Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027514832> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2027514832 endingPage "545" @default.
- W2027514832 startingPage "539" @default.
- W2027514832 abstract "To investigate the change of DNA content and the effect of synthetic phase (S-phase) fraction on hepatocytes and hepatomas, DNA content and S-phase fraction were measured by flow cytometry in human livers and hepatoma tissues. The ploidy status of nontumor parts of resected hepatoma, fetal liver, and focal nodular hyperplasia were diploid, similar to that of the normal liver. Three patterns of DNA ploidy in human hepatoma cells were newly classified, namely, pattern I, diploid tumors; pattern II, aneuploid tumors with single G0/G1 peak; and pattern III, aneuploid tumors with more than one G0/G1 peaks. Among the 130 resectable hepatomas measured for DNA ploidy status, 84 (64.6%) were pattern I, 20 (15.4%) pattern II, and 26 (20%) pattern III. Multivariate analyses for those 130 patients who underwent hepatic resection showed that, in addition to tumor size, DNA ploidy was another prognostic factor in predicting overall survival and disease-free survival. Patients with small tumors (less than 5 cm) had a significantly higher overall survival rate than those with large tumor (greater than 5 cm). Patients with pattern III hepatomas had a significantly lower overall survival rate and a higher recurrent rate than did those with pattern I or pattern II tumors. The S-phase fraction was a significant predictor of overall survival rate in patients with pattern II, but not with pattern I, tumors. We conclude that DNA flow-cytometric measurements of ploidy and S-phase fraction are potential important prognostic predictors in patients with resectable hepatomas." @default.
- W2027514832 created "2016-06-24" @default.
- W2027514832 creator A5000562074 @default.
- W2027514832 creator A5007851918 @default.
- W2027514832 creator A5016453981 @default.
- W2027514832 creator A5023998531 @default.
- W2027514832 creator A5047675761 @default.
- W2027514832 date "1992-02-01" @default.
- W2027514832 modified "2023-10-16" @default.
- W2027514832 title "Prediction of relapse or survival after resection in human hepatomas by DNA flow cytometry." @default.
- W2027514832 cites W1523865880 @default.
- W2027514832 cites W1940981239 @default.
- W2027514832 cites W1970719688 @default.
- W2027514832 cites W1976998591 @default.
- W2027514832 cites W1980438510 @default.
- W2027514832 cites W1989169468 @default.
- W2027514832 cites W2002795519 @default.
- W2027514832 cites W2006454988 @default.
- W2027514832 cites W2029367423 @default.
- W2027514832 cites W2050830722 @default.
- W2027514832 cites W2058992557 @default.
- W2027514832 cites W2060508297 @default.
- W2027514832 cites W2065595934 @default.
- W2027514832 cites W2071202950 @default.
- W2027514832 cites W2072679601 @default.
- W2027514832 cites W2084063599 @default.
- W2027514832 cites W2084178599 @default.
- W2027514832 cites W2155485025 @default.
- W2027514832 cites W2328982008 @default.
- W2027514832 cites W2405805007 @default.
- W2027514832 cites W2409826182 @default.
- W2027514832 doi "https://doi.org/10.1172/jci115618" @default.
- W2027514832 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/442885" @default.
- W2027514832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1310697" @default.
- W2027514832 hasPublicationYear "1992" @default.
- W2027514832 type Work @default.
- W2027514832 sameAs 2027514832 @default.
- W2027514832 citedByCount "49" @default.
- W2027514832 countsByYear W20275148322012 @default.
- W2027514832 countsByYear W20275148322016 @default.
- W2027514832 countsByYear W20275148322017 @default.
- W2027514832 crossrefType "journal-article" @default.
- W2027514832 hasAuthorship W2027514832A5000562074 @default.
- W2027514832 hasAuthorship W2027514832A5007851918 @default.
- W2027514832 hasAuthorship W2027514832A5016453981 @default.
- W2027514832 hasAuthorship W2027514832A5023998531 @default.
- W2027514832 hasAuthorship W2027514832A5047675761 @default.
- W2027514832 hasBestOaLocation W20275148321 @default.
- W2027514832 hasConcept C104317684 @default.
- W2027514832 hasConcept C126322002 @default.
- W2027514832 hasConcept C142724271 @default.
- W2027514832 hasConcept C143191323 @default.
- W2027514832 hasConcept C153911025 @default.
- W2027514832 hasConcept C2776283816 @default.
- W2027514832 hasConcept C2779672484 @default.
- W2027514832 hasConcept C30481170 @default.
- W2027514832 hasConcept C502942594 @default.
- W2027514832 hasConcept C54355233 @default.
- W2027514832 hasConcept C552990157 @default.
- W2027514832 hasConcept C553184892 @default.
- W2027514832 hasConcept C71924100 @default.
- W2027514832 hasConcept C86803240 @default.
- W2027514832 hasConceptScore W2027514832C104317684 @default.
- W2027514832 hasConceptScore W2027514832C126322002 @default.
- W2027514832 hasConceptScore W2027514832C142724271 @default.
- W2027514832 hasConceptScore W2027514832C143191323 @default.
- W2027514832 hasConceptScore W2027514832C153911025 @default.
- W2027514832 hasConceptScore W2027514832C2776283816 @default.
- W2027514832 hasConceptScore W2027514832C2779672484 @default.
- W2027514832 hasConceptScore W2027514832C30481170 @default.
- W2027514832 hasConceptScore W2027514832C502942594 @default.
- W2027514832 hasConceptScore W2027514832C54355233 @default.
- W2027514832 hasConceptScore W2027514832C552990157 @default.
- W2027514832 hasConceptScore W2027514832C553184892 @default.
- W2027514832 hasConceptScore W2027514832C71924100 @default.
- W2027514832 hasConceptScore W2027514832C86803240 @default.
- W2027514832 hasIssue "2" @default.
- W2027514832 hasLocation W20275148321 @default.
- W2027514832 hasLocation W20275148322 @default.
- W2027514832 hasLocation W20275148323 @default.
- W2027514832 hasLocation W20275148324 @default.
- W2027514832 hasOpenAccess W2027514832 @default.
- W2027514832 hasPrimaryLocation W20275148321 @default.
- W2027514832 hasRelatedWork W1970446973 @default.
- W2027514832 hasRelatedWork W1970758615 @default.
- W2027514832 hasRelatedWork W2042987274 @default.
- W2027514832 hasRelatedWork W2047624958 @default.
- W2027514832 hasRelatedWork W2075601868 @default.
- W2027514832 hasRelatedWork W2083313910 @default.
- W2027514832 hasRelatedWork W2372106946 @default.
- W2027514832 hasRelatedWork W2396168437 @default.
- W2027514832 hasRelatedWork W2421341418 @default.
- W2027514832 hasRelatedWork W4309168067 @default.
- W2027514832 hasVolume "89" @default.
- W2027514832 isParatext "false" @default.
- W2027514832 isRetracted "false" @default.
- W2027514832 magId "2027514832" @default.
- W2027514832 workType "article" @default.