FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026763399> ?p ?o ?g. }

• W2026763399 endingPage "181" @default.
• W2026763399 startingPage "171" @default.
• W2026763399 abstract "The thermal stability of acid-soluble collagen type I from calf skin in salt solutions is studied by high-sensitivity differential scanning calorimetry. Three concentration ranges have been clearly distinguished in the dependence of collagen thermal stability on ion concentration. At concentrations below 20 mM, all studied salts reduce the temperature of collagen denaturation with a factor of about 0.2 degree C per 1 mM. This effect is attributed to screening of electrostatic interactions leading to collagen stabilisation. At higher concentrations, roughly in the range 20-500 mM, the different salts either slightly stabilise or further destabilise the collagen molecule in salt-specific way that correlates with their position in the lyotropic series. The effect of anions is dominating and follows the order H2PO4- > or = SO4(2-) > Cl- > SCN-, with sign inversion at about SO4(2-). This effect, generally known as the Hofmeister effect, is associated with indirect protein-salt interactions exerted via competition for water molecules between ions and the protein surface. At still higher salt concentrations (onset concentrations between 200 and 800 mM for the different salts), the temperature of collagen denaturation and solution opacity markedly increase for all studied salts due to protein salting out and aggregation. The ability of salts to salt out collagen also correlates with their position in the lyotropic series and increases for chaotropic ions. The SO4(2-) anions interact specifically with collagen - they induce splitting of the protein denaturation peak into two components in the range 100-150 mM Na2SO4 and 300-750 mM Li2SO4. The variations of the collagen denaturation enthalpy at low and intermediate salt concentrations are consistent with a weak linear increase of the enthalpy with denaturation temperature. Its derivative, d(delta H)/dT, is approximately equal to the independently measured difference in the heat capacities of the denatured and native states, delta Cp = Cp(D) - Cp(N) approximately 0.1 cal.g-1 K-1." @default.
• W2026763399 created "2016-06-24" @default.
• W2026763399 creator A5022182739 @default.
• W2026763399 creator A5039249456 @default.
• W2026763399 creator A5074169677 @default.
• W2026763399 creator A5083265925 @default.
• W2026763399 date "1996-10-01" @default.
• W2026763399 modified "2023-10-14" @default.
• W2026763399 title "Thermal stability of calf skin collagen type I in salt solutions" @default.
• W2026763399 cites W1502562311 @default.
• W2026763399 cites W1548126479 @default.
• W2026763399 cites W1564482854 @default.
• W2026763399 cites W1565263903 @default.
• W2026763399 cites W1589112374 @default.
• W2026763399 cites W1832142381 @default.
• W2026763399 cites W1936370692 @default.
• W2026763399 cites W1964196511 @default.
• W2026763399 cites W1971613252 @default.
• W2026763399 cites W1972989128 @default.
• W2026763399 cites W1974088267 @default.
• W2026763399 cites W1978987630 @default.
• W2026763399 cites W1979221090 @default.
• W2026763399 cites W1984210861 @default.
• W2026763399 cites W2006693760 @default.
• W2026763399 cites W2009067534 @default.
• W2026763399 cites W2016632758 @default.
• W2026763399 cites W2034220147 @default.
• W2026763399 cites W2035066110 @default.
• W2026763399 cites W2045536741 @default.
• W2026763399 cites W2046320938 @default.
• W2026763399 cites W2048503608 @default.
• W2026763399 cites W2051674637 @default.
• W2026763399 cites W2053619086 @default.
• W2026763399 cites W2055118741 @default.
• W2026763399 cites W2055826477 @default.
• W2026763399 cites W2072545366 @default.
• W2026763399 cites W2077941741 @default.
• W2026763399 cites W2082402523 @default.
• W2026763399 cites W2084961147 @default.
• W2026763399 cites W2089715297 @default.
• W2026763399 cites W2091126137 @default.
• W2026763399 cites W2097707959 @default.
• W2026763399 cites W2135964386 @default.
• W2026763399 cites W2145165079 @default.
• W2026763399 cites W2422195796 @default.
• W2026763399 cites W4300941906 @default.
• W2026763399 cites W4317640641 @default.
• W2026763399 cites W998400604 @default.
• W2026763399 doi "https://doi.org/10.1016/s0167-4838(96)00092-1" @default.
• W2026763399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8917619" @default.
• W2026763399 hasPublicationYear "1996" @default.
• W2026763399 type Work @default.
• W2026763399 sameAs 2026763399 @default.
• W2026763399 citedByCount "107" @default.
• W2026763399 countsByYear W20267633992012 @default.
• W2026763399 countsByYear W20267633992013 @default.
• W2026763399 countsByYear W20267633992014 @default.
• W2026763399 countsByYear W20267633992015 @default.
• W2026763399 countsByYear W20267633992016 @default.
• W2026763399 countsByYear W20267633992017 @default.
• W2026763399 countsByYear W20267633992018 @default.
• W2026763399 countsByYear W20267633992019 @default.
• W2026763399 countsByYear W20267633992020 @default.
• W2026763399 countsByYear W20267633992021 @default.
• W2026763399 countsByYear W20267633992022 @default.
• W2026763399 countsByYear W20267633992023 @default.
• W2026763399 crossrefType "journal-article" @default.
• W2026763399 hasAuthorship W2026763399A5022182739 @default.
• W2026763399 hasAuthorship W2026763399A5039249456 @default.
• W2026763399 hasAuthorship W2026763399A5074169677 @default.
• W2026763399 hasAuthorship W2026763399A5083265925 @default.
• W2026763399 hasConcept C102362939 @default.
• W2026763399 hasConcept C121332964 @default.
• W2026763399 hasConcept C13965031 @default.
• W2026763399 hasConcept C145148216 @default.
• W2026763399 hasConcept C148280534 @default.
• W2026763399 hasConcept C178790620 @default.
• W2026763399 hasConcept C185592680 @default.
• W2026763399 hasConcept C2776371256 @default.
• W2026763399 hasConcept C2776923230 @default.
• W2026763399 hasConcept C2994273327 @default.
• W2026763399 hasConcept C39519442 @default.
• W2026763399 hasConcept C43617362 @default.
• W2026763399 hasConcept C521977710 @default.
• W2026763399 hasConcept C58436429 @default.
• W2026763399 hasConcept C59061564 @default.
• W2026763399 hasConcept C97355855 @default.
• W2026763399 hasConceptScore W2026763399C102362939 @default.
• W2026763399 hasConceptScore W2026763399C121332964 @default.
• W2026763399 hasConceptScore W2026763399C13965031 @default.
• W2026763399 hasConceptScore W2026763399C145148216 @default.
• W2026763399 hasConceptScore W2026763399C148280534 @default.
• W2026763399 hasConceptScore W2026763399C178790620 @default.
• W2026763399 hasConceptScore W2026763399C185592680 @default.
• W2026763399 hasConceptScore W2026763399C2776371256 @default.
• W2026763399 hasConceptScore W2026763399C2776923230 @default.
• W2026763399 hasConceptScore W2026763399C2994273327 @default.
• W2026763399 hasConceptScore W2026763399C39519442 @default.

• next