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• W2027436851 abstract "Solar ultraviolet (UV) radiation during the summer and vitamin D supplementation are two major sources of vitamin D for humans at northern latitudes. However, little is known about the relative efficiency of these two vitamin D sources. The main goal was to compare the efficiency of high‐dose oral vitamin D3 supplementation (2000 IU per day for 30 days) with a simulated summer UV exposure [10 sunbed sessions to a total dose of 23·8 standard erythema doses (SED)] to improve vitamin D status. Healthy volunteers were randomized into two groups: group 1 received vitamin D supplementation followed by 10 whole‐body sunbed exposures; group 2 started with 10 sunbed exposures followed by vitamin D supplementation. The oral supplementation with vitamin D3 resulted in a mean (SEM) serum 25‐hydroxyvitamin D [25(OH)D] increase of 25·3 (5·4) nmol L−1. A similar increase, 19·8 (5·4) nmol L−1, was observed after simulated summer UV exposure. At the end of the study, serum 25(OH)D concentrations were similar in both groups. Twice‐weekly whole‐body sunbed exposure to a dose of 4·8 SED is equal to 2000 IU daily of oral vitamin D supplementation for 30 days and enough to achieve and maintain serum 25(OH)D concentrations > 75 nmol L−1 in ~55% of cases. Based on our calculations, this dose corresponds to a cumulative weekly whole‐body exposure of 3·4 SED (~ 40 min around midday during the summer at the latitude of Oslo)." @default.
• W2027436851 created "2016-06-24" @default.
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• W2027436851 date "2013-08-01" @default.
• W2027436851 modified "2023-09-25" @default.
• W2027436851 title "Effect of vitamin D supplementation and ultraviolet B exposure on serum 25-hydroxyvitamin D concentrations in healthy volunteers: a randomized, crossover clinical trial" @default.
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• W2027436851 doi "https://doi.org/10.1111/bjd.12349" @default.
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