FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026859306> ?p ?o ?g. }

• W2026859306 endingPage "559" @default.
• W2026859306 startingPage "553" @default.
• W2026859306 abstract "The aim of the current study was to examine the influence of interaction between polymorphisms of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C with angiotensin converting enzyme insertion/deletion (ACE I/D) polymorphism on the risk of diabetic nephropathy (DN). In a case control study using polymerase chain reaction (PCR)- and PCR-restriction fragment length polymorphism (RFLP), the presence of three polymorphisms in 140 patients with type 2 diabetes mellitus (T2DM) with nephropathy including patients with micro- and macro-albuminuria and 72 patients with normoalbuminuria from Western Iran were investigated. In the presence of both MTHFR 677 T and ACE D alleles, there was a trend toward increased risk of DN 2.68-fold (p=0.054). The possession of both MTHFR 677 T and ACE D alleles increased the risk of macro-albuminuria four times (p=0.035). The concomitant presence of both MTHFR 1298 C and ACE D alleles increased the risk of macro-albuminuria 7.8-fold (p=0.012). In addition, the risk of progression from micro- to macro-albuminuria in the presence of both alleles tended to be increased (4.1-fold, p=0.09). Our study for the first time demonstrated a synergistic effect between ACE I/D with either MTHFR C677T or A1298C polymorphism on the increased risk of DN among patients with T2DM. We found that MTHFR 1298 C strongly interacts with the ACE D allele and augments the risk of DN in our population." @default.
• W2026859306 created "2016-06-24" @default.
• W2026859306 creator A5028853982 @default.
• W2026859306 creator A5073599869 @default.
• W2026859306 creator A5088838431 @default.
• W2026859306 date "2012-04-01" @default.
• W2026859306 modified "2023-10-14" @default.
• W2026859306 title "Interaction of<i>MTHFR</i>1298C with<i>ACE</i>D Allele Augments the Risk of Diabetic Nephropathy in Western Iran" @default.
• W2026859306 cites W1965430426 @default.
• W2026859306 cites W1965596192 @default.
• W2026859306 cites W1981923492 @default.
• W2026859306 cites W1984024405 @default.
• W2026859306 cites W1984236905 @default.
• W2026859306 cites W1986848060 @default.
• W2026859306 cites W1988342347 @default.
• W2026859306 cites W1991602875 @default.
• W2026859306 cites W2007937775 @default.
• W2026859306 cites W2008205161 @default.
• W2026859306 cites W2012472140 @default.
• W2026859306 cites W2018105279 @default.
• W2026859306 cites W2021854531 @default.
• W2026859306 cites W2025279756 @default.
• W2026859306 cites W2045706069 @default.
• W2026859306 cites W2047085768 @default.
• W2026859306 cites W2049489625 @default.
• W2026859306 cites W2049530448 @default.
• W2026859306 cites W2055966273 @default.
• W2026859306 cites W2057708963 @default.
• W2026859306 cites W2063232491 @default.
• W2026859306 cites W2087388742 @default.
• W2026859306 cites W2090746956 @default.
• W2026859306 cites W2102506041 @default.
• W2026859306 cites W2107310851 @default.
• W2026859306 cites W2112839082 @default.
• W2026859306 cites W2113130878 @default.
• W2026859306 cites W2113362652 @default.
• W2026859306 cites W2114922552 @default.
• W2026859306 cites W2122816593 @default.
• W2026859306 cites W2125484955 @default.
• W2026859306 cites W2141178151 @default.
• W2026859306 cites W2165715420 @default.
• W2026859306 cites W2416046640 @default.
• W2026859306 doi "https://doi.org/10.1089/dna.2011.1364" @default.
• W2026859306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21942443" @default.
• W2026859306 hasPublicationYear "2012" @default.
• W2026859306 type Work @default.
• W2026859306 sameAs 2026859306 @default.
• W2026859306 citedByCount "19" @default.
• W2026859306 countsByYear W20268593062012 @default.
• W2026859306 countsByYear W20268593062013 @default.
• W2026859306 countsByYear W20268593062014 @default.
• W2026859306 countsByYear W20268593062015 @default.
• W2026859306 countsByYear W20268593062016 @default.
• W2026859306 countsByYear W20268593062017 @default.
• W2026859306 countsByYear W20268593062019 @default.
• W2026859306 countsByYear W20268593062020 @default.
• W2026859306 countsByYear W20268593062021 @default.
• W2026859306 countsByYear W20268593062023 @default.
• W2026859306 crossrefType "journal-article" @default.
• W2026859306 hasAuthorship W2026859306A5028853982 @default.
• W2026859306 hasAuthorship W2026859306A5073599869 @default.
• W2026859306 hasAuthorship W2026859306A5088838431 @default.
• W2026859306 hasConcept C104317684 @default.
• W2026859306 hasConcept C126322002 @default.
• W2026859306 hasConcept C134018914 @default.
• W2026859306 hasConcept C135763542 @default.
• W2026859306 hasConcept C168007829 @default.
• W2026859306 hasConcept C180754005 @default.
• W2026859306 hasConcept C27016395 @default.
• W2026859306 hasConcept C2776174234 @default.
• W2026859306 hasConcept C2779922275 @default.
• W2026859306 hasConcept C2781184683 @default.
• W2026859306 hasConcept C2908647359 @default.
• W2026859306 hasConcept C43563269 @default.
• W2026859306 hasConcept C54355233 @default.
• W2026859306 hasConcept C555293320 @default.
• W2026859306 hasConcept C71924100 @default.
• W2026859306 hasConcept C84393581 @default.
• W2026859306 hasConcept C86803240 @default.
• W2026859306 hasConcept C99454951 @default.
• W2026859306 hasConceptScore W2026859306C104317684 @default.
• W2026859306 hasConceptScore W2026859306C126322002 @default.
• W2026859306 hasConceptScore W2026859306C134018914 @default.
• W2026859306 hasConceptScore W2026859306C135763542 @default.
• W2026859306 hasConceptScore W2026859306C168007829 @default.
• W2026859306 hasConceptScore W2026859306C180754005 @default.
• W2026859306 hasConceptScore W2026859306C27016395 @default.
• W2026859306 hasConceptScore W2026859306C2776174234 @default.
• W2026859306 hasConceptScore W2026859306C2779922275 @default.
• W2026859306 hasConceptScore W2026859306C2781184683 @default.
• W2026859306 hasConceptScore W2026859306C2908647359 @default.
• W2026859306 hasConceptScore W2026859306C43563269 @default.
• W2026859306 hasConceptScore W2026859306C54355233 @default.
• W2026859306 hasConceptScore W2026859306C555293320 @default.
• W2026859306 hasConceptScore W2026859306C71924100 @default.
• W2026859306 hasConceptScore W2026859306C84393581 @default.
• W2026859306 hasConceptScore W2026859306C86803240 @default.
• W2026859306 hasConceptScore W2026859306C99454951 @default.

• next