FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027820338> ?p ?o ?g. }

• W2027820338 abstract "Maternal adrenal steroid hormones have been proven to be crucial for lung and adrenal prenatal maturation. These hormones mediate the effects of prenatal stress crossing the placenta and influencing the development of the hypothalamus-pituitary-adrenal axis of fetuses. In the present study, we have compared the prenatal development of fetuses from adrenalectomized mothers (ADX group) and from sham-operated mothers. We have used immunohistochemistry for calcium binding-protein Calbindin-D28k, astroglial proteins vimentin and glial fibrillary acidic protein (GFAP), and the ultrastructural differentiation of the cerebral cortex and hippocampus to measure putative differences. The ontogeny of the Calbindin-D28k immunoreactivity was delayed, as transient Calbindin-positive neuronal populations in the ADX group disappeared later during development as compared to that of control animals both in cerebral cortex and hippocampus; cell counts revealed that ADX animals had a significantly higher number of Calbindin-positive cells than controls in the cerebral cortex, while that number was lower in ADX fetuses' hippocampus. Cerebral cortex of ADX animals also had a scattered distribution of stained cells compared with controls, while the hippocampi of the ADX animals had an impaired migration of marginal zone interneurons. No GFAP immunoreactivity was found in the studied prenatal stages. Instead, vimentin-immunoreactivity appeared more profusely distributed throughout the cerebral cortex, in the ADX group than in control animals. At the ultrastructural level, no remarkable differences were found before E20, when a higher undifferentiation in the ADX group, in both cerebral cortex and hippocampus, was evident. The results show for the first time the vulnerability of the prenatal rat brain to maternal adrenalectomy and the necessity of maternal glucocorticoids for encephalic development." @default.
• W2027820338 created "2016-06-24" @default.
• W2027820338 creator A5003503810 @default.
• W2027820338 creator A5026251253 @default.
• W2027820338 creator A5048166089 @default.
• W2027820338 creator A5089769928 @default.
• W2027820338 date "1998-06-01" @default.
• W2027820338 modified "2023-10-01" @default.
• W2027820338 title "Calbindin-D28k- and astroglial protein-immunoreactivities, and ultrastructural differentiation in the prenatal rat cerebral cortex and hippocampus are affected by maternal adrenalectomy" @default.
• W2027820338 cites W1916395565 @default.
• W2027820338 cites W1938662700 @default.
• W2027820338 cites W1970602849 @default.
• W2027820338 cites W1978880296 @default.
• W2027820338 cites W1992269159 @default.
• W2027820338 cites W2002110030 @default.
• W2027820338 cites W2005385613 @default.
• W2027820338 cites W2007753092 @default.
• W2027820338 cites W2009858843 @default.
• W2027820338 cites W2012405753 @default.
• W2027820338 cites W2024074982 @default.
• W2027820338 cites W2024822598 @default.
• W2027820338 cites W2024831088 @default.
• W2027820338 cites W2028365448 @default.
• W2027820338 cites W2028637908 @default.
• W2027820338 cites W2030667276 @default.
• W2027820338 cites W2034038906 @default.
• W2027820338 cites W2040074509 @default.
• W2027820338 cites W2041848577 @default.
• W2027820338 cites W2050396530 @default.
• W2027820338 cites W2053965650 @default.
• W2027820338 cites W2055161357 @default.
• W2027820338 cites W2060778950 @default.
• W2027820338 cites W2067166128 @default.
• W2027820338 cites W2068629598 @default.
• W2027820338 cites W2078148562 @default.
• W2027820338 cites W2079579595 @default.
• W2027820338 cites W2086200816 @default.
• W2027820338 cites W2087143337 @default.
• W2027820338 cites W2087690085 @default.
• W2027820338 cites W2090145590 @default.
• W2027820338 cites W2091543295 @default.
• W2027820338 cites W2098950208 @default.
• W2027820338 cites W2105302286 @default.
• W2027820338 cites W2113962949 @default.
• W2027820338 cites W2115534715 @default.
• W2027820338 cites W2118735845 @default.
• W2027820338 cites W2124751829 @default.
• W2027820338 cites W2127247367 @default.
• W2027820338 cites W2138689423 @default.
• W2027820338 cites W2141689891 @default.
• W2027820338 cites W2156625231 @default.
• W2027820338 cites W219068902 @default.
• W2027820338 cites W2197735289 @default.
• W2027820338 cites W2399385461 @default.
• W2027820338 cites W2417540159 @default.
• W2027820338 cites W587429664 @default.
• W2027820338 cites W625423300 @default.
• W2027820338 cites W67419533 @default.
• W2027820338 doi "https://doi.org/10.1016/s0165-3806(98)00047-9" @default.
• W2027820338 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9693794" @default.
• W2027820338 hasPublicationYear "1998" @default.
• W2027820338 type Work @default.
• W2027820338 sameAs 2027820338 @default.
• W2027820338 citedByCount "8" @default.
• W2027820338 crossrefType "journal-article" @default.
• W2027820338 hasAuthorship W2027820338A5003503810 @default.
• W2027820338 hasAuthorship W2027820338A5026251253 @default.
• W2027820338 hasAuthorship W2027820338A5048166089 @default.
• W2027820338 hasAuthorship W2027820338A5089769928 @default.
• W2027820338 hasConcept C112672928 @default.
• W2027820338 hasConcept C126322002 @default.
• W2027820338 hasConcept C134018914 @default.
• W2027820338 hasConcept C169760540 @default.
• W2027820338 hasConcept C203014093 @default.
• W2027820338 hasConcept C204232928 @default.
• W2027820338 hasConcept C26265296 @default.
• W2027820338 hasConcept C2776443723 @default.
• W2027820338 hasConcept C2777348757 @default.
• W2027820338 hasConcept C2777977426 @default.
• W2027820338 hasConcept C2779234561 @default.
• W2027820338 hasConcept C2780495277 @default.
• W2027820338 hasConcept C2781041448 @default.
• W2027820338 hasConcept C2781161787 @default.
• W2027820338 hasConcept C54355233 @default.
• W2027820338 hasConcept C71924100 @default.
• W2027820338 hasConcept C86803240 @default.
• W2027820338 hasConceptScore W2027820338C112672928 @default.
• W2027820338 hasConceptScore W2027820338C126322002 @default.
• W2027820338 hasConceptScore W2027820338C134018914 @default.
• W2027820338 hasConceptScore W2027820338C169760540 @default.
• W2027820338 hasConceptScore W2027820338C203014093 @default.
• W2027820338 hasConceptScore W2027820338C204232928 @default.
• W2027820338 hasConceptScore W2027820338C26265296 @default.
• W2027820338 hasConceptScore W2027820338C2776443723 @default.
• W2027820338 hasConceptScore W2027820338C2777348757 @default.
• W2027820338 hasConceptScore W2027820338C2777977426 @default.
• W2027820338 hasConceptScore W2027820338C2779234561 @default.
• W2027820338 hasConceptScore W2027820338C2780495277 @default.
• W2027820338 hasConceptScore W2027820338C2781041448 @default.
• W2027820338 hasConceptScore W2027820338C2781161787 @default.

• next