Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027468478> ?p ?o ?g. }
- W2027468478 endingPage "212" @default.
- W2027468478 startingPage "207" @default.
- W2027468478 abstract "Granulomas, the pathologic hallmarks of tuberculosis, are composed of tightly numerous immune cells that respond to a variety of persistent stimuli during pathogen-host interaction. The granuloma is essential for host containment of mycobacterial infection, however, the mechanism of host and pathogen determinants to recruit immune cells at the site of inflammation and the formation of granulomas remains elusive until now. Macrophage migration inhibitory factor (MIF), a cytokine produced by many cell types, modulates cellular and humoral immune responses and promote lymphocytes migration to the site of infection. In this study, we evaluate the expression of MIF in tuberculous granulomas by three different models of diseases: mouse, human tissues and zebrafish. The overall results demonstrated that the expression of MIF positive signals markedly increased in the tissues which have been infected with mycobacterium, whereas a few presence of MIF in the PBS-treated animals (means the control group). In the mycobacterial-infected animals, the MIF positives distributed extensively within the granuloma especially in the multinucleated giant cells. Thus, three independent lines of evidence support the hypothesis that MIF may be an important player in aggregate immune cells to the granuloma microenvironments in these animal models of tuberculosis." @default.
- W2027468478 created "2016-06-24" @default.
- W2027468478 creator A5023074105 @default.
- W2027468478 creator A5023857301 @default.
- W2027468478 creator A5039448468 @default.
- W2027468478 creator A5041721852 @default.
- W2027468478 creator A5053863846 @default.
- W2027468478 creator A5054498344 @default.
- W2027468478 creator A5054661910 @default.
- W2027468478 creator A5069879150 @default.
- W2027468478 creator A5077484550 @default.
- W2027468478 date "2012-10-01" @default.
- W2027468478 modified "2023-09-25" @default.
- W2027468478 title "Increased density of macrophage migration inhibitory factor (MIF) in tuberculosis granuloma" @default.
- W2027468478 cites W1540323116 @default.
- W2027468478 cites W1577799117 @default.
- W2027468478 cites W1965101459 @default.
- W2027468478 cites W1965850598 @default.
- W2027468478 cites W1965900626 @default.
- W2027468478 cites W1969623044 @default.
- W2027468478 cites W1970984991 @default.
- W2027468478 cites W1976575734 @default.
- W2027468478 cites W1986837253 @default.
- W2027468478 cites W1989832114 @default.
- W2027468478 cites W1993738876 @default.
- W2027468478 cites W1995910069 @default.
- W2027468478 cites W1997325352 @default.
- W2027468478 cites W1997325736 @default.
- W2027468478 cites W1998634876 @default.
- W2027468478 cites W2001634895 @default.
- W2027468478 cites W2001801137 @default.
- W2027468478 cites W2018487529 @default.
- W2027468478 cites W2020036314 @default.
- W2027468478 cites W2058270697 @default.
- W2027468478 cites W2062824264 @default.
- W2027468478 cites W2064964564 @default.
- W2027468478 cites W2070575526 @default.
- W2027468478 cites W2071723955 @default.
- W2027468478 cites W2077008732 @default.
- W2027468478 cites W2082017122 @default.
- W2027468478 cites W2082470331 @default.
- W2027468478 cites W2086227247 @default.
- W2027468478 cites W2087968772 @default.
- W2027468478 cites W2090056328 @default.
- W2027468478 cites W2104994013 @default.
- W2027468478 cites W2126600660 @default.
- W2027468478 cites W2144005760 @default.
- W2027468478 cites W2144278530 @default.
- W2027468478 cites W2155935320 @default.
- W2027468478 cites W2158014788 @default.
- W2027468478 cites W2167904859 @default.
- W2027468478 cites W2342153330 @default.
- W2027468478 doi "https://doi.org/10.1016/j.yexmp.2012.05.004" @default.
- W2027468478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22609310" @default.
- W2027468478 hasPublicationYear "2012" @default.
- W2027468478 type Work @default.
- W2027468478 sameAs 2027468478 @default.
- W2027468478 citedByCount "5" @default.
- W2027468478 countsByYear W20274684782014 @default.
- W2027468478 countsByYear W20274684782016 @default.
- W2027468478 countsByYear W20274684782017 @default.
- W2027468478 countsByYear W20274684782018 @default.
- W2027468478 countsByYear W20274684782022 @default.
- W2027468478 crossrefType "journal-article" @default.
- W2027468478 hasAuthorship W2027468478A5023074105 @default.
- W2027468478 hasAuthorship W2027468478A5023857301 @default.
- W2027468478 hasAuthorship W2027468478A5039448468 @default.
- W2027468478 hasAuthorship W2027468478A5041721852 @default.
- W2027468478 hasAuthorship W2027468478A5053863846 @default.
- W2027468478 hasAuthorship W2027468478A5054498344 @default.
- W2027468478 hasAuthorship W2027468478A5054661910 @default.
- W2027468478 hasAuthorship W2027468478A5069879150 @default.
- W2027468478 hasAuthorship W2027468478A5077484550 @default.
- W2027468478 hasConcept C104177226 @default.
- W2027468478 hasConcept C142724271 @default.
- W2027468478 hasConcept C202751555 @default.
- W2027468478 hasConcept C203014093 @default.
- W2027468478 hasConcept C2776914184 @default.
- W2027468478 hasConcept C2777975735 @default.
- W2027468478 hasConcept C2778690821 @default.
- W2027468478 hasConcept C2779244956 @default.
- W2027468478 hasConcept C2780140890 @default.
- W2027468478 hasConcept C2781069245 @default.
- W2027468478 hasConcept C54355233 @default.
- W2027468478 hasConcept C55493867 @default.
- W2027468478 hasConcept C71924100 @default.
- W2027468478 hasConcept C77076574 @default.
- W2027468478 hasConcept C86803240 @default.
- W2027468478 hasConcept C8891405 @default.
- W2027468478 hasConceptScore W2027468478C104177226 @default.
- W2027468478 hasConceptScore W2027468478C142724271 @default.
- W2027468478 hasConceptScore W2027468478C202751555 @default.
- W2027468478 hasConceptScore W2027468478C203014093 @default.
- W2027468478 hasConceptScore W2027468478C2776914184 @default.
- W2027468478 hasConceptScore W2027468478C2777975735 @default.
- W2027468478 hasConceptScore W2027468478C2778690821 @default.
- W2027468478 hasConceptScore W2027468478C2779244956 @default.
- W2027468478 hasConceptScore W2027468478C2780140890 @default.