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- W2027886045 abstract "Caveolae are abundant in skeletal muscle and their coat contains a specific isoform of caveolin, caveolin-3. It has been suggested that during muscle development, caveolin-3 is associated with the T-tubules, but that in adult muscle it is found on the plasma membrane only. We have studied the distribution of caveolin-3 in single skeletal muscle fibers from adult rat soleus by confocal immunofluorescence and by immunogold electron microscopy. We found that caveolin-3 occurs at the highest density on the plasma membrane but is also present in the core of the fibers, at the I-band/A-band interface where it is associated with the T-tubules. In neither domain of the muscle surface does caveolin-3 colocalize with the glucose transporter GLUT4 and there is no evidence for internalization of the caveolae in muscle." @default.
- W2027886045 created "2016-06-24" @default.
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- W2027886045 date "1999-02-01" @default.
- W2027886045 modified "2023-09-23" @default.
- W2027886045 title "Caveolin-3 Is Associated with the T-Tubules of Mature Skeletal Muscle Fibers" @default.
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- W2027886045 doi "https://doi.org/10.1006/excr.1998.4305" @default.
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