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- W2027954399 abstract "A highly specific and sensitive gas chromatographic method has been developed which is capable of determining picogram amounts of dopamine (DA) and norepinephrine (NE) simultaneously. The catecholamines are converted to the N-2,6-dinitro-4-trifluoromethylphenyl, O-trimethylsilyl derivatives, which are analyzed by gas chromatography with electron-capture detection. The method has been applied to the assay of catecholamines in rat brain extracts. One hour after an acute dose (150 mg/kg i.p.) of L-3,4-dihydroxyphenylalanine, the rat brain concentration of DA increased by 130% while the concentration of NE was unchanged." @default.
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- W2027954399 date "1981-06-01" @default.
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- W2027954399 title "Effects of l-dopa on dopamine and norepinephrine concentrations in rat brain assessed by gas chromatography" @default.
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- W2027954399 doi "https://doi.org/10.1016/s0021-9673(00)80342-8" @default.
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