FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027720986> ?p ?o ?g. }

• W2027720986 endingPage "2785" @default.
• W2027720986 startingPage "2781" @default.
• W2027720986 abstract "Progenitor-derived endothelial cells (PDECs) isolated from human umbilical cord blood generate a great hope in the fields of vascular tissue engineering. Endothelial cells subjected to shear stress convert mechanical stimuli into intracellular signals that affect cellular functions. It is essential to ensure that PDECs are able to sense shear stress as mature endothelial cells from human saphenous veins (HSVECs) do with mitogen-activated protein (MAP) kinase and nuclear factor (NF)-κB signal transduction pathways. HSVECs and PDECs were seeded on glass slides coated with gelatin and exposed to 12 dyn/cm2 in a parallel-plate flow chamber. In both cell types, shear stress activated extracellular signal-related kinase (ERK)1/2 with a rapid time course (maximum 5 min) followed by a reduced phosphorylation, and p38 pathway. c-Jun N-terminal protein kinase (JNK) phosphorylation is observed only in PDECs. With respect to NF-κB translocation to the nucleus, the NF-κB pathway is not activated by flow in HSVECs and PDECs although interleukin-1α (IL-1α) activates this pathway in both cell types. In our experimental conditions, shear stress does not modify the nuclear translocation of NF-κB in HSVECs after IL-1α stimulation. It can be stated that PDECs are shear stress sensitive and capable of signal transduction as mature HSVECs are, despite the unusual transduction response of both cell types." @default.
• W2027720986 created "2016-06-24" @default.
• W2027720986 creator A5012970827 @default.
• W2027720986 creator A5017781399 @default.
• W2027720986 creator A5025292164 @default.
• W2027720986 creator A5060235809 @default.
• W2027720986 creator A5064398040 @default.
• W2027720986 creator A5067472960 @default.
• W2027720986 creator A5083149438 @default.
• W2027720986 date "2008-08-01" @default.
• W2027720986 modified "2023-10-17" @default.
• W2027720986 title "Unusual transduction response of progenitor-derived and mature endothelial cells exposed to laminar pulsatile shear stress" @default.
• W2027720986 cites W1590987349 @default.
• W2027720986 cites W1978614125 @default.
• W2027720986 cites W1979600880 @default.
• W2027720986 cites W1997454000 @default.
• W2027720986 cites W1999083451 @default.
• W2027720986 cites W2002018258 @default.
• W2027720986 cites W2002903502 @default.
• W2027720986 cites W2007417655 @default.
• W2027720986 cites W2010866783 @default.
• W2027720986 cites W2023302566 @default.
• W2027720986 cites W2029968905 @default.
• W2027720986 cites W2063665585 @default.
• W2027720986 cites W2068538397 @default.
• W2027720986 cites W2080798849 @default.
• W2027720986 cites W2100049315 @default.
• W2027720986 cites W2101770878 @default.
• W2027720986 cites W2124149576 @default.
• W2027720986 cites W2139319526 @default.
• W2027720986 cites W2140860119 @default.
• W2027720986 cites W2148038169 @default.
• W2027720986 cites W2153336030 @default.
• W2027720986 cites W2310033666 @default.
• W2027720986 cites W2335925695 @default.
• W2027720986 cites W4231645290 @default.
• W2027720986 doi "https://doi.org/10.1016/j.jbiomech.2008.06.003" @default.
• W2027720986 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18621377" @default.
• W2027720986 hasPublicationYear "2008" @default.
• W2027720986 type Work @default.
• W2027720986 sameAs 2027720986 @default.
• W2027720986 citedByCount "19" @default.
• W2027720986 countsByYear W20277209862012 @default.
• W2027720986 countsByYear W20277209862013 @default.
• W2027720986 countsByYear W20277209862015 @default.
• W2027720986 countsByYear W20277209862016 @default.
• W2027720986 countsByYear W20277209862018 @default.
• W2027720986 countsByYear W20277209862019 @default.
• W2027720986 countsByYear W20277209862022 @default.
• W2027720986 countsByYear W20277209862023 @default.
• W2027720986 crossrefType "journal-article" @default.
• W2027720986 hasAuthorship W2027720986A5012970827 @default.
• W2027720986 hasAuthorship W2027720986A5017781399 @default.
• W2027720986 hasAuthorship W2027720986A5025292164 @default.
• W2027720986 hasAuthorship W2027720986A5060235809 @default.
• W2027720986 hasAuthorship W2027720986A5064398040 @default.
• W2027720986 hasAuthorship W2027720986A5067472960 @default.
• W2027720986 hasAuthorship W2027720986A5083149438 @default.
• W2027720986 hasConcept C11960822 @default.
• W2027720986 hasConcept C123012128 @default.
• W2027720986 hasConcept C159985019 @default.
• W2027720986 hasConcept C184235292 @default.
• W2027720986 hasConcept C192562407 @default.
• W2027720986 hasConcept C201750760 @default.
• W2027720986 hasConcept C202751555 @default.
• W2027720986 hasConcept C21141959 @default.
• W2027720986 hasConcept C28328180 @default.
• W2027720986 hasConcept C51551487 @default.
• W2027720986 hasConcept C55493867 @default.
• W2027720986 hasConcept C57074206 @default.
• W2027720986 hasConcept C62478195 @default.
• W2027720986 hasConcept C86803240 @default.
• W2027720986 hasConcept C95444343 @default.
• W2027720986 hasConcept C97029542 @default.
• W2027720986 hasConceptScore W2027720986C11960822 @default.
• W2027720986 hasConceptScore W2027720986C123012128 @default.
• W2027720986 hasConceptScore W2027720986C159985019 @default.
• W2027720986 hasConceptScore W2027720986C184235292 @default.
• W2027720986 hasConceptScore W2027720986C192562407 @default.
• W2027720986 hasConceptScore W2027720986C201750760 @default.
• W2027720986 hasConceptScore W2027720986C202751555 @default.
• W2027720986 hasConceptScore W2027720986C21141959 @default.
• W2027720986 hasConceptScore W2027720986C28328180 @default.
• W2027720986 hasConceptScore W2027720986C51551487 @default.
• W2027720986 hasConceptScore W2027720986C55493867 @default.
• W2027720986 hasConceptScore W2027720986C57074206 @default.
• W2027720986 hasConceptScore W2027720986C62478195 @default.
• W2027720986 hasConceptScore W2027720986C86803240 @default.
• W2027720986 hasConceptScore W2027720986C95444343 @default.
• W2027720986 hasConceptScore W2027720986C97029542 @default.
• W2027720986 hasIssue "12" @default.
• W2027720986 hasLocation W20277209861 @default.
• W2027720986 hasLocation W20277209862 @default.
• W2027720986 hasOpenAccess W2027720986 @default.
• W2027720986 hasPrimaryLocation W20277209861 @default.
• W2027720986 hasRelatedWork W1976071046 @default.
• W2027720986 hasRelatedWork W1994953171 @default.
• W2027720986 hasRelatedWork W2056415482 @default.

• next