FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026966628> ?p ?o ?g. }

• W2026966628 endingPage "47" @default.
• W2026966628 startingPage "42" @default.
• W2026966628 abstract "Neuroblastoma is a tumor of infancy that presents several chromosomal abnormalities. Nonrandom deletion of chromosome arm 9p has been identified in primary neuroblastoma suggesting the presence of a tumor suppressor gene located on this chromosome. In previous work, we showed that CDKN2A and CDKN2B genes, mapped at 9p21, were not deleted in neuroblastoma cells. In the present article, we refine the deleted region of 9p using polymerase chain reaction-based analysis of highly polymorphic simple sequence repeats and a two color fluorescence in situ hybridization technique on interphase nuclei. We analyzed 71 primary tumors of patients at the onset of the disease. We found loss of heterozygosity (LOH) in 16 of 71 (23%) cases; the frequency of LOH for 9p was higher (28%) in favorable stages 1, 2, and 4s than in unfavorable stages 3 and 4 (14%). Our results identify two regions of frequent allelic loss: the first at the locus D9S1849 and the second at the locus D9S157. These regions appear to be distant from CDKN2A and CDKN2B loci suggesting that other genes may be involved in 9p deletion. Finally, our data show that 9p deletion is more frequent in tumors of patients with a favorable prognosis, indicating that deleted genes may not be crucial for tumor progression." @default.
• W2026966628 created "2016-06-24" @default.
• W2026966628 creator A5001470699 @default.
• W2026966628 creator A5022755764 @default.
• W2026966628 creator A5032601645 @default.
• W2026966628 creator A5044285201 @default.
• W2026966628 creator A5047048269 @default.
• W2026966628 creator A5053578539 @default.
• W2026966628 date "2002-05-01" @default.
• W2026966628 modified "2023-10-17" @default.
• W2026966628 title "Two regions of deletion in 9p22∼p24 in neuroblastoma are frequently observed in favorable tumors" @default.
• W2026966628 cites W1502880561 @default.
• W2026966628 cites W1967629683 @default.
• W2026966628 cites W1982838213 @default.
• W2026966628 cites W2001258296 @default.
• W2026966628 cites W2001937439 @default.
• W2026966628 cites W2020171884 @default.
• W2026966628 cites W2022329296 @default.
• W2026966628 cites W2033298419 @default.
• W2026966628 cites W2036296056 @default.
• W2026966628 cites W2040535584 @default.
• W2026966628 cites W2056738023 @default.
• W2026966628 cites W2058205104 @default.
• W2026966628 cites W2066389392 @default.
• W2026966628 cites W2083566287 @default.
• W2026966628 cites W2094253953 @default.
• W2026966628 cites W2096398040 @default.
• W2026966628 cites W2127012800 @default.
• W2026966628 cites W2130002311 @default.
• W2026966628 cites W2326051492 @default.
• W2026966628 doi "https://doi.org/10.1016/s0165-4608(01)00640-9" @default.
• W2026966628 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12072202" @default.
• W2026966628 hasPublicationYear "2002" @default.
• W2026966628 type Work @default.
• W2026966628 sameAs 2026966628 @default.
• W2026966628 citedByCount "20" @default.
• W2026966628 countsByYear W20269666282012 @default.
• W2026966628 countsByYear W20269666282013 @default.
• W2026966628 countsByYear W20269666282015 @default.
• W2026966628 countsByYear W20269666282016 @default.
• W2026966628 countsByYear W20269666282018 @default.
• W2026966628 countsByYear W20269666282019 @default.
• W2026966628 countsByYear W20269666282022 @default.
• W2026966628 crossrefType "journal-article" @default.
• W2026966628 hasAuthorship W2026966628A5001470699 @default.
• W2026966628 hasAuthorship W2026966628A5022755764 @default.
• W2026966628 hasAuthorship W2026966628A5032601645 @default.
• W2026966628 hasAuthorship W2026966628A5044285201 @default.
• W2026966628 hasAuthorship W2026966628A5047048269 @default.
• W2026966628 hasAuthorship W2026966628A5053578539 @default.
• W2026966628 hasConcept C104317684 @default.
• W2026966628 hasConcept C143589142 @default.
• W2026966628 hasConcept C153911025 @default.
• W2026966628 hasConcept C180754005 @default.
• W2026966628 hasConcept C2776300330 @default.
• W2026966628 hasConcept C2776715637 @default.
• W2026966628 hasConcept C2777542201 @default.
• W2026966628 hasConcept C2778264664 @default.
• W2026966628 hasConcept C2780265364 @default.
• W2026966628 hasConcept C30481170 @default.
• W2026966628 hasConcept C502942594 @default.
• W2026966628 hasConcept C54355233 @default.
• W2026966628 hasConcept C555283112 @default.
• W2026966628 hasConcept C81885089 @default.
• W2026966628 hasConcept C84597430 @default.
• W2026966628 hasConcept C86803240 @default.
• W2026966628 hasConceptScore W2026966628C104317684 @default.
• W2026966628 hasConceptScore W2026966628C143589142 @default.
• W2026966628 hasConceptScore W2026966628C153911025 @default.
• W2026966628 hasConceptScore W2026966628C180754005 @default.
• W2026966628 hasConceptScore W2026966628C2776300330 @default.
• W2026966628 hasConceptScore W2026966628C2776715637 @default.
• W2026966628 hasConceptScore W2026966628C2777542201 @default.
• W2026966628 hasConceptScore W2026966628C2778264664 @default.
• W2026966628 hasConceptScore W2026966628C2780265364 @default.
• W2026966628 hasConceptScore W2026966628C30481170 @default.
• W2026966628 hasConceptScore W2026966628C502942594 @default.
• W2026966628 hasConceptScore W2026966628C54355233 @default.
• W2026966628 hasConceptScore W2026966628C555283112 @default.
• W2026966628 hasConceptScore W2026966628C81885089 @default.
• W2026966628 hasConceptScore W2026966628C84597430 @default.
• W2026966628 hasConceptScore W2026966628C86803240 @default.
• W2026966628 hasIssue "1" @default.
• W2026966628 hasLocation W20269666281 @default.
• W2026966628 hasLocation W20269666282 @default.
• W2026966628 hasOpenAccess W2026966628 @default.
• W2026966628 hasPrimaryLocation W20269666281 @default.
• W2026966628 hasRelatedWork W122607557 @default.
• W2026966628 hasRelatedWork W1505212356 @default.
• W2026966628 hasRelatedWork W1553966318 @default.
• W2026966628 hasRelatedWork W1954558184 @default.
• W2026966628 hasRelatedWork W1994063413 @default.
• W2026966628 hasRelatedWork W2022367820 @default.
• W2026966628 hasRelatedWork W2056639876 @default.
• W2026966628 hasRelatedWork W2099598908 @default.
• W2026966628 hasRelatedWork W2533209863 @default.
• W2026966628 hasRelatedWork W2800722497 @default.
• W2026966628 hasVolume "135" @default.

• next