Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027568716> ?p ?o ?g. }
- W2027568716 endingPage "286" @default.
- W2027568716 startingPage "279" @default.
- W2027568716 abstract "Three different calmodulin genes that encode the same protein have been found in the brain of all mammalian species so far examined. Little is known about the factors involved in regulating the expression of this gene family in the central nervous system. We have investigated the possibility of differential expression of two calmodulin genes, CaM I and CaM II, which are expressed strongly in neuronal cells in the adult rat brain, after treatment with the γ (lindane) and the S isomers of the hexachlorocyclohexane (HCH). In this study a decrease of CaM I mRNA (mainly in the 4.0 kb transcript) was found in the cortex of the rats after 24 h of isomer administration. CaM I expression seemed to be more sensitive to S isomer action, whereas the γ isomer acted mainly at CaM II level. The levels of mRNA of calmodulin CaM II gene were also found to decrease after lindane administration; S-HCH produced an increase of this transcript. These results were obtained by Northern blot analysis and confirmed by means of in situ hybridization. Our results suggest that levels of neuronal calmodulin mRNA species are modified in response to changes in neuronal activity." @default.
- W2027568716 created "2016-06-24" @default.
- W2027568716 creator A5007363668 @default.
- W2027568716 creator A5036772541 @default.
- W2027568716 creator A5080274904 @default.
- W2027568716 date "1995-06-01" @default.
- W2027568716 modified "2023-09-27" @default.
- W2027568716 title "Effect of hexachlorocyclohexane isomers on calmodulin mRNA expression in the central nervous system" @default.
- W2027568716 cites W1535914904 @default.
- W2027568716 cites W1544043865 @default.
- W2027568716 cites W1558731290 @default.
- W2027568716 cites W1564556915 @default.
- W2027568716 cites W1608453530 @default.
- W2027568716 cites W1967424249 @default.
- W2027568716 cites W1980201371 @default.
- W2027568716 cites W1980876268 @default.
- W2027568716 cites W1985587671 @default.
- W2027568716 cites W1985764367 @default.
- W2027568716 cites W2000501104 @default.
- W2027568716 cites W2005851086 @default.
- W2027568716 cites W2012974904 @default.
- W2027568716 cites W2014669590 @default.
- W2027568716 cites W2018202574 @default.
- W2027568716 cites W2024962078 @default.
- W2027568716 cites W2025931980 @default.
- W2027568716 cites W2026725342 @default.
- W2027568716 cites W2028318252 @default.
- W2027568716 cites W2032785814 @default.
- W2027568716 cites W2039651670 @default.
- W2027568716 cites W2058117251 @default.
- W2027568716 cites W2058552999 @default.
- W2027568716 cites W2063585944 @default.
- W2027568716 cites W206588626 @default.
- W2027568716 cites W2066166249 @default.
- W2027568716 cites W2072303293 @default.
- W2027568716 cites W2074855486 @default.
- W2027568716 cites W2078578832 @default.
- W2027568716 cites W2080521355 @default.
- W2027568716 cites W2080532845 @default.
- W2027568716 cites W2081724775 @default.
- W2027568716 cites W2086098750 @default.
- W2027568716 cites W2089900405 @default.
- W2027568716 cites W2091153738 @default.
- W2027568716 cites W2095119066 @default.
- W2027568716 cites W2104953808 @default.
- W2027568716 cites W2129965047 @default.
- W2027568716 cites W2139834955 @default.
- W2027568716 cites W2161061374 @default.
- W2027568716 cites W2167251354 @default.
- W2027568716 doi "https://doi.org/10.1016/0169-328x(95)00015-k" @default.
- W2027568716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7543649" @default.
- W2027568716 hasPublicationYear "1995" @default.
- W2027568716 type Work @default.
- W2027568716 sameAs 2027568716 @default.
- W2027568716 citedByCount "17" @default.
- W2027568716 countsByYear W20275687162017 @default.
- W2027568716 crossrefType "journal-article" @default.
- W2027568716 hasAuthorship W2027568716A5007363668 @default.
- W2027568716 hasAuthorship W2027568716A5036772541 @default.
- W2027568716 hasAuthorship W2027568716A5080274904 @default.
- W2027568716 hasConcept C104317684 @default.
- W2027568716 hasConcept C105580179 @default.
- W2027568716 hasConcept C134018914 @default.
- W2027568716 hasConcept C150194340 @default.
- W2027568716 hasConcept C153911025 @default.
- W2027568716 hasConcept C161176658 @default.
- W2027568716 hasConcept C177707886 @default.
- W2027568716 hasConcept C181199279 @default.
- W2027568716 hasConcept C2780040062 @default.
- W2027568716 hasConcept C2780120631 @default.
- W2027568716 hasConcept C29688787 @default.
- W2027568716 hasConcept C529278444 @default.
- W2027568716 hasConcept C55493867 @default.
- W2027568716 hasConcept C6557445 @default.
- W2027568716 hasConcept C81439078 @default.
- W2027568716 hasConcept C86803240 @default.
- W2027568716 hasConcept C95444343 @default.
- W2027568716 hasConceptScore W2027568716C104317684 @default.
- W2027568716 hasConceptScore W2027568716C105580179 @default.
- W2027568716 hasConceptScore W2027568716C134018914 @default.
- W2027568716 hasConceptScore W2027568716C150194340 @default.
- W2027568716 hasConceptScore W2027568716C153911025 @default.
- W2027568716 hasConceptScore W2027568716C161176658 @default.
- W2027568716 hasConceptScore W2027568716C177707886 @default.
- W2027568716 hasConceptScore W2027568716C181199279 @default.
- W2027568716 hasConceptScore W2027568716C2780040062 @default.
- W2027568716 hasConceptScore W2027568716C2780120631 @default.
- W2027568716 hasConceptScore W2027568716C29688787 @default.
- W2027568716 hasConceptScore W2027568716C529278444 @default.
- W2027568716 hasConceptScore W2027568716C55493867 @default.
- W2027568716 hasConceptScore W2027568716C6557445 @default.
- W2027568716 hasConceptScore W2027568716C81439078 @default.
- W2027568716 hasConceptScore W2027568716C86803240 @default.
- W2027568716 hasConceptScore W2027568716C95444343 @default.
- W2027568716 hasIssue "2" @default.
- W2027568716 hasLocation W20275687161 @default.
- W2027568716 hasLocation W20275687162 @default.
- W2027568716 hasOpenAccess W2027568716 @default.