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- W2027816904 abstract "To evaluate the possibility of metallothionein transfer from liver to kidney, an experimental hepatic disorder produced by carbon tetrachloride was examined to study the release of metallothionein from liver. 109Cd-exposed rats were treated with carbon tetrachloride and the kinetics of cadmium in the body was studied. Hepatic cadmium was significantly decreased in a dose-dependent manner. In contrast, cadmium in plasma, kidney, and urine was increased in proportion to the decrease in hepatic cadmium. No conspicuous changes in cadmium of other tissues and feces were observed. Cadmium in hepatic supernatant of carbon tetrachloride-treated rat was bound mostly to the metallothionein fraction in Sephadex G-75 gel filtration, and in kidney, plasma, or urine, Cd was also in the form of metallothionein. These results suggest that hepatic metallothionein can be released into blood and be transported to kidney and urine in some types of hepatic disorders." @default.
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- W2027816904 date "1995-07-01" @default.
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- W2027816904 title "F1-9 Hepatocyte growth factor-like/macrophage stimulating protein" @default.
- W2027816904 doi "https://doi.org/10.1016/0928-4346(95)90189-e" @default.
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