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- W2026961330 abstract "Isolated chromaffin granules aggregate reversibly in the presence of Ca2+ and Mg2+. The adhering membranes maximise their areas of contact, leading to distortions of the granules and, in many cases, to membrane rupture. The adhesion is accompanied by changes in the structure of the core: it is seen to withdraw from regions of the membrane that are involved in adhesion to other granules, although it remains in contact with the membrane at other places. At the same time the osmotic pressure within the granules increases and their soluble components are released to the medium. These processes can occur at 0 °C, and at low pH, as well as at room temperature and pH 7. Similar reorganisation of membranes and cores may occur during the process of Ca2+-dependent exocytosis in secretion." @default.
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- W2026961330 date "1974-07-01" @default.
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- W2026961330 title "Structural changes in chromaffin granules induced by divalent cations" @default.
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- W2026961330 doi "https://doi.org/10.1016/0005-2736(74)90280-6" @default.
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