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- W2026712711 abstract "The study by Sheth et al. examines the citation rates for published studies comparing internal fixation with arthroplasty for the treatment of hip fractures, and the authors report an overall citation rate of only 56% even when a five-year lag in publication is granted. More importantly, Sheth et al. provide the results of a cumulative meta-analysis of twelve studies revealing “a stable estimate of at least a 60% reduction in risk of revision with arthroplasty” present after the fifth study, performed in the year 2000. On the basis of the provided information, at least one, and possibly more, of the trials began enrolling patients after the year 2000. As a result, the authors ultimately question “the continued exposure of patients to interventions that have proved to be less effective,” calling into question the timing of the existence of clinical equipoise in the treatment of hip fractures.The foundation of all research rests in the clinical question, which serves as the first and most important step in the design of a potential trial. Once a question is posed, the next logical step involves a thorough review of the existing literature to …" @default.
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- W2026712711 date "2011-11-16" @default.
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- W2026712711 title "When Does Clinical Equipoise Cease to Exist?" @default.
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- W2026712711 doi "https://doi.org/10.2106/jbjs.k.01157" @default.
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