FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027768727> ?p ?o ?g. }

• W2027768727 endingPage "48" @default.
• W2027768727 startingPage "39" @default.
• W2027768727 abstract "The ATRX protein, associated with X-linked α-thalassaemia, mental retardation and developmental abnormalities including genital dysgenesis, has been proposed to function as a global transcriptional regulator within a multi-protein complex. However, an understanding of the composition and mechanics of this machinery has remained elusive. We applied inter-specific comparative analysis to identify conserved elements which may be involved in regulating the conformation of chromatin. As part of this study, we cloned and sequenced the entire translatable coding region (7.4 kb) of the ATRX gene from a model marsupial (tammar wallaby, Macropus eugenii). We identify an ATRX ancestral core, conserved between plants, fish and mammals, comprising the cysteine-rich and SWI2/SNF2 helicase-like regions and protein interaction domains. Our data are consistent with the model of the cysteine-rich region as a DNA-binding zinc finger adjacent to a protein-binding (plant homeodomain-like) domain. Alignment of vertebrate ATRX sequences highlights other conserved elements, including a negatively charged mammalian sequence which we propose to be involved in binding of positively charged histone tails." @default.
• W2027768727 created "2016-06-24" @default.
• W2027768727 creator A5021054750 @default.
• W2027768727 creator A5034070636 @default.
• W2027768727 creator A5049435272 @default.
• W2027768727 creator A5055073233 @default.
• W2027768727 creator A5058409750 @default.
• W2027768727 creator A5059662490 @default.
• W2027768727 date "2004-09-01" @default.
• W2027768727 modified "2023-09-26" @default.
• W2027768727 title "Comparative analysis of ATRX, a chromatin remodeling protein" @default.
• W2027768727 cites W1277787372 @default.
• W2027768727 cites W1487669901 @default.
• W2027768727 cites W1539442474 @default.
• W2027768727 cites W1599526859 @default.
• W2027768727 cites W1838266191 @default.
• W2027768727 cites W1992641700 @default.
• W2027768727 cites W2003627659 @default.
• W2027768727 cites W2004575181 @default.
• W2027768727 cites W2013313570 @default.
• W2027768727 cites W2019904951 @default.
• W2027768727 cites W2029432280 @default.
• W2027768727 cites W2036584876 @default.
• W2027768727 cites W2043679962 @default.
• W2027768727 cites W2045395748 @default.
• W2027768727 cites W2063365464 @default.
• W2027768727 cites W2077568869 @default.
• W2027768727 cites W2080064173 @default.
• W2027768727 cites W2081404575 @default.
• W2027768727 cites W2084169030 @default.
• W2027768727 cites W2087523122 @default.
• W2027768727 cites W2087687290 @default.
• W2027768727 cites W2094131619 @default.
• W2027768727 cites W2094168284 @default.
• W2027768727 cites W2096791952 @default.
• W2027768727 cites W2098419288 @default.
• W2027768727 cites W2100894245 @default.
• W2027768727 cites W2101813176 @default.
• W2027768727 cites W2113995752 @default.
• W2027768727 cites W2116862022 @default.
• W2027768727 cites W2125600565 @default.
• W2027768727 cites W2128995137 @default.
• W2027768727 cites W2135814705 @default.
• W2027768727 cites W2151598146 @default.
• W2027768727 cites W2188049663 @default.
• W2027768727 cites W2333900189 @default.
• W2027768727 doi "https://doi.org/10.1016/j.gene.2004.06.025" @default.
• W2027768727 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15363844" @default.
• W2027768727 hasPublicationYear "2004" @default.
• W2027768727 type Work @default.
• W2027768727 sameAs 2027768727 @default.
• W2027768727 citedByCount "16" @default.
• W2027768727 countsByYear W20277687272014 @default.
• W2027768727 countsByYear W20277687272016 @default.
• W2027768727 countsByYear W20277687272019 @default.
• W2027768727 countsByYear W20277687272023 @default.
• W2027768727 crossrefType "journal-article" @default.
• W2027768727 hasAuthorship W2027768727A5021054750 @default.
• W2027768727 hasAuthorship W2027768727A5034070636 @default.
• W2027768727 hasAuthorship W2027768727A5049435272 @default.
• W2027768727 hasAuthorship W2027768727A5055073233 @default.
• W2027768727 hasAuthorship W2027768727A5058409750 @default.
• W2027768727 hasAuthorship W2027768727A5059662490 @default.
• W2027768727 hasConcept C104317684 @default.
• W2027768727 hasConcept C161223559 @default.
• W2027768727 hasConcept C167227067 @default.
• W2027768727 hasConcept C167625842 @default.
• W2027768727 hasConcept C179138559 @default.
• W2027768727 hasConcept C199216141 @default.
• W2027768727 hasConcept C24284526 @default.
• W2027768727 hasConcept C2776689207 @default.
• W2027768727 hasConcept C501734568 @default.
• W2027768727 hasConcept C54355233 @default.
• W2027768727 hasConcept C67705224 @default.
• W2027768727 hasConcept C70721500 @default.
• W2027768727 hasConcept C83640560 @default.
• W2027768727 hasConcept C86339819 @default.
• W2027768727 hasConcept C86803240 @default.
• W2027768727 hasConcept C92477616 @default.
• W2027768727 hasConceptScore W2027768727C104317684 @default.
• W2027768727 hasConceptScore W2027768727C161223559 @default.
• W2027768727 hasConceptScore W2027768727C167227067 @default.
• W2027768727 hasConceptScore W2027768727C167625842 @default.
• W2027768727 hasConceptScore W2027768727C179138559 @default.
• W2027768727 hasConceptScore W2027768727C199216141 @default.
• W2027768727 hasConceptScore W2027768727C24284526 @default.
• W2027768727 hasConceptScore W2027768727C2776689207 @default.
• W2027768727 hasConceptScore W2027768727C501734568 @default.
• W2027768727 hasConceptScore W2027768727C54355233 @default.
• W2027768727 hasConceptScore W2027768727C67705224 @default.
• W2027768727 hasConceptScore W2027768727C70721500 @default.
• W2027768727 hasConceptScore W2027768727C83640560 @default.
• W2027768727 hasConceptScore W2027768727C86339819 @default.
• W2027768727 hasConceptScore W2027768727C86803240 @default.
• W2027768727 hasConceptScore W2027768727C92477616 @default.
• W2027768727 hasLocation W20277687271 @default.
• W2027768727 hasLocation W20277687272 @default.
• W2027768727 hasOpenAccess W2027768727 @default.

• next