FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026902237> ?p ?o ?g. }

• W2026902237 endingPage "623" @default.
• W2026902237 startingPage "617" @default.
• W2026902237 abstract "Recent studies have shown that endothelin-1 (ET-1) antagonists increase sodium excretion and improve renal blood flow in experimental heart failure (HF). However, despite a number of investigations that have reported a significant increase in ET-1 plasma levels in patients with HF, it is still not known whether increased renal synthesis and urinary excretion of ET-1 occur. Our aim was to investigate renal ET-1 formation and its relation to sodium excretion in patients with HF.One hundred forty-seven patients with HF, subdivided according to New York Heart Association (NYHA) functional classes, and 28 healthy controls were studied. ET-1 and big ET-1 were measured in plasma and in 24-hour urine by radioimmunoassay. Atrial and brain natriuretic peptide, arginine vasopressin, plasma renin activity, and hemodynamic variables were also investigated.Urinary ET-1 excretion was already increased in NYHA class II patients (P <.001 vs controls), whereas plasma ET-1 increased only in NYHA class III and IV patients (P <.001). In the 71 subjects who were not receiving diuretic treatment, urinary ET-1 was selected as the strongest predictor of sodium excretion by multivariate stepwise analysis.Urinary ET-1 excretion increases in an earlier phase of HF than plasma ET-1 and appears to be closely correlated with sodium excretion, indicating renal ET-1 is a target for ET-1 antagonists in patients with HF." @default.
• W2026902237 created "2016-06-24" @default.
• W2026902237 creator A5021156354 @default.
• W2026902237 creator A5045059633 @default.
• W2026902237 creator A5050057021 @default.
• W2026902237 creator A5054696472 @default.
• W2026902237 creator A5063277464 @default.
• W2026902237 creator A5071389528 @default.
• W2026902237 date "2000-10-01" @default.
• W2026902237 modified "2023-10-15" @default.
• W2026902237 title "Renal endothelin in heart failure and its relation to sodium excretion" @default.
• W2026902237 cites W1813207029 @default.
• W2026902237 cites W1968309000 @default.
• W2026902237 cites W1979460197 @default.
• W2026902237 cites W1990332210 @default.
• W2026902237 cites W1993972994 @default.
• W2026902237 cites W1997524181 @default.
• W2026902237 cites W2040441956 @default.
• W2026902237 cites W2040703850 @default.
• W2026902237 cites W2042526294 @default.
• W2026902237 cites W2075075037 @default.
• W2026902237 cites W2076644187 @default.
• W2026902237 cites W2085596429 @default.
• W2026902237 cites W2120931745 @default.
• W2026902237 cites W2126047256 @default.
• W2026902237 cites W2129330037 @default.
• W2026902237 cites W2141316079 @default.
• W2026902237 cites W2151571701 @default.
• W2026902237 cites W2156481396 @default.
• W2026902237 cites W2170598368 @default.
• W2026902237 cites W2183527167 @default.
• W2026902237 cites W2395791968 @default.
• W2026902237 cites W2402269490 @default.
• W2026902237 cites W2416016109 @default.
• W2026902237 doi "https://doi.org/10.1067/mhj.2000.109917" @default.
• W2026902237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11011335" @default.
• W2026902237 hasPublicationYear "2000" @default.
• W2026902237 type Work @default.
• W2026902237 sameAs 2026902237 @default.
• W2026902237 citedByCount "23" @default.
• W2026902237 countsByYear W20269022372012 @default.
• W2026902237 countsByYear W20269022372013 @default.
• W2026902237 countsByYear W20269022372015 @default.
• W2026902237 countsByYear W20269022372023 @default.
• W2026902237 crossrefType "journal-article" @default.
• W2026902237 hasAuthorship W2026902237A5021156354 @default.
• W2026902237 hasAuthorship W2026902237A5045059633 @default.
• W2026902237 hasAuthorship W2026902237A5050057021 @default.
• W2026902237 hasAuthorship W2026902237A5054696472 @default.
• W2026902237 hasAuthorship W2026902237A5063277464 @default.
• W2026902237 hasAuthorship W2026902237A5071389528 @default.
• W2026902237 hasBestOaLocation W20269022372 @default.
• W2026902237 hasConcept C10146269 @default.
• W2026902237 hasConcept C126322002 @default.
• W2026902237 hasConcept C134018914 @default.
• W2026902237 hasConcept C138976137 @default.
• W2026902237 hasConcept C144980905 @default.
• W2026902237 hasConcept C161457703 @default.
• W2026902237 hasConcept C170493617 @default.
• W2026902237 hasConcept C198710026 @default.
• W2026902237 hasConcept C2776370428 @default.
• W2026902237 hasConcept C2778069365 @default.
• W2026902237 hasConcept C2778198053 @default.
• W2026902237 hasConcept C2779918671 @default.
• W2026902237 hasConcept C2780018836 @default.
• W2026902237 hasConcept C2780091579 @default.
• W2026902237 hasConcept C71924100 @default.
• W2026902237 hasConcept C77411442 @default.
• W2026902237 hasConcept C84393581 @default.
• W2026902237 hasConceptScore W2026902237C10146269 @default.
• W2026902237 hasConceptScore W2026902237C126322002 @default.
• W2026902237 hasConceptScore W2026902237C134018914 @default.
• W2026902237 hasConceptScore W2026902237C138976137 @default.
• W2026902237 hasConceptScore W2026902237C144980905 @default.
• W2026902237 hasConceptScore W2026902237C161457703 @default.
• W2026902237 hasConceptScore W2026902237C170493617 @default.
• W2026902237 hasConceptScore W2026902237C198710026 @default.
• W2026902237 hasConceptScore W2026902237C2776370428 @default.
• W2026902237 hasConceptScore W2026902237C2778069365 @default.
• W2026902237 hasConceptScore W2026902237C2778198053 @default.
• W2026902237 hasConceptScore W2026902237C2779918671 @default.
• W2026902237 hasConceptScore W2026902237C2780018836 @default.
• W2026902237 hasConceptScore W2026902237C2780091579 @default.
• W2026902237 hasConceptScore W2026902237C71924100 @default.
• W2026902237 hasConceptScore W2026902237C77411442 @default.
• W2026902237 hasConceptScore W2026902237C84393581 @default.
• W2026902237 hasIssue "4" @default.
• W2026902237 hasLocation W20269022371 @default.
• W2026902237 hasLocation W20269022372 @default.
• W2026902237 hasLocation W20269022373 @default.
• W2026902237 hasOpenAccess W2026902237 @default.
• W2026902237 hasPrimaryLocation W20269022371 @default.
• W2026902237 hasRelatedWork W2022440729 @default.
• W2026902237 hasRelatedWork W2035497047 @default.
• W2026902237 hasRelatedWork W2054676168 @default.
• W2026902237 hasRelatedWork W2222787040 @default.
• W2026902237 hasRelatedWork W2300081670 @default.
• W2026902237 hasRelatedWork W2313058495 @default.

• next