FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2027969837> ?p ?o ?g. }

• W2027969837 endingPage "2211" @default.
• W2027969837 startingPage "2204" @default.
• W2027969837 abstract "During pregnancy, placental CRH acts on human myometrium via specific receptors and might play a role in the regulation of myometrial contractility and hence human parturition. The myometrium is the site of production and target of several PGs, which can be activated by cytokines, especially during infection-induced preterm labor. We established primary human myometrial cell cultures that express functional CRH receptors (CRH-R1alpha, -R1beta, -Rlc, and -R2beta) to investigate the possible regulation of PG production by CRH. We studied the effect of CRH on the two major myometrial PGs, PGE2 and 6-keto PGF1alpha. Human CRH was able to partially inhibit basal, interleukin-1beta-stimulated, and oxytocin-stimulated PGE2 production (56 +/- 11%, 45 +/- 8%, and 58 +/- 6% inhibition, respectively). This effect was blocked by a specific CRH receptor antagonist in a concentration-dependent manner. Furthermore, CRH had no effect on 6-keto PGF1alpha production, indicating that the CRH inhibitory action does not involve suppression of cyclooxygenase, the enzyme responsible for the production of both PGE2 and 6-keto-PGF1alpha. These data further support the view that during pregnancy, CRH may promote myometrial quiescence and might play an important role in the regulation of human labor." @default.
• W2027969837 created "2016-06-24" @default.
• W2027969837 creator A5040672241 @default.
• W2027969837 creator A5071079098 @default.
• W2027969837 date "1999-06-01" @default.
• W2027969837 modified "2023-10-14" @default.
• W2027969837 title "Basal and Interleukin-1β-Stimulated Prostaglandin Production from Cultured Human Myometrial Cells: Differential Regulation by Corticotropin- Releasing Hormone1" @default.
• W2027969837 cites W141984575 @default.
• W2027969837 cites W1797387127 @default.
• W2027969837 cites W1967082963 @default.
• W2027969837 cites W1967133523 @default.
• W2027969837 cites W1968443120 @default.
• W2027969837 cites W1969731732 @default.
• W2027969837 cites W1972101435 @default.
• W2027969837 cites W1979003369 @default.
• W2027969837 cites W1980188841 @default.
• W2027969837 cites W1982193271 @default.
• W2027969837 cites W1982970000 @default.
• W2027969837 cites W1985698173 @default.
• W2027969837 cites W1987894498 @default.
• W2027969837 cites W1988517305 @default.
• W2027969837 cites W1995151968 @default.
• W2027969837 cites W1998784054 @default.
• W2027969837 cites W1999712256 @default.
• W2027969837 cites W2000361669 @default.
• W2027969837 cites W2001006330 @default.
• W2027969837 cites W2004908748 @default.
• W2027969837 cites W2011581449 @default.
• W2027969837 cites W2014420864 @default.
• W2027969837 cites W2021530069 @default.
• W2027969837 cites W2031905952 @default.
• W2027969837 cites W2033893181 @default.
• W2027969837 cites W2035648089 @default.
• W2027969837 cites W2042948119 @default.
• W2027969837 cites W2043016107 @default.
• W2027969837 cites W2044638394 @default.
• W2027969837 cites W2044690408 @default.
• W2027969837 cites W2045155384 @default.
• W2027969837 cites W2046576816 @default.
• W2027969837 cites W2063184509 @default.
• W2027969837 cites W2064666404 @default.
• W2027969837 cites W2077608143 @default.
• W2027969837 cites W2085052924 @default.
• W2027969837 cites W2092198668 @default.
• W2027969837 cites W2108057513 @default.
• W2027969837 cites W2139447909 @default.
• W2027969837 cites W2152737498 @default.
• W2027969837 cites W2169279216 @default.
• W2027969837 cites W2171336797 @default.
• W2027969837 cites W2341699585 @default.
• W2027969837 doi "https://doi.org/10.1210/jcem.84.6.5801" @default.
• W2027969837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10372732" @default.
• W2027969837 hasPublicationYear "1999" @default.
• W2027969837 type Work @default.
• W2027969837 sameAs 2027969837 @default.
• W2027969837 citedByCount "7" @default.
• W2027969837 countsByYear W20279698372013 @default.
• W2027969837 crossrefType "journal-article" @default.
• W2027969837 hasAuthorship W2027969837A5040672241 @default.
• W2027969837 hasAuthorship W2027969837A5071079098 @default.
• W2027969837 hasBestOaLocation W20279698371 @default.
• W2027969837 hasConcept C126322002 @default.
• W2027969837 hasConcept C134018914 @default.
• W2027969837 hasConcept C170493617 @default.
• W2027969837 hasConcept C2776176026 @default.
• W2027969837 hasConcept C2776885963 @default.
• W2027969837 hasConcept C2778024521 @default.
• W2027969837 hasConcept C2778122271 @default.
• W2027969837 hasConcept C2778164554 @default.
• W2027969837 hasConcept C2779066055 @default.
• W2027969837 hasConcept C2779306644 @default.
• W2027969837 hasConcept C2780664492 @default.
• W2027969837 hasConcept C71924100 @default.
• W2027969837 hasConcept C86803240 @default.
• W2027969837 hasConceptScore W2027969837C126322002 @default.
• W2027969837 hasConceptScore W2027969837C134018914 @default.
• W2027969837 hasConceptScore W2027969837C170493617 @default.
• W2027969837 hasConceptScore W2027969837C2776176026 @default.
• W2027969837 hasConceptScore W2027969837C2776885963 @default.
• W2027969837 hasConceptScore W2027969837C2778024521 @default.
• W2027969837 hasConceptScore W2027969837C2778122271 @default.
• W2027969837 hasConceptScore W2027969837C2778164554 @default.
• W2027969837 hasConceptScore W2027969837C2779066055 @default.
• W2027969837 hasConceptScore W2027969837C2779306644 @default.
• W2027969837 hasConceptScore W2027969837C2780664492 @default.
• W2027969837 hasConceptScore W2027969837C71924100 @default.
• W2027969837 hasConceptScore W2027969837C86803240 @default.
• W2027969837 hasIssue "6" @default.
• W2027969837 hasLocation W20279698371 @default.
• W2027969837 hasLocation W20279698372 @default.
• W2027969837 hasOpenAccess W2027969837 @default.
• W2027969837 hasPrimaryLocation W20279698371 @default.
• W2027969837 hasRelatedWork W1979456511 @default.
• W2027969837 hasRelatedWork W1990623083 @default.
• W2027969837 hasRelatedWork W2016071427 @default.
• W2027969837 hasRelatedWork W2027969837 @default.
• W2027969837 hasRelatedWork W2064263717 @default.
• W2027969837 hasRelatedWork W2079690047 @default.

• next