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- W2027772712 abstract "Cannulated, male albino rats were placed on a 23-hr water deprivation schedule. The animals were allowed a daily 10-min access to an orange extract solution in a large animal cage for 5 days. On the sixth day of deprivation the animals were randomly divided into three groups given either 12% KCI, 25% KCI, or Ringers solution applied unilaterally to the cortex immediately after access to saccharine. On the seventh day of deprivation, each animal was placed in a two-choice situation with an 0.15% saccharine solution and an 0.08% orange extract solution. Both the 12 and 25% KCI groups developed an aversion to the saccharin. EEG recordings verified the presence of cortical spreading depression in both groups. These results verify the finding that cortical spreading depression has aversive properties." @default.
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- W2027772712 date "1977-01-01" @default.
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- W2027772712 title "Cortical spreading depression-induced aversion to saccharin at two levels of KCI: Electroencephalographic verification" @default.
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- W2027772712 doi "https://doi.org/10.1016/s0091-6773(77)91345-1" @default.
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