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- W2027131567 abstract "Two novel prenyl 3-benzoxepin derivatives, perilloxin (1) and dehydroperilloxin (2), were isolated from the dichloromethane extract of the stems of Perilla frutescens var. acuta. Their structures were elucidated as (-)-(R)-5-methoxy-2,3-dihydrofuro[2, 3-g][3]benzoxepin and 5-methoxyfuro[2,3-g][3]benzoxepin, respectively, based on UV, MS, (1)H and (13)C NMR, NOE, (1)H-(13)C COSY, and HMBC spectral data. They were isolated following bioassay-guided fractionation, using an in vitro cyclooxygenase-1 test. Compounds 1 and 2 possess inhibitory activities, with IC(50) values of 23.2 microM and 30.4 microM, respectively." @default.
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- W2027131567 date "2000-02-17" @default.
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- W2027131567 title "Two New Prenylated 3-Benzoxepin Derivatives as Cyclooxygenase Inhibitors from <i>Perilla frutescens</i> var. <i>acuta</i>" @default.
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- W2027131567 doi "https://doi.org/10.1021/np990362o" @default.
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