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• W2027156508 abstract "A series of chiral gamma-aryl-1H-1,2,4-triazole derivatives has been synthesized and the respective analogues have been tested for their inhibitory activities against Penicillium digitatum (P. digitatum). In vitro experiments were indicative of a strong inhibitory effect of all of the compounds on P. digitatum, and seven of the compounds 5 exhibited better inhibition than the commercial fungicides triadimefon and triadimenol. The respective pairs of enantiomers showed significantly different inhibitory activities, most notably in the case of 5g-R and 5g-S, for which a 230-fold difference was observed. These observations suggest that P. digitatum discriminates the enantiomers and that the R enantiomer better fits the active site of cytochrome P450." @default.
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• W2027156508 date "2009-07-02" @default.
• W2027156508 modified "2023-10-18" @default.
• W2027156508 title "Determination of Stereoselective Interaction between Enantiomers of Chiral γ-Aryl-1<i>H</i>-1,2,4-triazole Derivatives and <i>Penicillium digitatum</i>" @default.
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• W2027156508 doi "https://doi.org/10.1021/jf901554x" @default.
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