FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027646895> ?p ?o ?g. }

• W2027646895 endingPage "3959" @default.
• W2027646895 startingPage "3951" @default.
• W2027646895 abstract "The progression of the neoplastic disease is characterized by specific alterations of energy metabolism and by symptoms like fatigue, anorexia, nausea, anaemia, immunodepression and poor performance status (PS). The main cause of these symptoms and metabolic abnormalities is the chronic action of proinflammatory cytokines released both by tumour and immune cells. The present study aimed to assess the relationship between markers of inflammation (C-Reactive Protein, Fibrinogen, proinflammatory cytokines) and energy metabolic status (BMI, leptin, oxidative stress) according to clinical parameters in 104 ovarian cancer patients at different stage and, moreover, to evaluate prospectively the changes of these parameters in accordance to tumour response in a subgroup of 70 advanced stage ovarian cancer patients. Advanced stage and poor PS were associated to high-grade inflammation and impaired energy metabolism. Among inflammatory mediators, interleukin (IL)-6 had a central role as predictive factor of leptin, reactive oxygen species and glutathione peroxidase. In turn, leptin considered the key marker of the nutritional status and energy metabolism, was independently determined from stage and IL-6, not only from BMI. Moreover, the evaluation of the changes of these parameters during the course of the neoplastic disease in the subgroup of advanced ovarian cancer patients clearly unveils the central role of IL-6 and leptin as early markers of the metabolic alterations and symptoms associated to disease progression in advanced stage ovarian cancer. Their assessment should be included in monitoring disease outcome, especially when cancer is no longer curable and quality of life becomes the primary endpoint." @default.
• W2027646895 created "2016-06-24" @default.
• W2027646895 creator A5008174094 @default.
• W2027646895 creator A5045022871 @default.
• W2027646895 creator A5051507235 @default.
• W2027646895 creator A5052761235 @default.
• W2027646895 creator A5060437987 @default.
• W2027646895 creator A5078620057 @default.
• W2027646895 creator A5080262303 @default.
• W2027646895 date "2009-09-01" @default.
• W2027646895 modified "2023-10-14" @default.
• W2027646895 title "Interleukin‐6 and leptin as markers of energy metabolicchanges in advanced ovarian cancer patients" @default.
• W2027646895 cites W1698611201 @default.
• W2027646895 cites W1849884743 @default.
• W2027646895 cites W1918817077 @default.
• W2027646895 cites W1953738763 @default.
• W2027646895 cites W1964863934 @default.
• W2027646895 cites W1966920013 @default.
• W2027646895 cites W1966948292 @default.
• W2027646895 cites W1977114413 @default.
• W2027646895 cites W1980447653 @default.
• W2027646895 cites W1986938381 @default.
• W2027646895 cites W1992170534 @default.
• W2027646895 cites W1994249441 @default.
• W2027646895 cites W1996713062 @default.
• W2027646895 cites W2004793594 @default.
• W2027646895 cites W2007007825 @default.
• W2027646895 cites W2009243031 @default.
• W2027646895 cites W2011924809 @default.
• W2027646895 cites W2017867547 @default.
• W2027646895 cites W2022080250 @default.
• W2027646895 cites W2023445168 @default.
• W2027646895 cites W2037338220 @default.
• W2027646895 cites W2039536423 @default.
• W2027646895 cites W2039870307 @default.
• W2027646895 cites W2056999391 @default.
• W2027646895 cites W2058414050 @default.
• W2027646895 cites W2061114783 @default.
• W2027646895 cites W2062333804 @default.
• W2027646895 cites W2063334442 @default.
• W2027646895 cites W2068186755 @default.
• W2027646895 cites W2072347219 @default.
• W2027646895 cites W2073875673 @default.
• W2027646895 cites W2076229947 @default.
• W2027646895 cites W2076308201 @default.
• W2027646895 cites W2076668534 @default.
• W2027646895 cites W2077405453 @default.
• W2027646895 cites W2077765884 @default.
• W2027646895 cites W2087801360 @default.
• W2027646895 cites W2096335059 @default.
• W2027646895 cites W2100834680 @default.
• W2027646895 cites W2103842373 @default.
• W2027646895 cites W2106325638 @default.
• W2027646895 cites W2118385502 @default.
• W2027646895 cites W2124360707 @default.
• W2027646895 cites W2128868545 @default.
• W2027646895 cites W2133545915 @default.
• W2027646895 cites W2136753100 @default.
• W2027646895 cites W2147272927 @default.
• W2027646895 cites W2150258974 @default.
• W2027646895 cites W2154072617 @default.
• W2027646895 cites W2164489423 @default.
• W2027646895 cites W2167650996 @default.
• W2027646895 cites W2171019010 @default.
• W2027646895 cites W2316534927 @default.
• W2027646895 cites W2334337188 @default.
• W2027646895 cites W4207081528 @default.
• W2027646895 cites W4233349015 @default.
• W2027646895 cites W4253033631 @default.
• W2027646895 doi "https://doi.org/10.1111/j.1582-4934.2008.00408.x" @default.
• W2027646895 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4516542" @default.
• W2027646895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18624749" @default.
• W2027646895 hasPublicationYear "2009" @default.
• W2027646895 type Work @default.
• W2027646895 sameAs 2027646895 @default.
• W2027646895 citedByCount "36" @default.
• W2027646895 countsByYear W20276468952012 @default.
• W2027646895 countsByYear W20276468952013 @default.
• W2027646895 countsByYear W20276468952014 @default.
• W2027646895 countsByYear W20276468952015 @default.
• W2027646895 countsByYear W20276468952016 @default.
• W2027646895 countsByYear W20276468952018 @default.
• W2027646895 countsByYear W20276468952019 @default.
• W2027646895 countsByYear W20276468952020 @default.
• W2027646895 countsByYear W20276468952021 @default.
• W2027646895 countsByYear W20276468952023 @default.
• W2027646895 crossrefType "journal-article" @default.
• W2027646895 hasAuthorship W2027646895A5008174094 @default.
• W2027646895 hasAuthorship W2027646895A5045022871 @default.
• W2027646895 hasAuthorship W2027646895A5051507235 @default.
• W2027646895 hasAuthorship W2027646895A5052761235 @default.
• W2027646895 hasAuthorship W2027646895A5060437987 @default.
• W2027646895 hasAuthorship W2027646895A5078620057 @default.
• W2027646895 hasAuthorship W2027646895A5080262303 @default.
• W2027646895 hasBestOaLocation W20276468951 @default.
• W2027646895 hasConcept C121608353 @default.
• W2027646895 hasConcept C126322002 @default.
• W2027646895 hasConcept C134018914 @default.

• next