FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027040897> ?p ?o ?g. }

• W2027040897 endingPage "196" @default.
• W2027040897 startingPage "187" @default.
• W2027040897 abstract "Following Helicobacter pylori eradication in a placebo-controlled trial, the hypokinesia of idiopathic parkinsonism improved but flexor rigidity worsened.We surveyed the effect of all antimicrobial prescriptions in 66 patients with idiopathic parkinsonism over a median of 1.9 (interquartile range 0.4, 3.5) years. Initial Helicobacter screening was followed (where positive) by gastric biopsy. Serial lactulose hydrogen breath tests (364 tests) for small intestinal bacterial overgrowth monitored the need to encourage fluid intake and bulk/osmotic laxatives. We measured hypokinesia (401 assessments of mean stride length at free walking speed in 58 patients) and upper limb flexor rigidity (396 assessments in 49).Following successful H. pylori eradication (12 cases) but not failed (2), stride increased in entire group (including those receiving levodopa), core group (those receiving only longer-t½ antiparkinsonian medication or untreated) and untreated (p = .001 each case). The effect was greater with less antiparkinsonian medication (19 (95% CI, 14, 25) cm/year in untreated). Flexor rigidity was unchanged. Following antimicrobials for other indications (75 courses), hypokinesia was unchanged. However, flexor rigidity increased cumulatively. It increased in core group only after a first course (by (10 (0, 20)%/year, p = .05)), but then in entire, core and untreated after a second course (18 (6, 31), 33 (19, 48) and 29 (12, 48)%/year respectively; p = .002, .001 and .001) and further still after a third (17 (2, 34), 23 (8, 41) and 38 (15, 65)%/year; p = .02, .003 and .001). Initially, 40/66 were lactulose hydrogen breath test positive. Odds for positivity fell with time (by 59 (46, 75)%/year, p = .001) and tended to be lower with Helicobacter positivity (28 (8, 104)%, p = .06), but were unrelated to other antimicrobial interventions.Improved hypokinesia following antimicrobials appeared unique to Helicobacter eradication. Rigidity increased following successive antimicrobial exposures for other indications, despite diminishing lactulose hydrogen breath test positivity." @default.
• W2027040897 created "2016-06-24" @default.
• W2027040897 creator A5005539896 @default.
• W2027040897 creator A5012449037 @default.
• W2027040897 creator A5014436895 @default.
• W2027040897 creator A5023363391 @default.
• W2027040897 creator A5025017492 @default.
• W2027040897 creator A5052820115 @default.
• W2027040897 creator A5059819677 @default.
• W2027040897 creator A5065866105 @default.
• W2027040897 creator A5068342745 @default.
• W2027040897 date "2013-01-22" @default.
• W2027040897 modified "2023-10-14" @default.
• W2027040897 title "Antimicrobial Surveillance in Idiopathic Parkinsonism: Indication-Specific Improvement in Hypokinesia Following<i>Helicobacter pylori</i>Eradication and Non-Specific Effect of Antimicrobials for Other Indications in Worsening Rigidity" @default.
• W2027040897 cites W1554600569 @default.
• W2027040897 cites W1838461434 @default.
• W2027040897 cites W1966111137 @default.
• W2027040897 cites W1970534639 @default.
• W2027040897 cites W1970710489 @default.
• W2027040897 cites W2012355986 @default.
• W2027040897 cites W2016966976 @default.
• W2027040897 cites W2017421487 @default.
• W2027040897 cites W2034874501 @default.
• W2027040897 cites W2044580180 @default.
• W2027040897 cites W2046214518 @default.
• W2027040897 cites W2048058691 @default.
• W2027040897 cites W2054399253 @default.
• W2027040897 cites W2087581370 @default.
• W2027040897 cites W2094389676 @default.
• W2027040897 cites W2102163881 @default.
• W2027040897 cites W2102476888 @default.
• W2027040897 cites W2104398768 @default.
• W2027040897 cites W2106022949 @default.
• W2027040897 cites W2109424917 @default.
• W2027040897 cites W2118451157 @default.
• W2027040897 cites W2120323573 @default.
• W2027040897 cites W2130540965 @default.
• W2027040897 cites W2134094455 @default.
• W2027040897 cites W2134442010 @default.
• W2027040897 cites W2142483035 @default.
• W2027040897 cites W2142635246 @default.
• W2027040897 cites W2165423666 @default.
• W2027040897 cites W2165976376 @default.
• W2027040897 cites W4322388710 @default.
• W2027040897 doi "https://doi.org/10.1111/hel.12035" @default.
• W2027040897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23336966" @default.
• W2027040897 hasPublicationYear "2013" @default.
• W2027040897 type Work @default.
• W2027040897 sameAs 2027040897 @default.
• W2027040897 citedByCount "33" @default.
• W2027040897 countsByYear W20270408972013 @default.
• W2027040897 countsByYear W20270408972014 @default.
• W2027040897 countsByYear W20270408972015 @default.
• W2027040897 countsByYear W20270408972016 @default.
• W2027040897 countsByYear W20270408972017 @default.
• W2027040897 countsByYear W20270408972018 @default.
• W2027040897 countsByYear W20270408972019 @default.
• W2027040897 countsByYear W20270408972020 @default.
• W2027040897 countsByYear W20270408972021 @default.
• W2027040897 countsByYear W20270408972023 @default.
• W2027040897 crossrefType "journal-article" @default.
• W2027040897 hasAuthorship W2027040897A5005539896 @default.
• W2027040897 hasAuthorship W2027040897A5012449037 @default.
• W2027040897 hasAuthorship W2027040897A5014436895 @default.
• W2027040897 hasAuthorship W2027040897A5023363391 @default.
• W2027040897 hasAuthorship W2027040897A5025017492 @default.
• W2027040897 hasAuthorship W2027040897A5052820115 @default.
• W2027040897 hasAuthorship W2027040897A5059819677 @default.
• W2027040897 hasAuthorship W2027040897A5065866105 @default.
• W2027040897 hasAuthorship W2027040897A5068342745 @default.
• W2027040897 hasConcept C119060515 @default.
• W2027040897 hasConcept C126322002 @default.
• W2027040897 hasConcept C142724271 @default.
• W2027040897 hasConcept C178790620 @default.
• W2027040897 hasConcept C185592680 @default.
• W2027040897 hasConcept C204787440 @default.
• W2027040897 hasConcept C27081682 @default.
• W2027040897 hasConcept C2775880387 @default.
• W2027040897 hasConcept C2776409635 @default.
• W2027040897 hasConcept C2776525014 @default.
• W2027040897 hasConcept C2779134260 @default.
• W2027040897 hasConcept C4937899 @default.
• W2027040897 hasConcept C71924100 @default.
• W2027040897 hasConcept C90924648 @default.
• W2027040897 hasConceptScore W2027040897C119060515 @default.
• W2027040897 hasConceptScore W2027040897C126322002 @default.
• W2027040897 hasConceptScore W2027040897C142724271 @default.
• W2027040897 hasConceptScore W2027040897C178790620 @default.
• W2027040897 hasConceptScore W2027040897C185592680 @default.
• W2027040897 hasConceptScore W2027040897C204787440 @default.
• W2027040897 hasConceptScore W2027040897C27081682 @default.
• W2027040897 hasConceptScore W2027040897C2775880387 @default.
• W2027040897 hasConceptScore W2027040897C2776409635 @default.
• W2027040897 hasConceptScore W2027040897C2776525014 @default.
• W2027040897 hasConceptScore W2027040897C2779134260 @default.
• W2027040897 hasConceptScore W2027040897C4937899 @default.
• W2027040897 hasConceptScore W2027040897C71924100 @default.
• W2027040897 hasConceptScore W2027040897C90924648 @default.

• next