Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027431873> ?p ?o ?g. }
- W2027431873 abstract "In the present study, we evaluated the possible regulation by alpha 2-receptor agonists (SKF 35886 and UK 14304) of peptide release and functional responses upon sensory nerve activation in the guinea-pig lung. The peptide release and bronchoconstriction caused by antidromic vagal nerve stimulation (low frequency, 1 Hz), and a low concentration of capsaicin (10(-8) M) and resiniferatoxin (3 x 10(-10) M) were attenuated by alpha 2-adrenoceptor agonists. The effects of capsaicin and nicotine in high concentrations and high frequency nerve stimulation (10 Hz) were influenced to a much smaller extent by alpha 2-adrenoceptor stimulation. The calcitonin gene-related peptide release evoked by bradykinin but not the functional effects was inhibited by alpha 2-adrenoceptor activation. It is concluded that alpha 2-adrenoceptor stimulation mainly inhibits the release of mediator and/or the bronchoconstriction caused by moderate activation of sensory nerves. It is necessary to measure mediator release directly to reveal prejunctional effects and not to rely only on indirect functional evidence." @default.
- W2027431873 created "2016-06-24" @default.
- W2027431873 creator A5013543425 @default.
- W2027431873 creator A5047897533 @default.
- W2027431873 creator A5073530795 @default.
- W2027431873 date "1992-01-01" @default.
- W2027431873 modified "2023-10-01" @default.
- W2027431873 title "Variable α2-adrenoceptor-mediated inhibition of bronchoconstriction and peptide release upon activation of pulmonary afferents" @default.
- W2027431873 cites W1531423968 @default.
- W2027431873 cites W1971845958 @default.
- W2027431873 cites W1973870619 @default.
- W2027431873 cites W1976368911 @default.
- W2027431873 cites W1981761340 @default.
- W2027431873 cites W1982319804 @default.
- W2027431873 cites W1982861623 @default.
- W2027431873 cites W1988534852 @default.
- W2027431873 cites W1997324177 @default.
- W2027431873 cites W2005146250 @default.
- W2027431873 cites W2006875910 @default.
- W2027431873 cites W2012389728 @default.
- W2027431873 cites W2018668714 @default.
- W2027431873 cites W2036929503 @default.
- W2027431873 cites W2043443433 @default.
- W2027431873 cites W2052713228 @default.
- W2027431873 cites W2054772097 @default.
- W2027431873 cites W2063573379 @default.
- W2027431873 cites W2066738932 @default.
- W2027431873 cites W2066826979 @default.
- W2027431873 cites W2077300365 @default.
- W2027431873 cites W2077663629 @default.
- W2027431873 cites W2079422914 @default.
- W2027431873 cites W2081671752 @default.
- W2027431873 cites W2084414745 @default.
- W2027431873 cites W2086758144 @default.
- W2027431873 cites W2096896478 @default.
- W2027431873 cites W2113895167 @default.
- W2027431873 cites W2268809465 @default.
- W2027431873 cites W2412497480 @default.
- W2027431873 cites W2414424124 @default.
- W2027431873 cites W2430733551 @default.
- W2027431873 cites W72363943 @default.
- W2027431873 doi "https://doi.org/10.1016/0014-2999(92)90668-t" @default.
- W2027431873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1350992" @default.
- W2027431873 hasPublicationYear "1992" @default.
- W2027431873 type Work @default.
- W2027431873 sameAs 2027431873 @default.
- W2027431873 citedByCount "26" @default.
- W2027431873 countsByYear W20274318732017 @default.
- W2027431873 crossrefType "journal-article" @default.
- W2027431873 hasAuthorship W2027431873A5013543425 @default.
- W2027431873 hasAuthorship W2027431873A5047897533 @default.
- W2027431873 hasAuthorship W2027431873A5073530795 @default.
- W2027431873 hasConcept C126322002 @default.
- W2027431873 hasConcept C134018914 @default.
- W2027431873 hasConcept C155164980 @default.
- W2027431873 hasConcept C160145004 @default.
- W2027431873 hasConcept C169760540 @default.
- W2027431873 hasConcept C170493617 @default.
- W2027431873 hasConcept C185592680 @default.
- W2027431873 hasConcept C24998067 @default.
- W2027431873 hasConcept C2775907655 @default.
- W2027431873 hasConcept C2776042228 @default.
- W2027431873 hasConcept C2776354303 @default.
- W2027431873 hasConcept C2778938600 @default.
- W2027431873 hasConcept C2779591629 @default.
- W2027431873 hasConcept C2780051329 @default.
- W2027431873 hasConcept C2780769369 @default.
- W2027431873 hasConcept C70471684 @default.
- W2027431873 hasConcept C71924100 @default.
- W2027431873 hasConcept C86803240 @default.
- W2027431873 hasConcept C94487597 @default.
- W2027431873 hasConceptScore W2027431873C126322002 @default.
- W2027431873 hasConceptScore W2027431873C134018914 @default.
- W2027431873 hasConceptScore W2027431873C155164980 @default.
- W2027431873 hasConceptScore W2027431873C160145004 @default.
- W2027431873 hasConceptScore W2027431873C169760540 @default.
- W2027431873 hasConceptScore W2027431873C170493617 @default.
- W2027431873 hasConceptScore W2027431873C185592680 @default.
- W2027431873 hasConceptScore W2027431873C24998067 @default.
- W2027431873 hasConceptScore W2027431873C2775907655 @default.
- W2027431873 hasConceptScore W2027431873C2776042228 @default.
- W2027431873 hasConceptScore W2027431873C2776354303 @default.
- W2027431873 hasConceptScore W2027431873C2778938600 @default.
- W2027431873 hasConceptScore W2027431873C2779591629 @default.
- W2027431873 hasConceptScore W2027431873C2780051329 @default.
- W2027431873 hasConceptScore W2027431873C2780769369 @default.
- W2027431873 hasConceptScore W2027431873C70471684 @default.
- W2027431873 hasConceptScore W2027431873C71924100 @default.
- W2027431873 hasConceptScore W2027431873C86803240 @default.
- W2027431873 hasConceptScore W2027431873C94487597 @default.
- W2027431873 hasLocation W20274318731 @default.
- W2027431873 hasLocation W20274318732 @default.
- W2027431873 hasOpenAccess W2027431873 @default.
- W2027431873 hasPrimaryLocation W20274318731 @default.
- W2027431873 hasRelatedWork W147574517 @default.
- W2027431873 hasRelatedWork W1998342669 @default.
- W2027431873 hasRelatedWork W2018646869 @default.
- W2027431873 hasRelatedWork W2027431873 @default.
- W2027431873 hasRelatedWork W2066826979 @default.
- W2027431873 hasRelatedWork W2092188367 @default.