Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027312073> ?p ?o ?g. }
- W2027312073 endingPage "23" @default.
- W2027312073 startingPage "15" @default.
- W2027312073 abstract "Do computational models contribute to progress in mechanobiology? Jacobs and Kelly (in Advances on Modelling in Tissue Engineering, p. 1–14, 2011) suggest that they do, but at the same time propose a limitation in the form of the ‘paradox of validation’, whereby the information needed to validate mechanoregulation theories obviates the need for them in the first place. In this article, the corroboration of theories describing mechanoregulation of tissue differentiation is reviewed. Considering the falsifiability of computational models derived using the theories as a measure of their predictive power, it is shown that the predictive power of some theories is poor and that models based on these theories fall into the ‘paradox of validation’. Week theories for any phenomenon would succumb to such a paradox. We argue that mechanobiology needs theories that can have more potentially falsifying experiments and that perhaps the discipline does suffer from theories that are a priori designed to minimise falsifiability. However, several theories do have predictive power beyond the data used to validate them, so a paradox of validation should disappear as the subject develops." @default.
- W2027312073 created "2016-06-24" @default.
- W2027312073 creator A5021724728 @default.
- W2027312073 creator A5036165760 @default.
- W2027312073 creator A5074735538 @default.
- W2027312073 date "2013-03-15" @default.
- W2027312073 modified "2023-09-23" @default.
- W2027312073 title "Corroboration of computational models for mechanoregulated stem cell differentiation" @default.
- W2027312073 cites W138082360 @default.
- W2027312073 cites W1586391285 @default.
- W2027312073 cites W194176920 @default.
- W2027312073 cites W1964733232 @default.
- W2027312073 cites W1969061860 @default.
- W2027312073 cites W1970237590 @default.
- W2027312073 cites W1974238685 @default.
- W2027312073 cites W1976496131 @default.
- W2027312073 cites W1979137563 @default.
- W2027312073 cites W1984589322 @default.
- W2027312073 cites W1988189846 @default.
- W2027312073 cites W1992397894 @default.
- W2027312073 cites W1992766742 @default.
- W2027312073 cites W2001435165 @default.
- W2027312073 cites W2002369319 @default.
- W2027312073 cites W2003822761 @default.
- W2027312073 cites W2004178281 @default.
- W2027312073 cites W2006437698 @default.
- W2027312073 cites W2007193910 @default.
- W2027312073 cites W2009144332 @default.
- W2027312073 cites W2010041785 @default.
- W2027312073 cites W2010751506 @default.
- W2027312073 cites W2013799545 @default.
- W2027312073 cites W2015102924 @default.
- W2027312073 cites W2015701478 @default.
- W2027312073 cites W2020192461 @default.
- W2027312073 cites W2020963690 @default.
- W2027312073 cites W2028354496 @default.
- W2027312073 cites W2029895410 @default.
- W2027312073 cites W2030474254 @default.
- W2027312073 cites W2030663143 @default.
- W2027312073 cites W2033801063 @default.
- W2027312073 cites W2041633571 @default.
- W2027312073 cites W2041911911 @default.
- W2027312073 cites W2049072682 @default.
- W2027312073 cites W2056471828 @default.
- W2027312073 cites W2057871541 @default.
- W2027312073 cites W2059107467 @default.
- W2027312073 cites W2074870817 @default.
- W2027312073 cites W2079558316 @default.
- W2027312073 cites W2081000153 @default.
- W2027312073 cites W2081106783 @default.
- W2027312073 cites W2089700069 @default.
- W2027312073 cites W2090936021 @default.
- W2027312073 cites W2098385948 @default.
- W2027312073 cites W2100185884 @default.
- W2027312073 cites W2111312751 @default.
- W2027312073 cites W2120761640 @default.
- W2027312073 cites W2121390314 @default.
- W2027312073 cites W2121681341 @default.
- W2027312073 cites W2123389161 @default.
- W2027312073 cites W2128574197 @default.
- W2027312073 cites W2134086845 @default.
- W2027312073 cites W2141841781 @default.
- W2027312073 cites W2143784594 @default.
- W2027312073 cites W2147294049 @default.
- W2027312073 cites W2151011786 @default.
- W2027312073 cites W2153427256 @default.
- W2027312073 cites W2162281037 @default.
- W2027312073 cites W2167388045 @default.
- W2027312073 cites W2321550118 @default.
- W2027312073 cites W2480924511 @default.
- W2027312073 cites W2988868023 @default.
- W2027312073 cites W4249441050 @default.
- W2027312073 doi "https://doi.org/10.1080/10255842.2013.774381" @default.
- W2027312073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23495726" @default.
- W2027312073 hasPublicationYear "2013" @default.
- W2027312073 type Work @default.
- W2027312073 sameAs 2027312073 @default.
- W2027312073 citedByCount "16" @default.
- W2027312073 countsByYear W20273120732014 @default.
- W2027312073 countsByYear W20273120732015 @default.
- W2027312073 countsByYear W20273120732016 @default.
- W2027312073 countsByYear W20273120732017 @default.
- W2027312073 countsByYear W20273120732019 @default.
- W2027312073 countsByYear W20273120732021 @default.
- W2027312073 crossrefType "journal-article" @default.
- W2027312073 hasAuthorship W2027312073A5021724728 @default.
- W2027312073 hasAuthorship W2027312073A5036165760 @default.
- W2027312073 hasAuthorship W2027312073A5074735538 @default.
- W2027312073 hasBestOaLocation W20273120732 @default.
- W2027312073 hasConcept C111472728 @default.
- W2027312073 hasConcept C116222747 @default.
- W2027312073 hasConcept C121332964 @default.
- W2027312073 hasConcept C138885662 @default.
- W2027312073 hasConcept C154945302 @default.
- W2027312073 hasConcept C163258240 @default.
- W2027312073 hasConcept C2522767166 @default.
- W2027312073 hasConcept C2778136018 @default.
- W2027312073 hasConcept C2780171871 @default.