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- W2026943640 abstract "The study assessed possible age differences in brain activation patterns to low dose ethanol (.5 g/kg intraperitoneally) and the influence of social context on this activation. Early adolescent or young adult male Sprague-Dawley rats were placed either alone or with an unfamiliar partner of the same age and sex following saline or ethanol administration. c-Fos protein immunoreactivity was used to index neuronal activation in 15 regions of interest. Ethanol had little effect on c-Fos activation. In adolescents, social context activated an autonomic network including the basolateral and central amygdala, bed nucleus of the stria terminalis, lateral hypothalamus, and lateral septum. In contrast, when adult rats were alone, activation was evident in a reward network that included the substantia nigra, nucleus accumbens, anterior cingulate and orbitofrontal cortices, lateral parabrachial nucleus, and locus coeruleus." @default.
- W2026943640 created "2016-06-24" @default.
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- W2026943640 date "2012-01-01" @default.
- W2026943640 modified "2023-10-16" @default.
- W2026943640 title "Social context induces two unique patterns of c-Fos expression in adolescent and adult rats" @default.
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- W2026943640 doi "https://doi.org/10.1002/dev.21064" @default.
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