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• W2027248259 abstract "The central role of adipose tissue hormone-sensitive lipase in regulating fatty acid metabolism makes it a potential pharmacological target for the prevention of peripheral insulin resistance in obese, prediabetic and diabetic individuals. The synthesis of a new series of carbazates is presented. Modification of the phenolic 4-position in a series of 1,2,3,4-tetrahydroisoquinoline and morpholine derived carbazates, yielded inhibitors of the catalytic activity of this enzyme with nanomolar potency." @default.
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• W2027248259 date "2004-04-01" @default.
• W2027248259 modified "2023-10-11" @default.
• W2027248259 title "Carbazates as potent inhibitors of hormone-sensitive lipase" @default.
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• W2027248259 doi "https://doi.org/10.1016/j.bmcl.2004.01.038" @default.
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