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- W2027831705 abstract "Copper sulfate in peroral administration to small experimental animals has an inhibitory effect on the growth of transplanted solid tumors and possesses antidote properties in respect to cisplatin. An antitumor effect of the compound was registered at doses ranging from 10 to 120 mg/kg. Antidote properties are manifested clearly when copper sulfate is applied at a single dose 10 mg/kg, 24 hours before cisplatin administration. It has been determined that copper sulfate decreases acute toxicity, nephro- and hemotoxicity of cisplatin, but fails to change its antitumor effect. The experimental data obtained give the ground for the clinical studies of copper sulfate." @default.
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- W2027831705 date "1988-04-01" @default.
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- W2027831705 title "Effect of the N-terminal fragment of substance P on the microcirculatory system" @default.
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- W2027831705 doi "https://doi.org/10.1007/bf00841178" @default.
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