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• W2027223119 endingPage "392" @default.
• W2027223119 startingPage "388" @default.
• W2027223119 abstract "Repairing chromosome breaks is essential to cell survival. A major lethal effect of ionizing radiation (IR) damage is the creation of double-strand DNA breaks. Recently, a number of mammalian cell mutants that are sensitive to IR damage have been described, revealing a unique repair pathway. The DNA-dependent protein kinase (DNA-PK) is necessary for double-strand-break repair and lymphoid V(D)J recombination. DNA-PK consists of three subunits: the Ku autoantigen heterodimer and a kinase (DNA-PKcs) that is deficient in mouse scid mutant cells." @default.
• W2027223119 created "2016-06-24" @default.
• W2027223119 creator A5074838425 @default.
• W2027223119 date "1995-10-01" @default.
• W2027223119 modified "2023-09-30" @default.
• W2027223119 title "What to do at an end: DNA double-strand-break repair" @default.
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• W2027223119 doi "https://doi.org/10.1016/s0168-9525(00)89121-0" @default.
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