Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027911566> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2027911566 endingPage "323" @default.
- W2027911566 startingPage "317" @default.
- W2027911566 abstract "Cartilaginous extracellular matrix (ECM) is a unique assembly of macromolecules such as type II collagen and proteoglycans. In association with a number of accessory molecules, it confers special biological functions on cartilage. Among these various accessory molecules, growth-modulating functions have been identified only in several instances, and in many cases functional properties therefore remain to be elucidated. Chondromodulin-I (ChM-I) is a 25-kDa glycoprotein, which was initially identified in our laboratory as a cartilage-specific functional matrix component that stimulates the growth and matrix synthesis of primary chondrocytes in vitro. We subsequently purified an endothelial cell growth inhibitor from guanidinium extracts of fetal bovine cartilage, which was surprisingly found to be identical to ChM-I. Purified ChM-I was found to inhibit the proliferation of vascular endothelial cells as well as tube morphogenesis in vitro. The generation of a ChM-I null mouse has enabled us to examine the functional roles of this unique ECM component in vivo. In this review, we describe the identification and biological characterization of ChM-I as an example of a growth-modulating functional matrix in cartilage." @default.
- W2027911566 created "2016-06-24" @default.
- W2027911566 creator A5032375068 @default.
- W2027911566 creator A5064941668 @default.
- W2027911566 creator A5069485572 @default.
- W2027911566 creator A5089926644 @default.
- W2027911566 date "2009-01-01" @default.
- W2027911566 modified "2023-10-17" @default.
- W2027911566 title "Chondromodulin-I: A Growth-Modulating Functional Matrix in Cartilage" @default.
- W2027911566 cites W126383820 @default.
- W2027911566 cites W1777581015 @default.
- W2027911566 cites W1971898761 @default.
- W2027911566 cites W1975868048 @default.
- W2027911566 cites W1983579606 @default.
- W2027911566 cites W1989687490 @default.
- W2027911566 cites W1992006238 @default.
- W2027911566 cites W1996330016 @default.
- W2027911566 cites W2009811838 @default.
- W2027911566 cites W2015194336 @default.
- W2027911566 cites W2017793854 @default.
- W2027911566 cites W2029022250 @default.
- W2027911566 cites W2042990447 @default.
- W2027911566 cites W2065133979 @default.
- W2027911566 cites W2091838563 @default.
- W2027911566 cites W2094998020 @default.
- W2027911566 cites W2098326006 @default.
- W2027911566 cites W2133535546 @default.
- W2027911566 cites W2152228240 @default.
- W2027911566 cites W2163145324 @default.
- W2027911566 cites W2167225984 @default.
- W2027911566 doi "https://doi.org/10.2492/inflammregen.29.317" @default.
- W2027911566 hasPublicationYear "2009" @default.
- W2027911566 type Work @default.
- W2027911566 sameAs 2027911566 @default.
- W2027911566 citedByCount "1" @default.
- W2027911566 countsByYear W20279115662015 @default.
- W2027911566 crossrefType "journal-article" @default.
- W2027911566 hasAuthorship W2027911566A5032375068 @default.
- W2027911566 hasAuthorship W2027911566A5064941668 @default.
- W2027911566 hasAuthorship W2027911566A5069485572 @default.
- W2027911566 hasAuthorship W2027911566A5089926644 @default.
- W2027911566 hasBestOaLocation W20279115661 @default.
- W2027911566 hasConcept C104317684 @default.
- W2027911566 hasConcept C105702510 @default.
- W2027911566 hasConcept C106487976 @default.
- W2027911566 hasConcept C108625454 @default.
- W2027911566 hasConcept C185592680 @default.
- W2027911566 hasConcept C189165786 @default.
- W2027911566 hasConcept C202751555 @default.
- W2027911566 hasConcept C2780550940 @default.
- W2027911566 hasConcept C40692019 @default.
- W2027911566 hasConcept C43617362 @default.
- W2027911566 hasConcept C55493867 @default.
- W2027911566 hasConcept C86803240 @default.
- W2027911566 hasConcept C95444343 @default.
- W2027911566 hasConceptScore W2027911566C104317684 @default.
- W2027911566 hasConceptScore W2027911566C105702510 @default.
- W2027911566 hasConceptScore W2027911566C106487976 @default.
- W2027911566 hasConceptScore W2027911566C108625454 @default.
- W2027911566 hasConceptScore W2027911566C185592680 @default.
- W2027911566 hasConceptScore W2027911566C189165786 @default.
- W2027911566 hasConceptScore W2027911566C202751555 @default.
- W2027911566 hasConceptScore W2027911566C2780550940 @default.
- W2027911566 hasConceptScore W2027911566C40692019 @default.
- W2027911566 hasConceptScore W2027911566C43617362 @default.
- W2027911566 hasConceptScore W2027911566C55493867 @default.
- W2027911566 hasConceptScore W2027911566C86803240 @default.
- W2027911566 hasConceptScore W2027911566C95444343 @default.
- W2027911566 hasIssue "5" @default.
- W2027911566 hasLocation W20279115661 @default.
- W2027911566 hasOpenAccess W2027911566 @default.
- W2027911566 hasPrimaryLocation W20279115661 @default.
- W2027911566 hasRelatedWork W1773360809 @default.
- W2027911566 hasRelatedWork W1965221772 @default.
- W2027911566 hasRelatedWork W1972886059 @default.
- W2027911566 hasRelatedWork W1976316234 @default.
- W2027911566 hasRelatedWork W2004390504 @default.
- W2027911566 hasRelatedWork W2009948849 @default.
- W2027911566 hasRelatedWork W2064141435 @default.
- W2027911566 hasRelatedWork W2130255071 @default.
- W2027911566 hasRelatedWork W2330163142 @default.
- W2027911566 hasRelatedWork W98426294 @default.
- W2027911566 hasVolume "29" @default.
- W2027911566 isParatext "false" @default.
- W2027911566 isRetracted "false" @default.
- W2027911566 magId "2027911566" @default.
- W2027911566 workType "article" @default.