FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027424648> ?p ?o ?g. }

• W2027424648 endingPage "325" @default.
• W2027424648 startingPage "311" @default.
• W2027424648 abstract "Over the past decade, our laboratory has developed a secreted heat shock protein (HSP), chaperone gp96, cell-based vaccine that generates effective anti-tumor and anti-infectious immunity in vivo. Gp96-peptide complexes were identified as an extremely efficient stimulator of MHC I-mediated antigen cross-presentation, generating CD8 cytotoxic T-lymphocyte responses detectable in blood, spleen, gut and reproductive tract to femto-molar concentrations of antigen. These studies provided the first evidence that cell-based gp96-Ig-secreting vaccines may serve as a potent modality to induce both systemic and mucosal immunity. This approach takes advantage of the combined adjuvant and antigen delivery capacity of gp96 for the generation of cytotoxic immunity against a wide range of antigens in both anti-vial and anti-cancer vaccination. Here, we review the vaccine design that utilizes the unique property/ability of endoplasmic HSP gp96 to bind antigenic peptides and deliver them to antigen-presenting cells." @default.
• W2027424648 created "2016-06-24" @default.
• W2027424648 creator A5001670202 @default.
• W2027424648 creator A5036159778 @default.
• W2027424648 creator A5066299264 @default.
• W2027424648 creator A5080546814 @default.
• W2027424648 date "2013-11-20" @default.
• W2027424648 modified "2023-10-06" @default.
• W2027424648 title "Secreted heat shock protein gp96-Ig: next-generation vaccines for cancer and infectious diseases" @default.
• W2027424648 cites W1508237796 @default.
• W2027424648 cites W1527986213 @default.
• W2027424648 cites W1540090690 @default.
• W2027424648 cites W1545371216 @default.
• W2027424648 cites W1555650656 @default.
• W2027424648 cites W1569070916 @default.
• W2027424648 cites W1569077405 @default.
• W2027424648 cites W1584629476 @default.
• W2027424648 cites W1585007382 @default.
• W2027424648 cites W1590798843 @default.
• W2027424648 cites W1604363681 @default.
• W2027424648 cites W1658799699 @default.
• W2027424648 cites W1807891428 @default.
• W2027424648 cites W1829400370 @default.
• W2027424648 cites W1963599781 @default.
• W2027424648 cites W1964302896 @default.
• W2027424648 cites W1967138582 @default.
• W2027424648 cites W1967493382 @default.
• W2027424648 cites W1968407403 @default.
• W2027424648 cites W1969066573 @default.
• W2027424648 cites W1969454691 @default.
• W2027424648 cites W1977007393 @default.
• W2027424648 cites W1986373360 @default.
• W2027424648 cites W1986800225 @default.
• W2027424648 cites W1988533351 @default.
• W2027424648 cites W1992689191 @default.
• W2027424648 cites W1993370279 @default.
• W2027424648 cites W1995209114 @default.
• W2027424648 cites W1996520524 @default.
• W2027424648 cites W1997390346 @default.
• W2027424648 cites W1998844140 @default.
• W2027424648 cites W2001015172 @default.
• W2027424648 cites W2001286908 @default.
• W2027424648 cites W2001719540 @default.
• W2027424648 cites W2002704444 @default.
• W2027424648 cites W2006875259 @default.
• W2027424648 cites W2007956498 @default.
• W2027424648 cites W2011958996 @default.
• W2027424648 cites W2012588209 @default.
• W2027424648 cites W2013090484 @default.
• W2027424648 cites W2014287557 @default.
• W2027424648 cites W2019505133 @default.
• W2027424648 cites W2028243344 @default.
• W2027424648 cites W2035862592 @default.
• W2027424648 cites W2038204417 @default.
• W2027424648 cites W2040850093 @default.
• W2027424648 cites W2041299145 @default.
• W2027424648 cites W2041560123 @default.
• W2027424648 cites W2045848719 @default.
• W2027424648 cites W2046061359 @default.
• W2027424648 cites W2046972425 @default.
• W2027424648 cites W2047900555 @default.
• W2027424648 cites W2048800818 @default.
• W2027424648 cites W2051793369 @default.
• W2027424648 cites W2052316630 @default.
• W2027424648 cites W2055068323 @default.
• W2027424648 cites W2056086531 @default.
• W2027424648 cites W2061912829 @default.
• W2027424648 cites W2062786967 @default.
• W2027424648 cites W2063982677 @default.
• W2027424648 cites W2064162658 @default.
• W2027424648 cites W2070128430 @default.
• W2027424648 cites W2070491512 @default.
• W2027424648 cites W2073905541 @default.
• W2027424648 cites W2077006408 @default.
• W2027424648 cites W2079594954 @default.
• W2027424648 cites W2079746230 @default.
• W2027424648 cites W2080335579 @default.
• W2027424648 cites W2083155294 @default.
• W2027424648 cites W2086454098 @default.
• W2027424648 cites W2088481746 @default.
• W2027424648 cites W2090317414 @default.
• W2027424648 cites W2091534434 @default.
• W2027424648 cites W2094605832 @default.
• W2027424648 cites W2097373411 @default.
• W2027424648 cites W2098983864 @default.
• W2027424648 cites W2099735866 @default.
• W2027424648 cites W2101163432 @default.
• W2027424648 cites W2101189282 @default.
• W2027424648 cites W2103872250 @default.
• W2027424648 cites W2104501624 @default.
• W2027424648 cites W2105501602 @default.
• W2027424648 cites W2109648512 @default.
• W2027424648 cites W2110064348 @default.
• W2027424648 cites W2112530895 @default.
• W2027424648 cites W2112913637 @default.
• W2027424648 cites W2117346210 @default.
• W2027424648 cites W2118891938 @default.
• W2027424648 cites W2119063754 @default.

• next