Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027468968> ?p ?o ?g. }
- W2027468968 endingPage "e1002219" @default.
- W2027468968 startingPage "e1002219" @default.
- W2027468968 abstract "Bursaphelenchus xylophilus is the nematode responsible for a devastating epidemic of pine wilt disease in Asia and Europe, and represents a recent, independent origin of plant parasitism in nematodes, ecologically and taxonomically distinct from other nematodes for which genomic data is available. As well as being an important pathogen, the B. xylophilus genome thus provides a unique opportunity to study the evolution and mechanism of plant parasitism. Here, we present a high-quality draft genome sequence from an inbred line of B. xylophilus, and use this to investigate the biological basis of its complex ecology which combines fungal feeding, plant parasitic and insect-associated stages. We focus particularly on putative parasitism genes as well as those linked to other key biological processes and demonstrate that B. xylophilus is well endowed with RNA interference effectors, peptidergic neurotransmitters (including the first description of ins genes in a parasite) stress response and developmental genes and has a contracted set of chemosensory receptors. B. xylophilus has the largest number of digestive proteases known for any nematode and displays expanded families of lysosome pathway genes, ABC transporters and cytochrome P450 pathway genes. This expansion in digestive and detoxification proteins may reflect the unusual diversity in foods it exploits and environments it encounters during its life cycle. In addition, B. xylophilus possesses a unique complement of plant cell wall modifying proteins acquired by horizontal gene transfer, underscoring the impact of this process on the evolution of plant parasitism by nematodes. Together with the lack of proteins homologous to effectors from other plant parasitic nematodes, this confirms the distinctive molecular basis of plant parasitism in the Bursaphelenchus lineage. The genome sequence of B. xylophilus adds to the diversity of genomic data for nematodes, and will be an important resource in understanding the biology of this unusual parasite." @default.
- W2027468968 created "2016-06-24" @default.
- W2027468968 creator A5000296333 @default.
- W2027468968 creator A5004949180 @default.
- W2027468968 creator A5005070550 @default.
- W2027468968 creator A5008688272 @default.
- W2027468968 creator A5010597878 @default.
- W2027468968 creator A5013282022 @default.
- W2027468968 creator A5016868993 @default.
- W2027468968 creator A5026207705 @default.
- W2027468968 creator A5026844020 @default.
- W2027468968 creator A5027921257 @default.
- W2027468968 creator A5028847736 @default.
- W2027468968 creator A5032854994 @default.
- W2027468968 creator A5034286182 @default.
- W2027468968 creator A5035440708 @default.
- W2027468968 creator A5037546216 @default.
- W2027468968 creator A5042277529 @default.
- W2027468968 creator A5051406444 @default.
- W2027468968 creator A5053101311 @default.
- W2027468968 creator A5053994352 @default.
- W2027468968 creator A5063393401 @default.
- W2027468968 creator A5068541745 @default.
- W2027468968 creator A5086519706 @default.
- W2027468968 date "2011-09-01" @default.
- W2027468968 modified "2023-10-10" @default.
- W2027468968 title "Genomic Insights into the Origin of Parasitism in the Emerging Plant Pathogen Bursaphelenchus xylophilus" @default.
- W2027468968 cites W1484347389 @default.
- W2027468968 cites W1569358416 @default.
- W2027468968 cites W1694218737 @default.
- W2027468968 cites W1921170998 @default.
- W2027468968 cites W1967213093 @default.
- W2027468968 cites W1974116356 @default.
- W2027468968 cites W1978402550 @default.
- W2027468968 cites W1978532974 @default.
- W2027468968 cites W1980133202 @default.
- W2027468968 cites W1985792292 @default.
- W2027468968 cites W1996700726 @default.
- W2027468968 cites W2000338604 @default.
- W2027468968 cites W2001521757 @default.
- W2027468968 cites W2002751165 @default.
- W2027468968 cites W2004447254 @default.
- W2027468968 cites W2005540741 @default.
- W2027468968 cites W2005908916 @default.
- W2027468968 cites W2007378492 @default.
- W2027468968 cites W2008856488 @default.
- W2027468968 cites W2011889807 @default.
- W2027468968 cites W2016121195 @default.
- W2027468968 cites W2022871850 @default.
- W2027468968 cites W2028350602 @default.
- W2027468968 cites W2032061227 @default.
- W2027468968 cites W2033153879 @default.
- W2027468968 cites W2035252635 @default.
- W2027468968 cites W2039485752 @default.
- W2027468968 cites W2039883975 @default.
- W2027468968 cites W2045446243 @default.
- W2027468968 cites W2050815579 @default.
- W2027468968 cites W2053927782 @default.
- W2027468968 cites W2057558367 @default.
- W2027468968 cites W2060584475 @default.
- W2027468968 cites W2065974272 @default.
- W2027468968 cites W2070487561 @default.
- W2027468968 cites W2075622722 @default.
- W2027468968 cites W2075925574 @default.
- W2027468968 cites W2079040627 @default.
- W2027468968 cites W2081583449 @default.
- W2027468968 cites W2084274022 @default.
- W2027468968 cites W2089047063 @default.
- W2027468968 cites W2091448229 @default.
- W2027468968 cites W2099333915 @default.
- W2027468968 cites W2100450322 @default.
- W2027468968 cites W2101786683 @default.
- W2027468968 cites W2102776218 @default.
- W2027468968 cites W2105106534 @default.
- W2027468968 cites W2108108770 @default.
- W2027468968 cites W2108489839 @default.
- W2027468968 cites W2108787198 @default.
- W2027468968 cites W2110835349 @default.
- W2027468968 cites W2112568073 @default.
- W2027468968 cites W2114641997 @default.
- W2027468968 cites W2119900532 @default.
- W2027468968 cites W2124661861 @default.
- W2027468968 cites W2125121305 @default.
- W2027468968 cites W2132333544 @default.
- W2027468968 cites W2132449694 @default.
- W2027468968 cites W2132926880 @default.
- W2027468968 cites W2133790305 @default.
- W2027468968 cites W2141157287 @default.
- W2027468968 cites W2144008452 @default.
- W2027468968 cites W2146602601 @default.
- W2027468968 cites W2152770371 @default.
- W2027468968 cites W2156095709 @default.
- W2027468968 cites W2157772863 @default.
- W2027468968 cites W2159033700 @default.
- W2027468968 cites W2160053034 @default.
- W2027468968 cites W2160969485 @default.
- W2027468968 cites W2168200296 @default.
- W2027468968 cites W2168696662 @default.