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- W2026870530 abstract "A convenient route to N-substituted bis-C-alkylamidines possessing antiplasmodial activity and their oxadiazolone and amidoxime prodrug candidates, is described. These three families of compounds were available after a key N-alkylation step of the parent oxadiazolone 1a. Testing of the three compound classes in vitro and in vivo is also presented." @default.
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- W2026870530 date "2009-09-01" @default.
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- W2026870530 title "N-substituted bis-C-alkyloxadiazolones as dual effectors: Efficient intermediates to amidoximes or amidines and prodrug candidates of potent antimalarials" @default.
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- W2026870530 doi "https://doi.org/10.1016/j.bmcl.2009.07.001" @default.
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