingPage "2136" @default.
• W2026711247 startingPage "2129" @default.
• W2026711247 abstract "A common nonsynonymous single nucleotide polymorphism leading to a serine-to-cysteine substitution at amino acid 704 (Ser704Cys) in the DISC1 protein sequence has been recently associated with schizophrenia and with specific hippocampal abnormalities. Here, we used multimodal neuroimaging to investigate in a large sample of healthy subjects the putative association of the Ser704Cys DISC1 polymorphism with in vivo brain phenotypes including hippocampal formation (HF) gray matter volume and function (as assessed with functional MRI) as well as HF functional coupling with the neural network engaged during encoding of recognition memory. Individuals homozygous for DISC1 Ser allele relative to carriers of the Cys allele showed greater gray matter volume in the HF. Further, Ser/Ser subjects exhibited greater engagement of the HF together with greater HF–dorsolateral prefrontal cortex functional coupling during memory encoding, in spite of similar behavioral performance. These findings consistently support the notion that Ser704Cys DISC1 polymorphism is physiologically relevant. Moreover, they support the hypothesis that genetic variation in DISC1 may affect the risk for schizophrenia by modifying hippocampal gray matter and function." @default.
• W2026711247 created "2016-06-24" @default.
• W2026711247 creator A5004086733 @default.
• W2026711247 creator A5004273244 @default.
• W2026711247 creator A5009215087 @default.
• W2026711247 creator A5010299644 @default.
• W2026711247 creator A5013886328 @default.
• W2026711247 creator A5015541901 @default.
• W2026711247 creator A5024958749 @default.
• W2026711247 creator A5026222709 @default.
• W2026711247 creator A5032859790 @default.
• W2026711247 creator A5035993851 @default.
• W2026711247 creator A5043264677 @default.
• W2026711247 creator A5051045178 @default.
• W2026711247 creator A5074371879 @default.
• W2026711247 creator A5083862490 @default.
• W2026711247 creator A5084026712 @default.
• W2026711247 creator A5084117530 @default.
• W2026711247 date "2008-11-01" @default.
• W2026711247 modified "2023-10-14" @default.
• W2026711247 title "Association of the Ser⁷⁰⁴Cys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding" @default.
• W2026711247 cites W1484497860 @default.
• W2026711247 cites W1779991491 @default.
• W2026711247 cites W1975425704 @default.
• W2026711247 cites W1988193785 @default.
• W2026711247 cites W1994436732 @default.
• W2026711247 cites W1997071197 @default.
• W2026711247 cites W1998022037 @default.
• W2026711247 cites W2002192892 @default.
• W2026711247 cites W2004887039 @default.
• W2026711247 cites W2005790683 @default.
• W2026711247 cites W2009348529 @default.
• W2026711247 cites W2013140323 @default.
• W2026711247 cites W2017720905 @default.
• W2026711247 cites W2025215780 @default.
• W2026711247 cites W2036538226 @default.
• W2026711247 cites W2036790475 @default.
• W2026711247 cites W2040309911 @default.
• W2026711247 cites W2042393535 @default.
• W2026711247 cites W2043915758 @default.
• W2026711247 cites W2044795981 @default.
• W2026711247 cites W2060629467 @default.
• W2026711247 cites W2072406115 @default.
• W2026711247 cites W2076415769 @default.
• W2026711247 cites W2079804240 @default.
• W2026711247 cites W2087680546 @default.
• W2026711247 cites W2089529427 @default.
• W2026711247 cites W2093363441 @default.
• W2026711247 cites W2097578007 @default.
• W2026711247 cites W2103785875 @default.
• W2026711247 cites W2105051672 @default.
• W2026711247 cites W2110402596 @default.
• W2026711247 cites W2118895315 @default.
• W2026711247 cites W2119856466 @default.
• W2026711247 cites W2120708979 @default.
• W2026711247 cites W2127359059 @default.
• W2026711247 cites W2129789527 @default.
• W2026711247 cites W2130417276 @default.
• W2026711247 cites W2132964759 @default.
• W2026711247 cites W2134245236 @default.
• W2026711247 cites W2144351977 @default.
• W2026711247 cites W2144874509 @default.
• W2026711247 cites W2154169426 @default.
• W2026711247 cites W2165517240 @default.
• W2026711247 cites W4230920194 @default.
• W2026711247 doi "https://doi.org/10.1111/j.1460-9568.2008.06482.x" @default.
• W2026711247 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2865560" @default.
• W2026711247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19046394" @default.
• W2026711247 hasPublicationYear "2008" @default.
• W2026711247 type Work @default.
• W2026711247 sameAs 2026711247 @default.
• W2026711247 citedByCount "86" @default.
• W2026711247 countsByYear W20267112472012 @default.
• W2026711247 countsByYear W20267112472013 @default.
• W2026711247 countsByYear W20267112472014 @default.
• W2026711247 countsByYear W20267112472015 @default.
• W2026711247 countsByYear W20267112472016 @default.
• W2026711247 countsByYear W20267112472017 @default.
• W2026711247 countsByYear W20267112472018 @default.
• W2026711247 countsByYear W20267112472020 @default.
• W2026711247 countsByYear W20267112472022 @default.
• W2026711247 countsByYear W20267112472023 @default.
• W2026711247 crossrefType "journal-article" @default.
• W2026711247 hasAuthorship W2026711247A5004086733 @default.
• W2026711247 hasAuthorship W2026711247A5004273244 @default.
• W2026711247 hasAuthorship W2026711247A5009215087 @default.
• W2026711247 hasAuthorship W2026711247A5010299644 @default.
• W2026711247 hasAuthorship W2026711247A5013886328 @default.
• W2026711247 hasAuthorship W2026711247A5015541901 @default.
• W2026711247 hasAuthorship W2026711247A5024958749 @default.
• W2026711247 hasAuthorship W2026711247A5026222709 @default.
• W2026711247 hasAuthorship W2026711247A5032859790 @default.
• W2026711247 hasAuthorship W2026711247A5035993851 @default.
• W2026711247 hasAuthorship W2026711247A5043264677 @default.
• W2026711247 hasAuthorship W2026711247A5051045178 @default.
• W2026711247 hasAuthorship W2026711247A5074371879 @default.
• W2026711247 hasAuthorship W2026711247A5083862490 @default.
• W2026711247 hasAuthorship W2026711247A5084026712 @default.

• next