FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027831475> ?p ?o ?g. }

• W2027831475 endingPage "203" @default.
• W2027831475 startingPage "197" @default.
• W2027831475 abstract "Toosendanin, a triterpenoid derivative extracted from Melia toosendan Sieb et Zucc, was demonstrated to be a selective presynaptic blocker and an effective antibotulismic agent in previous studies. Here, we observed its effects on Ca(2+) channels in NG108-15 cells by whole-cell patch-clamp recording. Obtained data showed that toosendanin concentration dependently increased the high-voltage-activated (HVA) Ca(2+) current with an EC(50) of 5.13 microM in differentiated NG108-15 cells. The enhancement effect was still observed when the cells were pretreated with 5 microM omega-conotoxin MVIIC. However, when the cells were preincubated with 5 microM nifedipine or 10 microM verapamil-containing solution, the effect was absent. In undifferentiated NG108-15 cells, which only express T-type Ca(2+) channels, toosendanin did not affect Ca(2+) currents. These results show that toosendanin increases Ca(2+) influx in NG108-15 cells via L-type Ca(2+) channels." @default.
• W2027831475 created "2016-06-24" @default.
• W2027831475 creator A5045531454 @default.
• W2027831475 creator A5047445405 @default.
• W2027831475 creator A5056390501 @default.
• W2027831475 creator A5066374436 @default.
• W2027831475 date "2004-06-01" @default.
• W2027831475 modified "2023-10-10" @default.
• W2027831475 title "Toosendanin, a triterpenoid derivative, increases Ca2+ current in NG108-15 cells via L-type channels" @default.
• W2027831475 cites W1460677256 @default.
• W2027831475 cites W1484733768 @default.
• W2027831475 cites W1964550451 @default.
• W2027831475 cites W1970924509 @default.
• W2027831475 cites W1979471962 @default.
• W2027831475 cites W1985536800 @default.
• W2027831475 cites W1986345042 @default.
• W2027831475 cites W1989177581 @default.
• W2027831475 cites W1989663835 @default.
• W2027831475 cites W1993013428 @default.
• W2027831475 cites W1998392188 @default.
• W2027831475 cites W2000781318 @default.
• W2027831475 cites W2002898823 @default.
• W2027831475 cites W2009667219 @default.
• W2027831475 cites W2022968719 @default.
• W2027831475 cites W2039989749 @default.
• W2027831475 cites W2044817944 @default.
• W2027831475 cites W2045375596 @default.
• W2027831475 cites W2051060820 @default.
• W2027831475 cites W2051428235 @default.
• W2027831475 cites W2057630072 @default.
• W2027831475 cites W2074670773 @default.
• W2027831475 cites W2117041071 @default.
• W2027831475 cites W2129074604 @default.
• W2027831475 cites W2141394339 @default.
• W2027831475 cites W2144518570 @default.
• W2027831475 cites W2148261232 @default.
• W2027831475 doi "https://doi.org/10.1016/j.neures.2004.02.012" @default.
• W2027831475 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15140562" @default.
• W2027831475 hasPublicationYear "2004" @default.
• W2027831475 type Work @default.
• W2027831475 sameAs 2027831475 @default.
• W2027831475 citedByCount "19" @default.
• W2027831475 countsByYear W20278314752012 @default.
• W2027831475 countsByYear W20278314752013 @default.
• W2027831475 countsByYear W20278314752017 @default.
• W2027831475 countsByYear W20278314752021 @default.
• W2027831475 countsByYear W20278314752023 @default.
• W2027831475 crossrefType "journal-article" @default.
• W2027831475 hasAuthorship W2027831475A5045531454 @default.
• W2027831475 hasAuthorship W2027831475A5047445405 @default.
• W2027831475 hasAuthorship W2027831475A5056390501 @default.
• W2027831475 hasAuthorship W2027831475A5066374436 @default.
• W2027831475 hasConcept C12554922 @default.
• W2027831475 hasConcept C147944092 @default.
• W2027831475 hasConcept C153461711 @default.
• W2027831475 hasConcept C170493617 @default.
• W2027831475 hasConcept C178790620 @default.
• W2027831475 hasConcept C185592680 @default.
• W2027831475 hasConcept C18699975 @default.
• W2027831475 hasConcept C2777022698 @default.
• W2027831475 hasConcept C2779066535 @default.
• W2027831475 hasConcept C519063684 @default.
• W2027831475 hasConcept C54355233 @default.
• W2027831475 hasConcept C55493867 @default.
• W2027831475 hasConcept C71240020 @default.
• W2027831475 hasConcept C81885089 @default.
• W2027831475 hasConcept C86803240 @default.
• W2027831475 hasConceptScore W2027831475C12554922 @default.
• W2027831475 hasConceptScore W2027831475C147944092 @default.
• W2027831475 hasConceptScore W2027831475C153461711 @default.
• W2027831475 hasConceptScore W2027831475C170493617 @default.
• W2027831475 hasConceptScore W2027831475C178790620 @default.
• W2027831475 hasConceptScore W2027831475C185592680 @default.
• W2027831475 hasConceptScore W2027831475C18699975 @default.
• W2027831475 hasConceptScore W2027831475C2777022698 @default.
• W2027831475 hasConceptScore W2027831475C2779066535 @default.
• W2027831475 hasConceptScore W2027831475C519063684 @default.
• W2027831475 hasConceptScore W2027831475C54355233 @default.
• W2027831475 hasConceptScore W2027831475C55493867 @default.
• W2027831475 hasConceptScore W2027831475C71240020 @default.
• W2027831475 hasConceptScore W2027831475C81885089 @default.
• W2027831475 hasConceptScore W2027831475C86803240 @default.
• W2027831475 hasIssue "2" @default.
• W2027831475 hasLocation W20278314751 @default.
• W2027831475 hasLocation W20278314752 @default.
• W2027831475 hasOpenAccess W2027831475 @default.
• W2027831475 hasPrimaryLocation W20278314751 @default.
• W2027831475 hasRelatedWork W157518455 @default.
• W2027831475 hasRelatedWork W159914829 @default.
• W2027831475 hasRelatedWork W1971168659 @default.
• W2027831475 hasRelatedWork W2029852425 @default.
• W2027831475 hasRelatedWork W2042184998 @default.
• W2027831475 hasRelatedWork W2063814121 @default.
• W2027831475 hasRelatedWork W2350043453 @default.
• W2027831475 hasRelatedWork W2404993779 @default.
• W2027831475 hasRelatedWork W2419295844 @default.
• W2027831475 hasRelatedWork W2432533735 @default.
• W2027831475 hasVolume "49" @default.

• next