FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026808212> ?p ?o ?g. }

• W2026808212 endingPage "3173" @default.
• W2026808212 startingPage "3166" @default.
• W2026808212 abstract "The fruit of Docynia delavayi (Franch.) Schneid is a kind of popular food in southwestern areas of China. Additionally, its rhizome has been long used as a folk medicine in the treatment of liver cancer by local people. Chrysin is a kind of flavonoid which induces cancer cell death in vitro. However, its anti-tumor activity in vivo and toxicological effects on the tumor-bearing animals still remain poorly understood. In this study, we obtained four flavonoids from this herb. Among them, chrysin showed the strongest cytotoxic effect on an array of cultured tumor cells. Further investigations revealed that it significantly repressed transplanted H22 ascitic hepatic tumor cell growth in vivo. Moreover, this compound displayed little toxic effects. Additionally, we demonstrated that in transplanted tumor tissues, chrysin not only activated caspase-3 and induced apoptosis, but also inhibited the production of vascular endothelial growth factor (VEGF) and suppressed angiogenesis. These data showed that chrysin exhibited prominent anti-tumor activities and low toxic effects in vivo." @default.
• W2026808212 created "2016-06-24" @default.
• W2026808212 creator A5005435547 @default.
• W2026808212 creator A5006093334 @default.
• W2026808212 creator A5024980582 @default.
• W2026808212 creator A5025876382 @default.
• W2026808212 creator A5038633996 @default.
• W2026808212 creator A5079486417 @default.
• W2026808212 date "2012-09-01" @default.
• W2026808212 modified "2023-10-15" @default.
• W2026808212 title "A flavonoid component from Docynia delavayi (Franch.) Schneid represses transplanted H22 hepatoma growth and exhibits low toxic effect on tumor-bearing mice" @default.
• W2026808212 cites W1515344935 @default.
• W2026808212 cites W1967342027 @default.
• W2026808212 cites W1971173618 @default.
• W2026808212 cites W1979585278 @default.
• W2026808212 cites W2006431138 @default.
• W2026808212 cites W2017088472 @default.
• W2026808212 cites W2020351001 @default.
• W2026808212 cites W2025561722 @default.
• W2026808212 cites W2069651416 @default.
• W2026808212 cites W2070144912 @default.
• W2026808212 cites W2072093120 @default.
• W2026808212 cites W2087326187 @default.
• W2026808212 cites W2090803856 @default.
• W2026808212 cites W2090994090 @default.
• W2026808212 cites W2094040857 @default.
• W2026808212 cites W2095279903 @default.
• W2026808212 cites W2104300873 @default.
• W2026808212 cites W2117525179 @default.
• W2026808212 cites W2154758903 @default.
• W2026808212 cites W2158504441 @default.
• W2026808212 cites W1998514664 @default.
• W2026808212 doi "https://doi.org/10.1016/j.fct.2012.05.039" @default.
• W2026808212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22687553" @default.
• W2026808212 hasPublicationYear "2012" @default.
• W2026808212 type Work @default.
• W2026808212 sameAs 2026808212 @default.
• W2026808212 citedByCount "34" @default.
• W2026808212 countsByYear W20268082122013 @default.
• W2026808212 countsByYear W20268082122014 @default.
• W2026808212 countsByYear W20268082122015 @default.
• W2026808212 countsByYear W20268082122016 @default.
• W2026808212 countsByYear W20268082122017 @default.
• W2026808212 countsByYear W20268082122018 @default.
• W2026808212 countsByYear W20268082122020 @default.
• W2026808212 countsByYear W20268082122021 @default.
• W2026808212 countsByYear W20268082122022 @default.
• W2026808212 countsByYear W20268082122023 @default.
• W2026808212 crossrefType "journal-article" @default.
• W2026808212 hasAuthorship W2026808212A5005435547 @default.
• W2026808212 hasAuthorship W2026808212A5006093334 @default.
• W2026808212 hasAuthorship W2026808212A5024980582 @default.
• W2026808212 hasAuthorship W2026808212A5025876382 @default.
• W2026808212 hasAuthorship W2026808212A5038633996 @default.
• W2026808212 hasAuthorship W2026808212A5079486417 @default.
• W2026808212 hasConcept C150903083 @default.
• W2026808212 hasConcept C154317977 @default.
• W2026808212 hasConcept C185592680 @default.
• W2026808212 hasConcept C190283241 @default.
• W2026808212 hasConcept C202751555 @default.
• W2026808212 hasConcept C207001950 @default.
• W2026808212 hasConcept C2778004101 @default.
• W2026808212 hasConcept C2779054382 @default.
• W2026808212 hasConcept C2779478871 @default.
• W2026808212 hasConcept C2780394083 @default.
• W2026808212 hasConcept C502942594 @default.
• W2026808212 hasConcept C55493867 @default.
• W2026808212 hasConcept C86803240 @default.
• W2026808212 hasConcept C98274493 @default.
• W2026808212 hasConceptScore W2026808212C150903083 @default.
• W2026808212 hasConceptScore W2026808212C154317977 @default.
• W2026808212 hasConceptScore W2026808212C185592680 @default.
• W2026808212 hasConceptScore W2026808212C190283241 @default.
• W2026808212 hasConceptScore W2026808212C202751555 @default.
• W2026808212 hasConceptScore W2026808212C207001950 @default.
• W2026808212 hasConceptScore W2026808212C2778004101 @default.
• W2026808212 hasConceptScore W2026808212C2779054382 @default.
• W2026808212 hasConceptScore W2026808212C2779478871 @default.
• W2026808212 hasConceptScore W2026808212C2780394083 @default.
• W2026808212 hasConceptScore W2026808212C502942594 @default.
• W2026808212 hasConceptScore W2026808212C55493867 @default.
• W2026808212 hasConceptScore W2026808212C86803240 @default.
• W2026808212 hasConceptScore W2026808212C98274493 @default.
• W2026808212 hasFunder F4320321001 @default.
• W2026808212 hasIssue "9" @default.
• W2026808212 hasLocation W20268082121 @default.
• W2026808212 hasLocation W20268082122 @default.
• W2026808212 hasOpenAccess W2026808212 @default.
• W2026808212 hasPrimaryLocation W20268082121 @default.
• W2026808212 hasRelatedWork W2050306700 @default.
• W2026808212 hasRelatedWork W2109994537 @default.
• W2026808212 hasRelatedWork W2368257851 @default.
• W2026808212 hasRelatedWork W2382426014 @default.
• W2026808212 hasRelatedWork W2385215236 @default.
• W2026808212 hasRelatedWork W2391929210 @default.
• W2026808212 hasRelatedWork W2399802050 @default.
• W2026808212 hasRelatedWork W2433311123 @default.
• W2026808212 hasRelatedWork W3094020906 @default.

• next