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- W2027519348 abstract "Intraperitoneal administration of atropine sulfate and atropine methyl nitrate (3, 6, 9 mg/kg) decreased schedule-induced polydipsia as a function of increasing drug dosage. Physiological saline had no effect. Of the two anticholinergic drugs administered, atropine sulfate attenuated the polydipsic response more effectively. It was concluded that schedule-induced polydipsia, like other types of excessive drinking (e.g. chemical, deprivation and salt induced drinking) is mediated, at least in part, by cholinergic neural pathways. Some drug effect on eating was observed, particularly following atropine methyl nitrate, but control data indicated that any effects on eating were secondary, and related to anticholinergic effect upon water intake and salivation." @default.
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- W2027519348 date "1970-06-01" @default.
- W2027519348 modified "2023-09-23" @default.
- W2027519348 title "Anticholinergic blockade of schedule-induced polydipsia" @default.
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- W2027519348 doi "https://doi.org/10.1016/0031-9384(70)90222-2" @default.
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