FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027366434> ?p ?o ?g. }

• W2027366434 endingPage "369" @default.
• W2027366434 startingPage "362" @default.
• W2027366434 abstract "The aim of this study was to investigate the extent if recombinant human hyaluronidase (rhuPH20) can enhance trans-scleral penetration of sub-Tenon's dexamethasone (DM) into the posterior segment of the eye.rhuPH20 was purified from conditioned media through a series of ion exchange, hydrophobic interaction, aminophenylboronate, and hydroxyapatite chromatography to greater than 90% purity based upon specific activity. Only the right eye of each rabbit was injected. The first group (n = 16) received an injection of DM and rhuPH20, whereas the second group (n = 16) received DM only. The eyes were enucleated 1, 2, 3, and 6 h after the injection, and the choroid, retina, vitreous, aqueous, and serum were harvested. DM concentration was assessed by mass spectrometry. Histology (n = 2) and immunohistochemistry (n = 2) was performed to detect toxicity and the presence of the rHuPH20, respectively.We observed no histopathologic damage to ocular tissues after sub-Tenon's injection. This enzyme significantly increased DM level in the choroid and the retina 3 h after administration. The rise in levels was transient returning to normal levels by 6 h.Sub-Tenon's coinjection of rHuPH20 with DM resulted in a general increase in DM levels in ocular tissues and the serum, with significant increase in the choroid and the retina, 3 h after administration." @default.
• W2027366434 created "2016-06-24" @default.
• W2027366434 creator A5018155506 @default.
• W2027366434 creator A5039407742 @default.
• W2027366434 creator A5040457654 @default.
• W2027366434 creator A5072298001 @default.
• W2027366434 creator A5073467232 @default.
• W2027366434 creator A5081048810 @default.
• W2027366434 creator A5084185055 @default.
• W2027366434 date "2006-10-01" @default.
• W2027366434 modified "2023-10-03" @default.
• W2027366434 title "The Effect of Recombinant Human Hyaluronidase on Dexamethasone Penetration into the Posterior Segment of the Eye After Sub-Tenon's Injection" @default.
• W2027366434 cites W122692372 @default.
• W2027366434 cites W1964547117 @default.
• W2027366434 cites W1968995676 @default.
• W2027366434 cites W1980440864 @default.
• W2027366434 cites W1986180285 @default.
• W2027366434 cites W1997156360 @default.
• W2027366434 cites W2002627811 @default.
• W2027366434 cites W2004526409 @default.
• W2027366434 cites W2006270519 @default.
• W2027366434 cites W2010804179 @default.
• W2027366434 cites W2020487872 @default.
• W2027366434 cites W2021592080 @default.
• W2027366434 cites W2022275124 @default.
• W2027366434 cites W2031365186 @default.
• W2027366434 cites W2035062994 @default.
• W2027366434 cites W2039214400 @default.
• W2027366434 cites W2059541476 @default.
• W2027366434 cites W2067055244 @default.
• W2027366434 cites W2072184220 @default.
• W2027366434 cites W2086373689 @default.
• W2027366434 cites W2087274504 @default.
• W2027366434 cites W2103863709 @default.
• W2027366434 cites W2149638038 @default.
• W2027366434 cites W2168163081 @default.
• W2027366434 cites W2897172879 @default.
• W2027366434 cites W4247220631 @default.
• W2027366434 doi "https://doi.org/10.1089/jop.2006.22.362" @default.
• W2027366434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17076631" @default.
• W2027366434 hasPublicationYear "2006" @default.
• W2027366434 type Work @default.
• W2027366434 sameAs 2027366434 @default.
• W2027366434 citedByCount "15" @default.
• W2027366434 countsByYear W20273664342012 @default.
• W2027366434 countsByYear W20273664342014 @default.
• W2027366434 countsByYear W20273664342018 @default.
• W2027366434 countsByYear W20273664342020 @default.
• W2027366434 countsByYear W20273664342022 @default.
• W2027366434 countsByYear W20273664342023 @default.
• W2027366434 crossrefType "journal-article" @default.
• W2027366434 hasAuthorship W2027366434A5018155506 @default.
• W2027366434 hasAuthorship W2027366434A5039407742 @default.
• W2027366434 hasAuthorship W2027366434A5040457654 @default.
• W2027366434 hasAuthorship W2027366434A5072298001 @default.
• W2027366434 hasAuthorship W2027366434A5073467232 @default.
• W2027366434 hasAuthorship W2027366434A5081048810 @default.
• W2027366434 hasAuthorship W2027366434A5084185055 @default.
• W2027366434 hasConcept C113520495 @default.
• W2027366434 hasConcept C118487528 @default.
• W2027366434 hasConcept C126322002 @default.
• W2027366434 hasConcept C127413603 @default.
• W2027366434 hasConcept C134018914 @default.
• W2027366434 hasConcept C142724271 @default.
• W2027366434 hasConcept C154049752 @default.
• W2027366434 hasConcept C169760540 @default.
• W2027366434 hasConcept C181199279 @default.
• W2027366434 hasConcept C185592680 @default.
• W2027366434 hasConcept C204232928 @default.
• W2027366434 hasConcept C2776694393 @default.
• W2027366434 hasConcept C2777093970 @default.
• W2027366434 hasConcept C2780375986 @default.
• W2027366434 hasConcept C2780401358 @default.
• W2027366434 hasConcept C29730261 @default.
• W2027366434 hasConcept C42475967 @default.
• W2027366434 hasConcept C55493867 @default.
• W2027366434 hasConcept C66938386 @default.
• W2027366434 hasConcept C71924100 @default.
• W2027366434 hasConcept C80107235 @default.
• W2027366434 hasConcept C86803240 @default.
• W2027366434 hasConceptScore W2027366434C113520495 @default.
• W2027366434 hasConceptScore W2027366434C118487528 @default.
• W2027366434 hasConceptScore W2027366434C126322002 @default.
• W2027366434 hasConceptScore W2027366434C127413603 @default.
• W2027366434 hasConceptScore W2027366434C134018914 @default.
• W2027366434 hasConceptScore W2027366434C142724271 @default.
• W2027366434 hasConceptScore W2027366434C154049752 @default.
• W2027366434 hasConceptScore W2027366434C169760540 @default.
• W2027366434 hasConceptScore W2027366434C181199279 @default.
• W2027366434 hasConceptScore W2027366434C185592680 @default.
• W2027366434 hasConceptScore W2027366434C204232928 @default.
• W2027366434 hasConceptScore W2027366434C2776694393 @default.
• W2027366434 hasConceptScore W2027366434C2777093970 @default.
• W2027366434 hasConceptScore W2027366434C2780375986 @default.
• W2027366434 hasConceptScore W2027366434C2780401358 @default.
• W2027366434 hasConceptScore W2027366434C29730261 @default.
• W2027366434 hasConceptScore W2027366434C42475967 @default.
• W2027366434 hasConceptScore W2027366434C55493867 @default.

• next